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dc.contributor.authorWyller, Vegard Bruunen_US
dc.contributor.authorFagermoen, Frode Evenen_US
dc.contributor.authorSulheim, Dagen_US
dc.contributor.authorWinger, Anetteen_US
dc.contributor.authorSkovlund, Evaen_US
dc.contributor.authorSaul, J. Philipen_US
dc.date.accessioned2015-03-16T12:37:17Z
dc.date.available2015-03-16T12:37:17Z
dc.date.issued2014-09-15en_US
dc.identifier.citationWyller, V. B., Fagermoen, E., Sulheim, D., Winger, A., Skovlund, E., & Saul, J. P. (2014). Orthostatic responses in adolescent chronic fatigue syndrome: contributions from expectancies as well as gravity. BioPsychoSocial medicine, 8(1), 22.en_US
dc.identifier.issn1751-0759en_US
dc.identifier.issnhttp://dx.doi.org/10.1186/1751-0759-8-22en_US
dc.identifier.otherFRIDAID 1173512en_US
dc.identifier.urihttps://hdl.handle.net/10642/2534
dc.description.abstractBackground Orthostatic intolerance is common in chronic fatigue syndrome (CFS), and several studies have documented an abnormal sympathetic predominance in the autonomic cardiovascular response to gravitational stimuli. The aim of this study was to explore whether the expectancies towards standing are contributors to autonomic responses in addition to the gravitational stimulus itself. Methods A total of 30 CFS patients (12–18 years of age) and 39 healthy controls underwent 20° head-up tilt test and a motor imagery protocol of standing upright. Beat-to-beat cardiovascular variables were recorded. Results At supine rest, CFS patients had significantly higher heart rate, diastolic blood pressure, and mean arterial blood pressure, and lower stroke index and heart rate variability (HRV) indices. The response to 20° head-up tilt was identical in the two groups. The response to imaginary upright position was characterized by a stronger increase of HRV indices of sympathetic predominance (power in the low-frequency range as well as the ratio low-frequency: high-frequency power) among CFS patients. Conclusions These results suggest that in CFS patients expectancies towards orthostatic challenge might be additional determinants of autonomic cardiovascular modulation along with the gravitational stimulus per se.en_US
dc.language.isoengen_US
dc.publisherBioMed Centralen_US
dc.relation.ispartofseriesBioPsychoSocial medicine;8(1)en_US
dc.subjectAdolescenceen_US
dc.subjectAutonomic nervous systemen_US
dc.subjectChronic fatigue syndromeen_US
dc.subjectExpectanciesen_US
dc.subjectOrthostatic intoleranceen_US
dc.titleOrthostatic responses in adolescent chronic fatigue syndrome: Contributions from expectancies as well as gravityen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.version© 2014 Wyller et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_US


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