Browsing ODA Open Digital Archive by Author "Aabakken, Lars"
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Relationship between fecal content of fatty acids and cyclooxygenase mRNA expression and fatty acid composition in duodenal biopsies, serum lipoproteins, and dietary fat in colectomized familial adenomatous polyposis patients
Almendingen, Kari; Høstmark, Arne Torbjørn; Larsen, Laila Norheim; Fausa, Olav; Bratlie, Jorunn; Aabakken, Lars (Journal article; Peer reviewed, 2010)A few familial adenomatous polyposis studies have focused upon faecal sterols and bile acids but none has analysed the fecal content of fatty acids. We report here findings of an observational study on 29 colectomized ... -
Resection rates and intention-to-treat outcomes in borderline and locally advanced pancreatic cancer: real-world data from a population-based, prospective cohort study (NORPACT-2)
Farnes, Ingvild; Kleive, Dyre; Verbeke, Caroline Sophie; Aabakken, Lars; Issa-Epe, Aart Imran; Småstuen, Milada Cvancarova; Fosby, Bjarte; Dueland, Svein; Line, Pål Dag; Labori, Knut Jørgen (Peer reviewed; Journal article, 2023)Background: Systemic chemotherapy is the initial treatment strategy for borderline resectable and locally advanced pancreatic cancer to facilitate curative resection. The aim of this study was to investigate the resection ... -
Selective COX-2 inhibition affects fatty acids, but not COX mRNA expression in patients with FAP
Almendingen, Kari; Larsen, Laila Norheim; Fausa, Olav; Bratlie, Jorunn; Høstmark, Arne Torbjørn; Aabakken, Lars (Journal article; Peer reviewed, 2010-07)Familial adenomatous polyposis (FAP) provides a model for sporadic colorectal cancer development. Cyclooxygenase (COX) inhibition may ameliorate polyp development, but rofecoxib was withdrawn due to cardiovascular side ...