Browsing ODA Open Digital Archive by Author "Pihlstrøm, Lasse"

Now showing items 1-3 of 3

    • Allele-specific expression of Parkinson’s disease susceptibility genes in human brain 

      Langmyhr, Margrete; Henriksen, Sandra Pilar; Cappelletti, Chiara; van de Berg, Wilma D. J.; Pihlstrøm, Lasse; Toft, Mathias (Scientific Reports;11, Article number: 504 (2021), Peer reviewed; Journal article, 2021-01-12)
      Genome-wide association studies have identifed genetic variation in genomic loci associated with susceptibility to Parkinson’s disease (PD), the most common neurodegenerative movement disorder worldwide. We used allelic ...

    • Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease 

      Nordengen, Kaja; Cappelletti, Chiara; Bahrami, Shahram; Frei, Oleksandr; Pihlstrøm, Lasse; Henriksen, Sandra Pilar; Geut, Hanneke; Rozemuller, Annemieke J M; Berg, Wilma D J van de; Andreassen, Ole; Toft, Mathias (Peer reviewed; Journal article, 2023)
      Parkinson’s disease is an age-related neurodegenerative disorder with a higher incidence in males than females. The causes for this sex difference are unknown. Genome-wide association studies (GWAS) have identified 90 ...

    • Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes 

      Cappelletti, Chiara; Henriksen, Sandra Pilar; Geut, Hanneke; Rozemuller, Annemieke J. M.; van de Berg, Wilma D. J.; Pihlstrøm, Lasse; Toft, Mathias (Peer reviewed; Journal article, 2023)
      Parkinson´s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Aggravation of symptoms is mirrored by accumulation of protein aggregates mainly composed by ...