dc.contributor.author | Garratt, Andrew | |
dc.contributor.author | Furunes, Håvard | |
dc.contributor.author | Hellum, Christian | |
dc.contributor.author | Solberg, Tore | |
dc.contributor.author | Brox, Jens Ivar | |
dc.contributor.author | Storheim, Kjersti | |
dc.contributor.author | Johnsen, Lars Gunnar | |
dc.date.accessioned | 2021-06-24T13:52:02Z | |
dc.date.available | 2021-06-24T13:52:02Z | |
dc.date.created | 2021-06-15T13:39:52Z | |
dc.date.issued | 2021-05-28 | |
dc.identifier.citation | Health and Quality of Life Outcomes. 2021, 19, (1-9). | en_US |
dc.identifier.issn | 1477-7525 | |
dc.identifier.uri | https://hdl.handle.net/11250/2761200 | |
dc.description.abstract | Background: The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. Evidence from healthy and sick populations shows that the additional two response categories improve measurement properties but there has not been a concurrent comparison of the two versions in patients with low back pain (LBP).
Methods: LBP patients taking part in a multicenter randomized controlled trial of lumbar total disc replacement and conservative treatment completed the EQ-5D-3L and 5L in an eight-year follow-up questionnaire. The 3L and 5L were assessed for aspects of data quality including missing data, floor and ceiling effects, response consistency, and based on a priori hypotheses, associations with the Oswestry Disability Index (ODI), Pain-Visual Analogue Scales and Hopkins Symptom Checklist (HSCL-25).
Results: At the eight-year follow-up, 151 (87%) patients were available and 146 completed both the 3L and 5L. Levels of missing data were the same for the two versions. Compared to the EQ-5D-5L, the 3L had significantly higher floor (pain discomfort) and ceiling effects (mobility, self-care, pain/discomfort, anxiety/depression). For these patients the EQ-5D-5L described 73 health states compared to 28 for the 3L. Shannon’s indices showed the 5L outperformed the 3L in tests of classification efficiency. Correlations with the ODI, Pain-VAS and HSCL-25 were largely as hypothesized, the 5L having slightly higher correlations than the 3L.
Conclusion: The EQ-5D assesses important aspect of health in LBP patients and the 5L improves upon the 3L in this respect. The EQ-5D-5L is recommended in preference to the 3L version, however, further testing in other back pain populations together with additional measurement properties, including responsiveness to change, is recommended. | en_US |
dc.description.sponsorship | Oslo University Hospital, South Eastern Norway Regional Health Authority, and EXTRAfunds from the Norwegian Foundation for Health and Rehabilitation through the Norwegian Back Pain Association. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | BMC | en_US |
dc.relation.ispartofseries | Health and Quality of Life Outcomes;19:155 | |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | EQ-5D-3L | en_US |
dc.subject | EQ-5D-5L | en_US |
dc.subject | Low back pains | en_US |
dc.subject | Patient reported outcome measures | en_US |
dc.subject | PROMs | en_US |
dc.subject | Life qualities | en_US |
dc.subject | Validity | en_US |
dc.title | Evaluation of the EQ-5D-3L and 5L versions in low back pain patients | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | © The Author(s) 2021. | en_US |
dc.source.articlenumber | 155 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | https://doi.org/10.1186/s12955-021-01792-y | |
dc.identifier.cristin | 1915915 | |
dc.source.journal | Health and Quality of Life Outcomes | en_US |
dc.source.volume | 19 | en_US |
dc.source.pagenumber | 1-9 | en_US |
dc.relation.project | Norges forskningsråd: 262673 | en_US |