Blar i HV - Institutt for naturvitenskapelige helsefag på forfatter "Utheim, Tor Paaske"
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Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
Landsend, Erlend Christoffer Sommer; Olafsson, Jonatan; Lai, Xiaoran; Aass, Hans Christian Dalsbotten; Utheim, Tor Paaske (Journal of ophthalmology;Volume 2022, Article ID 5103231, Peer reviewed; Journal article, 2022-08-03)Purpose. To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease ... -
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients
Naqvi, Maria; Fineide, Fredrik; Utheim, Tor Paaske; Charnock, Colin (Peer reviewed; Journal article, 2024)Purpose: The purpose of this study was to investigate the ocular microbiome in individuals with dry eye disease and to identify features of their ocular microbiome of possible health and diagnostic significance. Methods: ... -
In-office thermal systems for the treatment of dry eye disease
Beining, Marie Wangen; Magnø, Morten Scherven; Moschowits, Emily; Olafsson, Jonatan; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Survey of ophthalmology;Volume 67, Issue 5, September–October 2022, Peer reviewed; Journal article, 2022-08-12)Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ... -
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Tashbayev, Behzod; Garen, Torhild Oddveig; Palm, Øyvind; Chen, Xiangjun; Herlofson, Bente Brokstad; Young Vik, Alix Rosslyn; Hove, Lene Hystad; Rykke, Morten; Singh, Preet Bano; Aqrawi, Lara Adnan; Utheim, Øygunn Aass; Utheim, Tor Paaske; Jensen, Janicke Cecilie Liaaen (Scientific Reports;10, Article number: 2063 (2020), Journal article; Peer reviewed, 2020-02-07)Understanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral ... -
A Preservative-Free Approach – Effects on Dry Eye Signs and Symptoms After Cataract Surgery
Jensen, Per Graae; Nilsen, Christian; Gundersen, Morten; Gundersen, Kjell Gunnar; Potvin, Rick; Gazerani, Parisa; Chen, Xiangjun; Utheim, Tor Paaske; Utheim, Øygunn Aass (Peer reviewed; Journal article, 2024)Purpose: To compare the effect of treatment with preservative-free dexamethasone, NSAIDs and trehalose/hyaluronic acid eye drops with the preservative benzalkonium chloride containing dexamethasone and NSAIDs after cataract ... -
Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic
Graae Jensen, Per; Gundersen, Morten; Nilsen, Christian; Gundersen, Kjell Gunnar; Potvin, Rick; Gazerani, Parisa; Chen, Xiangjun; Utheim, Tor Paaske; Utheim, Øygunn Aass (Clinical Ophthalmology;, Peer reviewed; Journal article, 2023)Purpose: To determine the prevalence of dry eye disease (DED) in patients scheduled for cataract surgery in a Norwegian eye clinic. Patients and Methods: 218 patients scheduled for cataract surgery were examined for DED ... -
Stem cell function is conserved during shortterm storage of cultured epidermal cell sheets at 12°C
Ringstad, Håkon; Reppe, Sjur; Schøyen, Tine Hiorth; Tønseth, Kim Alexander; Utheim, Tor Paaske; Jackson, Catherine (PLOS ONE;15 (5): e0232270, Journal article; Peer reviewed, 2020-05-20)Transplantation of cultured epidermal cell sheets (CES) can be life-saving for patients with large area burns. CES have also been successfully used to regenerate eye and urethral epithelia in animal models. Short-term ... -
Tear metabolomics in dry eye disease: A review
Yazdani, Mazyar; Elgstøen, Katja B. Prestø; Rootwelt, Helge; Shahdafar, Aboulghassem; Utheim, Øygunn Aass; Utheim, Tor Paaske (International Journal of Molecular Sciences;Volume 20, Issue 15, Journal article; Peer reviewed, 2019-08-01)Dry eye disease (DED) is a multifactorial syndrome that can be caused by alteration in the quality or quantity of the precorneal tear film. It is considered one of the most common ocular conditions leading patients to seek ... -
The therapeutic benefits of nanoencapsulation in drug delivery to the anterior segment of the eye: A systematic review
Bandhari, Madhavi; Nguyen, Sanko; Yazdani, Mazyar; Utheim, Tor Paaske; Hagesæther, Ellen (Frontiers in Pharmacology;May 2022 | Volume 13 | Article 903519, Peer reviewed; Journal article, 2022-05-13)Background: Although numerous nanoparticle formulations have been developed for ocular administration, concerns are being raised about a possible mismatch between potential promises made by the field of nanoparticle research ... -
The Therapeutic Benefits of Nanoencapsulation in Drug Delivery to the Anterior Segment of the Eye: A Systematic Review
Bhandari, Madhavi; Nguyen, Sanko; Yazdani, Mazyar; Utheim, Tor Paaske; Hagesæther, Ellen (Frontiers in Pharmacology;May 2022 | Volume 13 | Article 903519, Peer reviewed; Journal article, 2022)Background: Although numerous nanoparticle formulations have been developed for ocular administration, concerns are being raised about a possible mismatch between potential promises made by the field of nanoparticle research ... -
Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen; Yazdani, Mazyar; Lagali, Neil Satish; Vitelli, Valeria; Dartt, Darlene Ann; Chen, Xiangjun (Scientific Reports;10, Article number: 5542 (2020), Journal article; Peer reviewed, 2020-03-26)The prevalence of dry eye disease is high worldwide and poses a great burden on patients’ daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is ...