Blar i ODA Open Digital Archive på forfatter "Brox, Jens Ivar"
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Adherence to self-managed exercises for patients with persistent subacromial pain. The Ad-Shoulder feasibility study
Major, Daniel Høgli; Grotle, Margreth; Littlewood, Chris; Brox, Jens Ivar; Matre, Dagfinn; Gallet, Heidi V.; Røe, Yngve (Pilot and Feasibility Studies;7, Article number: 31 (2021), Journal article; Peer reviewed, 2021-01-25)Background: Exercise is recommended for patients with subacromial pain. It has been suggested that good exercise adherence improves clinical outcomes. Despite this, little attention has been paid to the need for behavioural ... -
Adjacent Disc Degeneration After Lumbar Total Disc Replacement or Non-operative Treatment: A Randomized Study With Eight-year Follow-up.
Furunes, Håvard; Hellum, Christian; Espeland, Ansgar; Brox, Jens Ivar; Småstuen, Milada C; Berg, Linda; Storheim, Kjersti (Spine;Volume 43, Number 24, Journal article; Journal article; Peer reviewed, 2018-12-01)Study design: Randomized controlled multicenter trial with eight-year follow-up. Objective; To assess the long-term development of adjacent disc degeneration (ADD) after lumbar total disc replacement (TDR) or non-operative ... -
Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial.
Storheim, Kjersti; Espeland, Ansgar; Grøvle, Lars; Skouen, Jan Sture; Assmus, Jörg; Anke, Audny; Froholdt, Anne; Pedersen, LM; Haugen, AJ; Fors, Terese; Schistad, Ellina Iordanova; Lutro, Olav; Marchand, Gunn Hege; Kadar, Thomas; Vetti, Nils; Randen, Solfrid; Nygaard, Øystein Petter; Brox, Jens Ivar; Grotle, Margreth; Zwart, JA (Journal article; Peer reviewed, 2017)Background A previous randomised controlled trial (RCT) of patients with chronic low back pain (LBP) and vertebral bone marrow (Modic) changes (MCs) on magnetic resonance imaging (MRI), reported that a 3-month, high-dose ... -
Apparent diffusion coefficient values in Modic changes – interobserver reproducibility and relation to Modic type
Dagestad, Magnhild Hammersland; Vetti, Nils; Kristoffersen, Per M; Zwart, John Anker Henrik; Storheim, Kjersti; Bakland, Gunnstein; Brox, Jens Ivar; Grøvle, Lars; Marchand, Gunn Hege; Andersen, Erling; Assmus, Jörg; Espeland, Ansgar (BMC Musculoskeletal Disorders;23, Article number: 695 (2022), Peer reviewed; Journal article, 2022-07-22)Background: Modic Changes (MCs) in the vertebral bone marrow were related to back pain in some studies but have uncertain clinical relevance. Difusion weighted MRI with apparent difusion coefcient (ADC)-measurements can ... -
Association of Modic change types and their short tau inversion recovery signals with clinical characteristics : a cross sectional study of chronic low back pain patients in the AIM-study
Bråten, Lars Christian Haugli; Schistad, Ellina Iordanova; Espeland, Ansgar; Kristoffersen, Per M; Haugen, Anne Julsrud; Marchand, Gunn Hege; Vetti, Nils; Pripp, Are Hugo; Kadar, Thomas; Skouen, Jan Sture; Grotle, Margreth; Grøvle, Lars; Zwart, John-Anker; Brox, Jens Ivar; Storheim, Kjersti (BMC Musculoskeletal Disorders;21, Article number: 368 (2020), Journal article; Peer reviewed, 2020-06-10)Background: Modic Changes (MCs, magnetic resonance imaging (MRI) signal changes in the vertebral bone marrow extending from the vertebral endplate) may represent a subgroup of nonspecific chronic low back pain that could ... -
Associations between shoulder pain and functioning on the ICF Checklist and the Disabilities of the Arm, Shoulder and Hand scale – a cross-sectional study
Søberg, Helene L.; Engebretsen, Kaia Beck; Juel, Niels Gunnar; Røe, Yngve; Brox, Jens Ivar (Disability and Rehabilitation;Published online 23 Mar 2019, Journal article; Peer reviewed, 2019-02-04)Purpose: The association between patients’ shoulder pain and functioning according to the International Classification of Functioning, Disability, and Health (ICF), and outcome on a condition specific patient reported ... -
Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - Secondary analyses of a randomised, placebo-controlled trial (the AIM study)
Bråten, Lars Christian Haugli; Grøvle, Lars; Espeland, Ansgar; Pripp, Are Hugo; Grotle, Margreth; Hellum, Christian; Haugen, Anne Julsrud; Froholdt, Anne; Rolfsen, Mads Peder; Nygaard, Øystein Petter; Lutro, Olav; Kristoffersen, Per Martin; Anke, Audny; Schistad, Ellina Iordanova; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (BMC Musculoskeletal Disorders;21, Article number: 458 (2020), Journal article; Peer reviewed, 2020-07-13)Background: Randomised trials on antibiotic treatment for patients with chronic low back pain and vertebral endplate changes visible on MRI (Modic changes) have shown mixed results. A possible explanation might be a real ... -
Comparable increases in dural sac area after three different posterior decompression techniques for lumbar spinal stenosis: radiological results from a randomized controlled trial in the NORDSTEN study
Hermansen, Erland; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Myklebust, Tor Åge; Aaen, Jørn Ståle; Banitalebi, Hasan; Anvar, Masoud D; Rekeland, Frode; Brox, Jens Ivar; Franssen, Eric; Weber, Clemens; Solberg, Tore; Haug, Knut Jørgen; Grundnes, Oliver; Brisby, Helena; Indrekvam, Kari (European spine journal;, Journal article; Peer reviewed, 2020-06-18)Purpose: To investigate changes in dural sac area after three different posterior decompression techniques in patients undergoing surgery for lumbar spinal stenosis. Summary of background data: Decompression of the ... -
Comparison of the SF6D, the EQ5D, and the oswestry disability index in patients with chronic low back pain and degenerative disc disease
Johnsen, Lars Gunnar; Hellum, Christian; Nygaard, Øystein Petter; Storheim, Kjersti; Brox, Jens Ivar; Rossvoll, Ivar; Leivseth, Gunnar; Grotle, Margreth (BMC musculoskeletal disorders;14(1), Journal article; Peer reviewed, 2013-04-26)Background The need for cost effectiveness analyses in randomized controlled trials that compare treatment options is increasing. The selection of the optimal utility measure is important, and a central question is ... -
Costs of shoulder pain and resource use in primary health care: a cost-of-illness study in Sweden
Virta, Lena; Joranger, Pål; Brox, Jens Ivar; Eriksson, Rikard (BMC Musculoskeletal Disorders;13 (17), Journal article; Peer reviewed, 2012)Background: Painful shoulders pose a substantial socioeconomic burden. A prospective cost-of-illness study was performed to assess the costs associated with healthcare use and loss of productivity in patients with ... -
Cost–utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study)
Grotle, Margreth; Bråten, Lars Christian Haugli; Brox, Jens Ivar; Espeland, Ansgar; Zolic-Karlsson, Zinajda; Killingmo, Rikke Munk; Tingulstad, Alexander; Grøvle, Lars; Johanessen, Anne Froholdt; Kristoffersen, Per Martin; Wigemyr, Monica; van Tulder, Maurits W.; Storheim, Kjersti; Zwart, John-Anker (BMJ Open;Volume 10, Issue 6, Journal article; Peer reviewed, 2020-06-15)Objective: To evaluate the cost–utility of 100 days of antibiotics in patients with chronic low back pain (LBP) and type I or II Modic changes included in the Antibiotic treatment In patients with chronic low back pain and ... -
Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)
Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Gervin, Kristina; Pripp, Are Hugo; Skouen, Jan Sture; Schistad, Elina Iordanova; Pedersen, Linda Margareth; Wigemyr, Monica; Selmer, Kaja Kristine; Dalsbotten Aass, Hans Christian; Goll, Guro Løvik; Brox, Jens Ivar; Espeland, Ansgar; Grøvle, Lars; Zwart, John Anker Henrik; Storheim, Kjersti (Peer reviewed; Journal article, 2023)Objective: Randomized trials testing the effect of antibiotics for chronic low back pain (LBP) with vertebral bone marrow changes on MRI (Modic changes) report inconsistent results. A proposed explanation is subgroups ... -
Decompression alone versusdecompression with instrumental fusionthe NORDSTEN degenerativespondylolisthesis trial (NORDSTEN-DS);study protocol for a randomized controlledtrial
Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Lønne, Greger; Indrekvam, Kari; Aaen, Jørn; Grundnes, Oliver; Hellum, Christian (BMC Musculoskeletal Disorders;20:07, Journal article; Peer reviewed, 2018-12-18)Background Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting ... -
Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis
Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten Wang; Storheim, Kjersti; Brox, Jens Ivar; Solberg, Tore; Rekeland, Frode; Franssen, Eric; Weber, Clemens; Brisby, Helena; Grundnes, Oliver; Algaard, Knut; Bøker, Tordis; Banitalebi, Hasan; Indrekvam, Kari; Hellum, Christian (New England Journal of Medicine;Vol. 385, No. 6, Peer reviewed; Journal article, 2021-08-05)Background: In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion. Methods: We conducted ... -
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
Gjefsen, Elisabeth; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Wigemyr, Monica; Bolstad, Nils; Valberg, Morten; Schistad, Ellina Iordanova; Marchand, Gunn Hege; Granviken, Fredrik; Selmer, Kaja Kristine; Johanessen, Anne Froholdt; Haugen, Anne Julsrud; Dagestad, Magnhild Hammersland; Vetti, Nils; Bakland, Gunnstein; Lie, Benedicte Alexandra; Haavardsholm, Espen A.; Nilsen, Aksel Thuv; Holmgard, Thor Einar; Kadar, Thomas; Kvien, Tore Kristian; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Espeland, Ansgar; Storheim, Kjersti; Zwart, John-Anker (BMC Musculoskeletal Disorders;21, Article number: 698 (2020), Journal article; Peer reviewed, 2020-10-21)Background: Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Espeland, Ansgar; Wigemyr, Monica; Assmus, Jörg; Froholdt, Anne; Haugen, Anne Julsrud; Marchand, Gunn Hege; Kristoffersen, Per M; Lutro, Olav; Randen, Sigrun; Wilhelmsen, Maja; Winsvold, Bendik K S; Kadar, Thomas; Holmgard, Thor Einar; Vigeland, Maria Dehli; Vetti, Nils; Nygaard, Øystein Petter; Lie, Benedicte Alexandra; Hellum, Christian; Anke, Audny; Grotle, Margreth; Schistad, Ellina Iordanova; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (BMJ; 2019;367:l5654, Journal article; Peer reviewed, 2019-08-29)Objective: To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). Design: ... -
Evaluation of the EQ-5D-3L and 5L versions in low back pain patients
Garratt, Andrew; Furunes, Håvard; Hellum, Christian; Solberg, Tore; Brox, Jens Ivar; Storheim, Kjersti; Johnsen, Lars Gunnar (Health and Quality of Life Outcomes;19:155, Peer reviewed; Journal article, 2021-05-28)Background: The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. ... -
Follow-up score, change score or percentage change score for determining clinical important outcome following surgery? An observational study from the Norwegian registry for Spine surgery evaluating patient reported outcome measures in lumbar spinal stenosis and lumbar degenerative spondylolisthesis
Austevoll, Ivar Magne; Gjestad, Rolf; Grotle, Margreth; Solberg, Tore; Brox, Jens Ivar; Hermansen, Erland; Rekeland, Frode; Indrekvam, Kari; Storheim, Kjersti; Hellum, Christian (BMC Musculoskeletal Disorders;20(31), Journal article; Peer reviewed, 2019)Assessment of outcomes for spinal surgeries is challenging, and an ideal measurement that reflects all aspects of importance for the patients does not exist. Oswestry Disability Index (ODI), EuroQol (EQ-5D) and Numeric ... -
A health economic evaluation of screening and treatment in patients with adolescent idiopathic scoliosis
Adobor, Raphael Dziwornu; Joranger, Pål; Steen, Harald; Navrud, Ståle; Brox, Jens Ivar (Scoliosis;9(21), Journal article; Peer reviewed, 2014)Summary of background data Adolescent idiopathic scoliosis can progress and affect the health related quality of life of the patients. Research shows that screening is effective in early detection, which allows for bracing ... -
Lumbar total disc replacement: predictors for long-term outcome
Furunes, Håvard; Hellum, Christian; Brox, Jens Ivar; Rossvoll, Ivar; Espeland, Ansgar; Berg, Linda; Brøgger, Helga Maria; Småstuen, Milada C; Storheim, Kjersti (Journal article; Peer reviewed, 2017)Purpose We aimed to identify patient characteristics associated with favourable long-term outcomes after lumbar total disc replacement (TDR). Methods We analysed a cohort of 82 patients with degenerative disc and ...