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dc.contributor.authorPallesen, Hanne
dc.contributor.authorBjerk, Maria
dc.contributor.authorRoer Pedersen, Asger
dc.contributor.authorFeldbæk Nielsen, Jørgen
dc.contributor.authorEvald, Lars
dc.date.accessioned2019-04-24T19:48:51Z
dc.date.accessioned2019-05-27T06:58:47Z
dc.date.available2019-04-24T19:48:51Z
dc.date.available2019-05-27T06:58:47Z
dc.date.issued2019-04-22
dc.identifier.citationPallesen H, Bjerk M, Roer Pedersen, Feldbæk Nielsen J, Evald L. The Effects of High-Intensity Aerobic Exercise on Cognitive Performance After Stroke: A Pilot Randomised Controlled Trial. Journal of central nervous system disease. 2019;11:1-10en
dc.identifier.issn1179-5735
dc.identifier.issn1179-5735
dc.identifier.urihttps://hdl.handle.net/10642/7162
dc.description.abstractBackground: Aerobic exercise is an effective treatment to improve aerobic capacity following stroke and might also improve cognitive impairments in sub-acute stroke survivors. The aim of the study was to assess the effect of high-intensity aerobic exercise on cognitive impairments in sub-acute stroke survivors. Methods: A pilot, randomised controlled trial on the effects of aerobic exercise on cognitive impairments of stroke patients in the sub-acute (1-3 months) phase was conducted. Thirty patients with moderate cognitive impairments (maximum score of 5 on at least two items on the cognitive subscales of the Functional Independence Measure [FIM]) were included in the study and randomly assigned to either the intervention group – performing high-intensity aerobic exercise (above 70% of maximum heart rate), or the control group – performing low-intensity aerobic exercise (below 60%). Patients in both groups exercised for 50 min twice a week for 4 weeks. Primary neuropsychological outcome: Trail Making Test B. Results: Thirty stroke patients completed the interventions. The results showed that the high-intensity group, compared with the low-intensity group, achieved significant improvements on Trail Making Test B, which assesses processing speed and divided attention (P = .04 after training and P = .01 at follow-up). However, the significant improvements on Trail Making Test B might relate to a ceiling effect in the control group. Conclusions: This study does not provide evidence to support that aerobic exercise can improve cognition in stroke survivors, even though significant improvement was revealed on the primary outcome in sub-acute stroke survivors following high-intensity aerobic exercise compared with low-intensity general exercise.en
dc.description.sponsorshipThe authors are most grateful for funding from HE Midt Research Fund and Danish Physiotherapists’ Research Fund.en
dc.language.isoenen
dc.publisherSAGEen
dc.relation.ispartofseriesJournal of Central Nervous System Disease;Volime 11
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectSub-acute stroke survivorsen
dc.subjectModerate cognitive impairmentsen
dc.subjectNeuropsychological assessmentsen
dc.subjectHigh-intensity trainingen
dc.titleThe Effects of High-Intensity Aerobic Exercise on Cognitive Performance After Stroke: A Pilot Randomised Controlled Trialen
dc.typeJournal articleen
dc.typePeer revieweden
dc.date.updated2019-04-24T19:48:51Z
dc.description.versionpublishedVersionen
dc.identifier.doihttps://dx.doi.org/10.1177%2F1179573519843493
dc.identifier.cristin1693772
dc.source.journalJournal of central nervous system disease
dc.subject.nsiVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Nevrologi: 752
dc.subject.nsiVDP::Midical sciences: 700::Clinical medical sciences: 750::Neurology: 752


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This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Med mindre annet er angitt, så er denne innførselen lisensiert som This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).