Blar i ODA Open Digital Archive på forfatter "Umu, Sinan Uğur"
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HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples
Lagström, Sonja; Løvstad, Alexander H; Umu, Sinan Uğur; Ambur, Ole Herman; Nygård, Mari; Rounge, Trine Ballestad; Christiansen, Irene Kraus (Tumour Virus Research;Volume 12, December 2021, 200221, Peer reviewed; Journal article, 2021-07-14)Human papillomavirus (HPV) 16 and 18 are the most predominant types in cervical cancer. Only a small fraction of HPV infections progress to cancer, indicating that additional factors and genomic events contribute to the ... -
Serum RNA profiling in the 10-year period prior to diagnosis of testicular germ cell tumour
Burton, Joshua; Umu, Sinan Uğur; Langseth, Hilde; Grotmol, Tom; Grimsrud, Tom Kristian; Haugen, Trine B.; Rounge, Trine Ballestad (Frontiers in Oncology;volume 10, Peer reviewed; Journal article, 2020-10-28)Although testicular germ cell tumor (TGCT) overall is highly curable, patients may experience late effects after treatment. An increased understanding of the mechanisms behind the development of TGCT may pave the way for ... -
TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration
Lagström, Sonja; Umu, Sinan Uğur; Lepistö, Maija; Ellonen, Pekka; Meisal, Roger; Christiansen, Irene Kraus; Ambur, Ole Herman; Rounge, Trine Ballestad (Scientific Reports;9, Article number: 524 (2019), Journal article; Peer reviewed, 2018-11-26)HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...