Blar i HV - Institutt for naturvitenskapelige helsefag på forfatter "Ambur, Ole Herman"

Viser treff 1-10 av 10

    • The alginate polymer OligoG alters susceptibility of biofilm-embedded non-typeable Haemophilus influenzae to ampicillin and ciprofloxacin 

      Marienborg, Kaja; Ambur, Ole Herman; Økstad, Ole Andreas; Skaare, Dagfinn (Peer reviewed; Journal article, 2023)
      Objectives Treatment of respiratory infections with non-typeable Haemophilus influenzae (NTHi) in COPD patients is complicated by biofilm formation, protecting the bacteria against the hosts’ immune response and antibiotics. ...

    • The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants 

      Kværner, Ane Sørlie; Birkeland, Einar Elvbakken; Bucher-Johannessen, Cecilie; Vinberg, Elina; Nordby, Jan Inge; Kangas, Harri; Bemanian, Vahid; Ellonen, Pekka; Botteri, Edoardo; Natvig, Erik; Rognes, Torbjørn; Hovig, Eivind; Lyle, Robert; Ambur, Ole Herman; de Vos, Willem M.; Bultman, Scott J; Hjartåker, Anette; Landberg, Rikard; Song, Mingyang; Blix, Hege Salvesen; Ursin, Giske; Randel, Kristin Ranheim; de Lange, Thomas; Hoff, Geir; Holme, Øyvind; Berstad, Paula; Rounge, Trine Ballestad (BMC Cancer;21, Article number: 930 (2021), Peer reviewed; Journal article, 2021-08-18)
      Background: Colorectal cancer (CRC) screening reduces CRC incidence and mortality. However, current screening methods are either hampered by invasiveness or suboptimal performance, limiting their effectiveness as primary ...

    • A genomic view of experimental intra- and interspecies transformation of a rifampicin resistance allele into Neisseria meningitidis 

      Alfsnes, Kristian; Frye, Stephan Alfons; Eriksson, JE; Tonjum, Tone; Eldholm, Vegard; Brynildsrud, Ola Brønstad; Bohlin, Jon; Harrison, OB; Hood, D; Maiden, Martin C.J.; Ambur, Ole Herman (Microbial Genomics;, Journal article; Peer reviewed, 2018-09-25)
      The spread of antibiotic resistance within and between different bacterial populations is a major health problem on a global scale. The identification of genetic transformation in genomic data from Neisseria meningitidis, ...

    • HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization 

      Meisal, Roger; Rounge, Trine Ballestad; Christiansen, Irene Kraus; Eieland, Alexander Kirkeby; Worren, Merete Molton; Molden, Tor; Kommedal, Øyvind; Hovig, Eivind; Leegaard, Truls Michael; Ambur, Ole Herman (Journal article; Peer reviewed, 2017)
      Sensitive and specific genotyping of human papillomaviruses (HPVs) is important for population-based surveillance of carcinogenic HPV types and for monitoring vaccine effectiveness. Here we compare HPV genotyping by Next ...

    • HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples 

      Lagström, Sonja; Løvstad, Alexander H; Umu, Sinan Uğur; Ambur, Ole Herman; Nygård, Mari; Rounge, Trine Ballestad; Christiansen, Irene Kraus (Tumour Virus Research;Volume 12, December 2021, 200221, Peer reviewed; Journal article, 2021-07-14)
      Human papillomavirus (HPV) 16 and 18 are the most predominant types in cervical cancer. Only a small fraction of HPV infections progress to cancer, indicating that additional factors and genomic events contribute to the ...

    • HPV16 whole genome minority variants in persistent infections from young Dutch women 

      Lagström, Sonja; van der Weele, Pascal; Rounge, Trine Ballestad; Christiansen, Irene Kraus; King, Audrey; Ambur, Ole Herman (Journal of Clinical Virology;Volume 119, October 2019, Journal article; Peer reviewed, 2019-08-09)
      Background: Chronic infections by one of the oncogenic human papillomaviruses (HPVs) are responsible for near 5% of the global cancer burden and HPV16 is the type most often found in cancers. HPV genomes displayunexpected ...

    • Intra-host sequence variability in human papillomavirus 

      Mandishora, Racheal Shamiso Dube; Gjøtterud, Kristina Stormo; Lagström, Sonja; Stray-Pedersen, Babill; Duri, Kerina; Chin'ombe, Nyasha; Nygård, Mari; Christiansen, Irene Kraus; Ambur, Ole Herman; Chirenje, Mike Zvavahera; Rounge, Trine Ballestad (Papillomavirus Research. The Journal of HPV and other Small DNA Tumor Viruses;Volume 5, June 2018, Journal article; Peer reviewed, 2018-04-30)
      Human papillomaviruses (HPVs) co-evolve slowly with the human host and each HPV genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype variants within samples, and their association to ...

    • Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping 

      Mandishora, Racheal S. Dube; Rounge, Trine Ballestad; Fitzpatrick, Megan; Christiansen, Hanne Irene Kraus; Ambur, Ole Herman; Lagström, Sonja; Stray-Pedersen, Babill; Tommasino, Massimo; Palefsky, Joel; Chirenje, Zvavahera M. (PLOS ONE;16 (4): e0250426, Peer reviewed; Journal article, 2021-04-26)
      Background & aim: Women with HIV/HPV coinfection and cervical lesions are at increased risk of developing HPV related anal cancer. Self-collection of anal swabs may facilitate HPV molecular testing in anal cancer screening, ...

    • Substantial Decline in Prevalence of Vaccine-Type and Nonvaccine-Type Human Papillomavirus (HPV) in Vaccinated and Unvaccinated Girls 5 Years After Implementing HPV Vaccine in Norway 

      Feiring, Berit; Laake, Ida; Christiansen, Irene Kraus; Hansen, Mona Lindsethmo; Stålcrantz, Jeanette; Ambur, Ole Herman; Magnus, Per; Jonassen, Christine M; Trogstad, Lill (Journal of Infectious Diseases;, Journal article; Peer reviewed, 2018-07-16)
      Background: In 2009, quadrivalent human papillomavirus (HPV) vaccine was introduced in a school-based single-cohort program targeting 12-year-old girls in Norway. We estimated the impact of the Norwegian HPV immunization ...

    • TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration 

      Lagström, Sonja; Umu, Sinan Uğur; Lepistö, Maija; Ellonen, Pekka; Meisal, Roger; Christiansen, Irene Kraus; Ambur, Ole Herman; Rounge, Trine Ballestad (Scientific Reports;9, Article number: 524 (2019), Journal article; Peer reviewed, 2018-11-26)
      HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effective sequencing ...