Browsing ODA Open Digital Archive by Author "Hjermstad, Marianne Jensen"
Now showing items 1-11 of 11
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Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series
Yule, Michael S.; Thompson, Joshua; Leesahatsawat, Khachonphat; Sousa, Mariana S.; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Dajani, Olav; Fallon, Marie; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; McDonald, James; McGovern, Josh; Roeland, Eric J.; Sayers, Judith; Skipworth, Richard J.E.; Ottestad, Inger; Philips, Iain; Simpson, Melanie Rae; Solheim, Tora S; Vagnildhaug, Ola Magne; McMillan, Donald; Laird, Barry J; Dolan, Ross D. (Peer reviewed; Journal article, 2024)Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement ... -
Comparing two classifications of cancer cachexia and their association with survival in patients with unresected pancreatic cancer
Wesseltoft-Rao, Nima; Hjermstad, Marianne Jensen; Andersen, Tone Ikdahl; Dajani, Olav; Ulven, Stine Marie; Iversen, Per Ole; Bye, Asta (Journal article; Peer reviewed, 2015-02-24)Cancer cachexia is characterized by reduced weight and muscle mass, poor treatment tolerance and short survival. A universally accepted definition of this condition lacks. Two classifications have recently been proposed; ... -
A comparison of CT based measures of skeletal muscle mass and density from the Th4 and L3 levels in patients with advanced non-small-cell lung cancer
Grønberg, Bjørn Henning; Sjøblom, Bjørg; Wentzel-Larsen, Tore; Baracos, Vickie Elaine; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Bremnes, Roy M.; Fløtten, Øystein; Bye, Asta; Jordhøy, Marit Slaaen (European Journal of Clinical Nutrition;, Journal article; Peer reviewed, 2018-09-25)Background: Muscle mass and density assessed from CT-images at the L3 level are prognostic for survival and predict toxicity in cancer patients. However, L3 is not always included on routine CT-scans. We aimed to investigate ... -
Effects of individualized nutrition after allogeneic hematopoietic stem cell transplantation following myeloablative conditioning; a randomized controlled trial
Skaarud, Kristin Aneta Joan; Hjermstad, Marianne Jensen; Bye, Asta; Veierød, Marit Bragelien; Gudmundstuen, Anne Marte; Lundin, Knut Erik Aslaksen; Distante, Sonia; Brinch, Lorentz; Tjønnfjord, Geir Erland; Iversen, Per Ole (Clinical Nutrition ESPEN;Volume 28, December 2018, Journal article; Peer reviewed, 2018-08-29)Background & aims: Reduced quality of life (QoL) is prevalent after allogeneic hematopoietic stem cell transplantation (allo-HSCT). In this randomized trial we examined the effect of individualized nutritional support ... -
En prospektiv kartlegging av risiko for underernæring blant pasienter som får strålebehandling mot endetarms og analkreft
Rahimi, Shahla (Master thesis, 2011)The purpose of this study was to illustrate if the survey of nutritional risk and efforts against malnutrition is feasible during radiotherapy in the departemment of Oncology patients with rectal and anal cancer. Subjects ... -
Muscle mass and association to quality of life in non-small cell lung cancer patients
Bye, Asta; Sjøblom, Bjørg; Wentzel-Larsen, Tore; Grønberg, Bjørn Henning; Baracos, Vickie E.; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Bremnes, Roy M.; Fløtten, Øystein; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2017)Background Cancer wasting is characterized by muscle loss and may contribute to fatigue and poor quality of life (QoL). Our aim was to investigate associations between skeletal muscle index (SMI) and skeletal muscle ... -
Norwegian reference values for the Short-Form Health Survey 36: development over time
Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2017)Purpose Reference values for patient-reported outcome measures are useful for interpretation of results from clinical trials. The study aims were to collect Norwegian SF-36 reference values and compare with data from ... -
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ... -
Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy
Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (International Journal of Obesity;Volume 46, Issue 4, Peer reviewed; Journal article, 2022-01-01)Background/objectives: There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ... -
Symptoms in advanced pancreatic cancer are of importance for energy intake
Bye, Asta; Jordhøy, Marit S.; Skjegstad, Grete; Ledsaak, Oddlaug; Iversen, Per Ole; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2012-06-10)Purpose Cancer cachexia and low energy intake (EI) probably contribute to weight loss in advanced pancreatic cancer (PC). However, little is known about the actual EI in this disease. Aims were to assess EI, weight loss ... -
Use of radiotherapy in breast cancer patients with brain metastases - a retrospective 11-year single center study
Gullhaug, Anna; Hjermstad, Marianne Jensen; Yri, Olav Erich; Svestad, Jørund Graadal; Aass, Nina Kathrine; Johansen, Safora (Journal of Medical Imaging and Radiation Sciences;, Peer reviewed; Journal article, 2021-02-03)Aim: To analyse the use of radiotherapy (RT) and factors affecting overall survival (OS) after RT in breast cancer patients with brain metastases. Methods: Breast cancer patients treated from 2008 to 2018 with whole brain ...