Browsing ODA Open Digital Archive by Author "Østeby, Anja"
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Bridging the polar and hydrophobicmMetabolome in single-run untargeted liquid chromatography-mass spectrometry dried blood spot metabolomics for clinical purposes
Skogvold, Hanne Bendiksen; Sandås, Elise Mørk; Østeby, Anja; Løkken, Camilla; Rootwelt, Helge; Rønning, Per Ola; Wilson, Steven Ray Haakon; Elgstøen, Katja Benedikte Prestø (Peer reviewed; Journal article, 2021)Dried blood spot (DBS) metabolite analysis is a central tool for the clinic, e.g., newborn screening. Instead of applying multiple analytical methods, a single liquid chromatography-mass spectrometry (LC–MS) method was ... -
A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics
Skogvold, Hanne Bendiksen; Yazdani, Mazyar; Mørk Sandås, Elise; Østeby, Anja; Kristensen, Erle; Haarr, Dagfinn; Rootwelt, Helge; Elgstøen, Katja B. Prestø (Peer reviewed; Journal article, 2021)The neurotoxin 3-nitropropionic acid (3-NPA) is an inhibitor of succinate dehydrogenase, an enzyme participating both in the citric acid cycle and the mitochondrial respiratory chain. In human intoxications, it produces ...