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dc.contributor.authorEggemoen, Åse Ruth
dc.contributor.authorJenum, Anne Karen
dc.contributor.authorMdala, Ibrahimu
dc.contributor.authorKnutsen, Kirsten Irene Valebjørg
dc.contributor.authorLagerløv, Per
dc.contributor.authorSletner, Line
dc.date.accessioned2019-07-12T07:50:42Z
dc.date.available2019-07-12T07:50:42Z
dc.date.issued2017-04-14
dc.identifier.citationEggemoen, Å. R., Jenum, A. K., Mdala, I., Knutsen, K. V., Lagerløv, P., & Sletner, L. (2017). Vitamin D levels during pregnancy and associations with birth weight and body composition of the newborn: a longitudinal multiethnic population-based study. British Journal of Nutrition, 117(7), 985-993.en
dc.identifier.issn0007-1145
dc.identifier.urihttps://hdl.handle.net/10642/7277
dc.description.abstractWe investigated associations between serum 25-hydroxyvitamin D (25(OH)D) in pregnancy and birth weight and other neonatal anthropometric measures. The present study was a population-based, multiethnic cohort study of 719 pregnant women (59 % ethnic minorities) in Oslo, Norway, delivering a singleton neonate at term and with birth weight measurements. In a representative sample, anthropometric measurements were taken. Maternal 25(OH)D was measured at gestational weeks 15 and 28. Women with 25(OH)D <37 nmol/l were recommended vitamin D3 supplementation. Separate linear regression analyses were performed to model the associations between 25(OH)D and each of the outcomes: birth weight, crown–heel length, head circumference, abdominal circumference, sum of skinfolds, mid-upper arm circumference and ponderal index. In early pregnancy, 51 % of the women were vitamin D deficient (25(OH)D<50 nmol/l). In univariate analyses and in models adjusting for maternal age, parity, education, prepregnancy BMI, season, gestational age and neonate sex, maternal 25(OH)D was significantly associated with birth weight, head circumference, abdominal circumference and ponderal index (P<0·05 for all), when used as a continuous variable and categorised (consistently low, consistently high, increasing and decreasing level). However, after adjusting for ethnicity, 25(OH)D was no longer associated with any of the outcomes. Sex-specific associations for abdominal circumference and sum of skinfolds were found (P for interaction<0·05). In conclusion, in a multiethnic cohort of pregnant women with high prevalence of vitamin D deficiency, we found no independent relation between maternal vitamin D levels and any of the neonatal anthropometric measures, and the strong association between ethnicity and neonatal outcomes was not affected by maternal vitamin D status.en
dc.language.isoenen
dc.publisherCambridge University Pressen
dc.relation.ispartofseriesBritish Journal of Nutrition;117(7)
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States This is an open access article, originally published at https://doi.org/10.1017/S000711451700068Xen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectVDP::Medisinske Fag: 700en
dc.subjectArtikkelen
dc.titleVitamin D levels during pregnancy and associations with birth weight and body composition of the newborn: A longitudinal multiethnic population-based studyen
dc.typeJournal articleen
dc.typePeer revieweden
dc.description.versionpublishedVersionen
dc.identifier.doihttps://doi.org/10.1017/S000711451700068X
dc.identifier.cristin1486909


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Attribution-NonCommercial-NoDerivs 3.0 United States
This is an open access article, originally published at https://doi.org/10.1017/S000711451700068X
Med mindre annet er angitt, så er denne innførselen lisensiert som Attribution-NonCommercial-NoDerivs 3.0 United States This is an open access article, originally published at https://doi.org/10.1017/S000711451700068X