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dc.contributor.authorIhle-Hansen, Hege
dc.contributor.authorLanghammer, Birgitta
dc.contributor.authorLydersen, Stian
dc.contributor.authorGunnes, Mari
dc.contributor.authorIndredavik, Bent
dc.contributor.authorAskim, Torunn
dc.date.accessioned2019-11-01T08:01:49Z
dc.date.accessioned2019-11-04T08:39:10Z
dc.date.available2019-11-01T08:01:49Z
dc.date.available2019-11-04T08:39:10Z
dc.date.issued2019-07-17
dc.identifier.citationIhle-Hansen, Langhammer, Lydersen, Gunnes, Indredavik, Askim. A physical activity intervention to prevent cognitive decline after stroke – Secondary results from the LAST (Life After Stroke) study. An 18-month randomised controlled trial.. Journal of Rehabilitation Medicine. 2019en
dc.identifier.issn1650-1977
dc.identifier.issn1650-1977
dc.identifier.issn1651-2081
dc.identifier.urihttps://hdl.handle.net/10642/7784
dc.description.abstractObjective: To examine the effects of individualized regular coaching and exercise on post-stroke cognitive and emotional function. Methods: The Life After STroke (LAST) study investigated the differences between intervention and care-as-usual between 3 and 21 months post-stroke. Outcome measures were the Trail Making Test (TMT) A and B, Mini Mental State Examination (MMSE), Hospital Anxiety and Depression Scale (HADS), and adherence to the intervention. Results: Of the 362 patients included in the study, 177 were assigned to the intervention. The mean age was 71.7 (SD 11.3) years and 39.5% were female. The adjusted mean difference between groups for TMT A was 8.54 (CI 0.7 to 16.3), p = 0.032, for TMT B 8.6 (CI –16.5 to 33.6), p = 0.50, for MMSE –0.1 (CI –0.8 to 0. 6), p = 0.77, for HADS A –0.2 (CI –0.9 to 0.5), p = 0.56 and for HADS D –0.1 (CI –0.7 to 0.5), p = 0.76). A higher level of adherence to the intervention was significantly associated with increased MMSE (B = 0.030 (CI 0.005–0.055), p = 0.020) Conclusion: No clinically relevant effects on cognitive or emotional function were found of individualized regular coaching for physical activity and exercise. However, increased adherence to the intervention was associated with improved cognitive function.en
dc.description.sponsorshipThe LAST study was funded by Norwegian Research Council, Liaison Committee between Central Norway Regional Health Authority and Norwegian University of Science and Technology (NTNU), Joint Research Committee between St Olav’s Hospital and NTNU, Norwegian Fund for Postgraduate Training in Physiotherapy, and Stroke Unit Research Fund at St Olav’s Hospital.en
dc.language.isoenen
dc.publisherFoundation for Rehabilitation Informationen
dc.relation.ispartofseriesJournal of Rehabilitation Medicine;Vol 51, Issue 9
dc.rightsThis is an open access article under the CC BY-NC license. All articles are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectStrokesen
dc.subjectInterventionsen
dc.subjectPhysical activitiesen
dc.subjectCognitionen
dc.titleA physical activity intervention to prevent cognitive decline after stroke – Secondary results from the LAST (Life After Stroke) study. An 18-month randomised controlled trial.en
dc.typeJournal articleen
dc.typePeer revieweden
dc.date.updated2019-11-01T08:01:49Z
dc.description.versionpublishedVersionen
dc.identifier.doihttps://dx.doi.org/10.2340/16501977-2588
dc.identifier.cristin1726996
dc.source.journalJournal of Rehabilitation Medicine


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This is an open access article under the CC BY-NC license.
All articles are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Except where otherwise noted, this item's license is described as This is an open access article under the CC BY-NC license. All articles are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.