Blar i TKD - Institutt for maskin, elektronikk og kjemi på forfatter "Berg-Hansen, Pål"

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    • Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis 

      Brune-Ingebretsen, Synne; Høgestøl, Einar August; de Rosbo, Nicole Kerlero; Berg-Hansen, Pål; Brunborg, Cathrine; Blennow, Kaj; Zetterberg, Henrik; Paul, Friedemann; Uccelli, Antonio; Villoslada, Pablo; Harbo, Hanne-Cathrin Flinstad; Berge, Tone (Peer reviewed; Journal article, 2023)
      Changes is lymphocyte subpopulations in peripheral blood have been proposed as biomarkers for evaluation of disease activity in multiple sclerosis (MS). Serum neurofilament light chain (sNfL) is a biomarker reflecting ...

    • Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients 

      Rhead, Brooke; Brorson, Ina Skaara; Berge, Tone; Adams, Cameron; Quach, Hong; Moen, Stine Marit; Berg-Hansen, Pål; Celius, Elisabeth Gulowsen; Sangurdekar, Dipen; Bronson, Paola G.; Lea, Rodney A.; Burnard, Sean; Maltby, Vicky E.; Scott, Rodney J; Lechner-Scott, Jeannette; Harbo, Hanne Flinstad; Bos, Steffan Daniel; Barcellos, Lisa F (PLoS ONE;13 (10): e0206511, Journal article; Journal article; Peer reviewed, 2018-10-31)
      DNA methylation is an epigenetic mark that is influenced by environmental factors and is associated with changes to gene expression and phenotypes. It may link environmental exposures to disease etiology or indicate important ...

    • No differential gene expression for CD4+ T cells of MS patients and healthy controls. 

      Brorson, Ina Skaara; Eriksson, Anna; Leikfoss, Ingvild Sørum; Celius, Elisabeth Gulowsen; Berg-Hansen, Pål; Barcellos, Lisa F.; Berge, Tone; Harbo, Hanne Flinstad; Bos, Steffan Daniel (Multiple Sclerosis Journal - Experimental, Translational and Clinical;Volume 5(2), Journal article; Peer reviewed, 2019-05-20)
      Background: Multiple sclerosis-associated genetic variants indicate that the adaptive immune system plays an important role in the risk of developing multiple sclerosis. It is currently not well understood how these multiple ...

    • Quantitative proteomic analyses of CD4+ and CD8+ T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls 

      Berge, Tone; Eriksson, Anna; Brorson, Ina Skaara; Høgestøl, Einar August; Berg-Hansen, Pål; Døskeland, Anne Marie Simonne; Mjaavatten, Olav; Bos, Steffan Daniel; Harbo, Hanne Flinstad; Berven, Frode (Clinical Proteomics;16, Article number: 19 (2019), Peer reviewed; Journal article, 2019-04-27)
      Background: Multiple sclerosis (MS) is an autoimmune, neuroinflammatory disease, with an unclear etiology. How‑ ever, T cells play a central role in the pathogenesis by crossing the blood–brain‑barrier, leading to inflammation ...