• Bidirectionality of antiseizure and antipsychotic treatment: A population-based study 

      Revdal, Eline; Morken, Gunnar; Bakken, Inger Johanne; Bråthen, Geir; Landmark, Cecilie Johannessen; Brodtkorb, Eylert (Epilepsy & Behavior;Volume 136, November 2022, 108911, Peer reviewed; Journal article, 2022-09-17)
      Purpose: To study the prevalence and directionality of comorbid epilepsy and psychosis in Norway. Methods: The Norwegian Prescription Database (NorPD) provided individual-based information on all antiseizure medications ...
    • Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018 

      Heger, Katrine; Skipsfjord, Julia; Kiselev, Yury; Burns, Margrete Larsen; Aaberg, Kari Modalsli; Johannessen, Svein Ivar; Skurtveit, Svetlana Ondrasova; Landmark, Cecilie Johannessen (Epilepsy Research;Volume 181, March 2022, 106872, Peer reviewed; Journal article, 2022-02-15)
      Background: The use of antiseizure medications (ASMs) in the pediatric population is poorly studied. The purpose of this study was to investigate changes in the use of ASMs in children and adolescents compared to adults, ...
    • Development and validation of a new non-disease-specific survey tool to assess self-reported adherence to medication 

      Larsen, Rønnaug; Pripp, Are Hugo; Krogstad, Tonje; Landmark, Cecilie Johannessen; Holm, Lene Berge (Frontiers in Pharmacology;Volume 13 - 2022, Peer reviewed; Journal article, 2022)
      Background: Patients’ non-adherence to medication affects both patients themselves and healthcare systems. Consequences include higher mortality, worsening of disease, patient injuries, and increased healthcare costs. Many ...
    • Effect and tolerability of perampanel in patients with drug-resistant epilepsy 

      Lossius, Ida Marie Bakke; Svendsen, Torleiv; Sødal, Hild Flatmark; Kjeldstadli, Kari Grandaunet; Lossius, Morten Ingvar; Nakken, Karl Otto; Landmark, Cecilie Johannessen (Epilepsy & Behavior;Volume 119, June 2021, 107965, Peer reviewed; Journal article, 2021-04-30)
      Objective: Perampanel is one of the most recently approved antiseizure medications. The aim of the present study was to assess clinical efficacy and tolerability, in combination with pharmacokinetic variability, of perampanel ...
    • Effectiveness and safety of everolimus treatment in patients with tuberous sclerosis complex in real-world clinical practice 

      Cockerell, Ine Tracey; Christensen, Jakob; Hoei-Hansen, Christina; Holst, Lotte; Frediksen, Mikkel G; Issa-Epe, Aart I.; Nedregaard, Bård; Solhoff, Ragnar Håkon; Heimdal, Ketil Riddervold; Landmark, Cecilie Johannessen; Lund, Beate Caroline Pernille; Nærland, Terje (Peer reviewed; Journal article, 2023)
      Background The randomised double‑blinded placebo‑controlled EXIST‑1–3 studies have showed everolimus effective with adverse effects reported as acceptable in treatment of symptoms in patients with tuberous sclerosis complex ...
    • Interactions between antiseizure medications and foods and drinks: A systematic review 

      Asadi-Pooya, Ali A.; Landmark, Cecilie Johannessen; Nafiseh Mirzaei, Damabi; Khatereh, Fazelian (Peer reviewed; Journal article, 2024)
      Antiseizure medications (ASMs) constitute the principal of treatment for patients with epilepsy, where long-term treatment is usually necessary. The purpose of this systematic review is to provide practical and useful ...
    • Lamotrigine effects on immune gene expression in larval zebrafish 

      Mochol, Monika; Whatmore, Paul; Taubøll, Erik; Landmark, Cecilie Johannessen; Ropstad, Erik; Svalheim, Sigrid; Fraser, Thomas (Epilepsy Research;Volume 178, December 2021, 106823, Peer reviewed; Journal article, 2021-11-26)
      Purpose: Despite growing evidence that neuroinflammation and pro-inflammatory cytokines are involved in the pathogenesis of seizures and epilepsy, this knowledge has not been incorporated in the proposed mechanism of action ...
    • Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring 

      Landmark, Cecilie Johannessen; Eyal, Sara; Burns, Margrete Larsen; Franco, Valentina; Johannessen, Svein Ivar (Journal article; Peer reviewed, 2023)
      Antiseizure medications (ASMs) are the cornerstone of treatment for patients with epilepsy. Several new ASMs have recently been introduced to the market, making it possible to better tailor the treatment of epilepsy, as ...
    • The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results 

      Landmark, Cecilie Johannessen; Potschka, Heidrun; Auvin, Stephane; Wilmhurst, Jo M.; Johannessen, Svein; Trenite, Dorothee K. N.; Wirrell, Elaine (Epilepsia;volume 62, issue 4, Peer reviewed; Journal article, 2021-02-27)
      Developmental and epileptic encephalopathies (DEEs) are among the most chal- lenging of all epilepsies to manage, given the exceedingly frequent and often severe seizure types, pharmacoresistance to conventional antiseizure ...
    • Therapeutic Salivary Monitoring of Perampanel in Patients with Epilepsy Using a Volumetric Absorptive Microsampling Technique 

      Palmisani, Michaela; Tartara, Elena; Landmark, Cecilie Johannessen; crema, Francesca; di Giorgis, valentina; Varsio, Constanza; Fattore, Cinzia; Russo, Emilio; franco, valentina (Peer reviewed; Journal article, 2023)
      The objective of this study was to validate a novel assay using the volumetric absorptive microsampling (VAMS) technique combined with liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) for the determination ...
    • Use of screening tools to assess comorbidities and adverse events in patients with epilepsy. A European Reference Network for Rare and Complex Epilepsies (EpiCARE) survey 

      Henning, Oliver Johannes; Alfstad, Kristin Åshild; Landmark, Cecilie Johannessen; Helmstadter, Cristoph; Lossius, Morten Ingvar; Skogan, Annette Holth (Peer reviewed; Journal article, 2022)
      Purpose As comorbidities can affect treatment decisions, quality of life, and prognosis in epilepsy, it is important that they are detected and addressed as soon as possible. Screening tools can help by rapidly assessing ...