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dc.contributor.authorMolin, Marianneen_US
dc.contributor.authorBerstad, Paula Mariannaen_US
dc.contributor.authorSaltyte Benth, Jurateen_US
dc.contributor.authorAlexander, Janen_US
dc.contributor.authorPaulsen, Jan Eriken_US
dc.contributor.authorAlmendingen, Karien_US
dc.date.accessioned2014-02-24T09:14:29Z
dc.date.available2014-02-24T09:14:29Z
dc.date.issued2013-02en_US
dc.identifier.citationMolin, M., Berstad, P., BENTH, J. Š., Alexander, J., Paulsen, J. E., & Almendingen, K. (2013). Effect of Different Degrees of Hydrogenated Fish Oil on Intestinal Carcinogenesis in Min/+ mice. Anticancer research, 33(2), 477-483.en_US
dc.identifier.issn0250-7005en_US
dc.identifier.otherFRIDAID 1010800en_US
dc.identifier.urihttps://hdl.handle.net/10642/1859
dc.description.abstractIntake of trans fatty acids from hydrogenated fish oils has been related to increased risk of coronary heart diseases. The possible effect on colorectal carcinogenesis is unclear. Materials and Methods: Multiple intestinal neoplasia (Min/+) mice were fed one of four experimental diets: either raw fish oil (FO), low (LHFO)-, high (HHFO)- or fully-hydrogenated fish oil (FFHO), from 0 to 9 weeks of age. The number and size of intestinal tumors were recorded. Results: There was no difference between the intervention groups in the numbers of developed intestinal tumors. The tumor size was statistically significantly lower in HHFO vs. the FO-group in male Min/+ mice. The HHFO and FHFO groups had lower weight gain than did the FO group (p=0.008 and p=0.04, respectively), but gender differences, due to effect of dietary intervention on weight gain, were found in Min/+ mice. Conclusion: When compared with raw fish oil, different degrees of hydrogenation of the fish oil had no effect on intestinal carcinogenesis in Min/+ mice.en_US
dc.language.isoengen_US
dc.publisherInternational Institute of Anticancer Researchen_US
dc.relation.ispartofseriesAnticancer research;33 (2)en_US
dc.subjectCarcinogenesisen_US
dc.subjectC57BL/6J-Min/+ miceen_US
dc.subjectHydrogenated fish oilen_US
dc.subjectTrans fatty acidsen_US
dc.subjectColorectal canceren_US
dc.titleEffect of Different Degrees of Hydrogenated Fish Oil on Intestinal Carcinogenesis in Min/+ miceen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.identifier.doihttp://ar.iiarjournals.org/content/33/2/477.full.pdf+html


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