Blar i ODA Open Digital Archive på tidsskrift "Scientific Reports"

Viser treff 21-24 av 24

    • TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration 

      Lagström, Sonja; Umu, Sinan Uğur; Lepistö, Maija; Ellonen, Pekka; Meisal, Roger; Christiansen, Irene Kraus; Ambur, Ole Herman; Rounge, Trine Ballestad (Scientific Reports;9, Article number: 524 (2019), Journal article; Peer reviewed, 2018-11-26)
      HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...

    • Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer 

      Kiselev, Yury; Andersen, Sigve; Johannessen, Charles; Fjukstad, Bjørn; Olsen, Karina Standahl; Stenvold, Helge; Al-Saad, Samer; Dønnem, Tom; Richardsen, Elin; Bremnes, Roy M.; Busund, Lill-Tove (Scientific Reports;Volume 8, Article number: 5059 (2018), Journal article; Peer reviewed, 2018-03-22)
      Lung cancer is the leading cause of cancer deaths. Novel predictive biomarkers are needed to improve treatment selection and more accurate prognostication. PAX6 is a transcription factor with a proposed tumour suppressor ...

    • Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease 

      Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen; Yazdani, Mazyar; Lagali, Neil Satish; Vitelli, Valeria; Dartt, Darlene Ann; Chen, Xiangjun (Scientific Reports;10, Article number: 5542 (2020), Journal article; Peer reviewed, 2020-03-26)
      The prevalence of dry eye disease is high worldwide and poses a great burden on patients’ daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is ...

    • Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism 

      Lund, Jenny; Aas, Vigdis; Tingstad, Ragna Husby; Van Hees, Alfons; Nikolic, Natasa (Scientific Reports;8, Article number: 9814 (2018), Journal article; Peer reviewed, 2018-06-29)
      Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular ...