Browsing TKD - Institutt for informasjonsteknologi by Author "Ramstad, Ola Huse"

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Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna (Peer reviewed; Journal article, 2024)

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been widely linked to Parkinson’s disease, where the G2019S variant has been shown to contribute uniquely to both familial and sporadic forms of the disease. ...