• The association between insomnia, c-reactive protein, and chronic low back pain: Cross-sectional analysis of the HUNT study, Norway 

      Ho, Kevin Kwan Ngai; Simic, Milena; Småstuen, Milada Cvancarova; de Barros Pinheiro, Marina; Ferreira, Paulo Herrique; Johnsen, Marianne Bakke; Heuch, Ingrid; Grotle, Margreth; Zwart, John-Anker; Nilsen, Kristian Bernhard (Scandinavian Journal of Pain;Volume 19: Issue 4, Journal article; Peer reviewed, 2019-07-09)
      Background and aims: Chronic low back pain (chronic LBP) is the number one cause for years lived with disability among 301 diseases and injuries analyzed by The Global Burden of Disease study 2013. Insomnia is highly ...
    • Can within-subject comparisons of thermal thresholds be used for diagnostic purposes? 

      Dunker, Øystein; Lie, Marie; Nilsen, Kristian Bernhard (Clinical Neurophysiology Practice;Volume 6, Peer reviewed; Journal article, 2021-02-04)
      Objective: Quantitative thermal testing (QTT) is a psychophysical assessment method of small nerve fibers that relies on reference material to assess function. Normal limits for within-subject comparisons of thermal ...
    • Clinical and vascular responses topropranolol and candesartan in migraine patients: A randomized controlled clinical trial 

      Barzenje, Aros D; Gjesdal, Knut; Winsvold, Bendik K S; Småstuen, Milada Cvancarova; Stovner, Lars Jacob; Gravdahl, Gøril Bruvik; Nilsen, Kristian Bernhard (Cephalalgia Reports;Volume 3(January-December), Journal article; Peer reviewed, 2020-10-07)
      Background: Both propranolol and candesartan are prophylactic drugs for migraine, but with unknown mechanisms of action. The objectives of the present study were to investigate these drugs’ effects on arterial wall dynamics ...
    • Clinical Utility of the 6-Item CTS, Boston-CTS, and Hand-Diagram for Carpal Tunnel Syndrome 

      Schulze, Daniel Gregor; Nilsen, Kristian Bernhard; Killingmo, Rikke Munk; Zwart, John Anker; Grotle, Margreth (Frontiers in Neurology;July 2021 | Volume 12 | Article 683807, Peer reviewed; Journal article, 2021-07-27)
      Background: Self-reported measures are often used in research and clinical practice to diagnose carpal tunnel syndrome (CTS) and guide therapeutic choices. We aimed to assess the clinical utility of the Norwegian versions ...
    • Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions 

      Khoury, Samar; Parisien, Marc; Thompson, Scott J.; Vachon-Presseau, Etienne; Roy, Mathieu; Mitchell, Amy; Winsvold, Bendik K S; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Fors, Egil Andreas; Heuch, Ingrid; Nielsen, Jonas Bille; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Kania, Artur; Mogil, Jeffrey S.; Diatchenko, Luda (Brain;Volume 145, Issue 3, Peer reviewed; Journal article, 2021-11-11)
      Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is ...
    • Impact of technical variations on the ring-finger test for carpal tunnel syndrome 

      Schulze, Daniel Gregor; Nordby, Karl-Christian; Småstuen, Milada Cvancarova; Clemm, Thomas; Grotle, Margreth; Zwart, John-Anker; Nilsen, Kristian Bernhard (Clinical Neurophysiology Practice;Volume 5, 2020, Journal article; Peer reviewed, 2019-11-23)
    • Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC 

      Lie, Marie; Pedersen, Linda Margareth; Heuch, Ingrid; Winsvold, Bendik K S; Gjerstad, Johannes; Hasvik, Eivind Olay; Nygaard, Øystein Petter; Grotle, Margreth; Matre, Dagfinn; Zwart, John Anker Henrik; Nilsen, Kristian Bernhard (Frontiers in Genetics;January 2022 | Volume 12 | Article 757632, Peer reviewed; Journal article, 2022-01-24)
      In a recently published genome-wide association study (GWAS) chronic back pain was associated with three loci; SOX5, CCDC26/GSDMC and DCC. This GWAS was based on a heterogeneous sample of back pain disorders, and it is ...
    • Psychophysical or spinal reflex measures when assessing conditioned pain modulation? 

      Lie, Marie; Petriu, Elena; Matre, Dagfinn; Hansson, Per; Andersen, Ole Kæseler; Zwart, John-Anker; Nilsen, Kristian Bernhard (European Journal of Pain;Volume 23, Issue 10, November 2019, Journal article; Peer reviewed, 2019-07-29)
      Background: Assessing conditioning pain modulation (CPM) with spinal reflex measures may produce more objective and stable CPM effects than using psychophysical measures. The aim of the study was to compare the CPM effect ...
    • A tonic heat test stimulus yields a larger and more reliable conditioned pain modulation effect compared to a phasic heat test stimulus 

      Lie, Marie; Matre, Dagfinn; Hansson, Per; Stubhaug, Audun; Zwart, John-Anker; Nilsen, Kristian Bernhard (Pain Reports;Volume 2 - Issue 6, Journal article; Peer reviewed, 2017-11)
      Introduction: The interest in conditioned pain modulation (CPM) as a clinical tool for measuring endogenously induced analgesia is increasing. There is, however, large variation in the CPM methodology, hindering comparison ...