• Hb Aalesund (HBA2: c.400_406delAGCACCG), an Unstable α-Globin Variant Found in a Norwegian Patient Causing Moderate Hemolytic Anemia and Falsely High Hb A1c Using Ion Exchange High Performance Liquid Chromatography. 

      Grimholt, Runa Marie; Fjeld, Bente; Selsås, Hilde; Schwettmann, Lutz; Klingenberg, Olav (Hemoglobin;Volume 43, Issue 2, Journal article; Peer reviewed, 2019-04-03)
      A new unstable hemoglobin (Hb) variant, named Hb Aalesund, was detected during Hb A1c measurement in a patient with a nearly compensated hemolytic anemia. Sequencing of the α-globin genes revealed a 7 bp deletion in exon ...
    • Health-related quality of life in adolescents with persistent pain and the mediating role of self-efficacy: a cross-sectional study 

      Grasaas, Erik; Helseth, Sølvi; Fegran, Liv; Stinson, Jennifer; Småstuen, Milada Cvancarova; Haraldstad, Kristin (Health and Quality of Life Outcomes;18, Article number: 19 (2020), Journal article; Peer reviewed, 2020-01-30)
      Background: Persistent pain has a high prevalence among adolescents. Pain has been shown to reduce all aspects of the adolescent’s health-related quality of life (HRQOL). In adult patients with pain, self-efficacy has ...
    • Health‑related quality of life is strongly associated with self‑efficacy, self‑esteem, loneliness, and stress in 14–15‑year‑old adolescents: a cross‑sectional study 

      Mikkelsen, Hilde Elisabeth Timenes; Haraldstad, Kristin; Helseth, Sølvi; Skarstein, Siv; Småstuen, Milada Cvancarova; Rohde, Gudrun E. (Health and Quality of Life Outcomes;18, Article number: 352 (2020), Journal article; Peer reviewed, 2020-11-02)
      Background: To enhance and better understand health-related quality of life (HRQOL) in adolescents, it is important to study factors associated with HRQOL. The present study aimed to assess possible associations between ...
    • HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization 

      Meisal, Roger; Rounge, Trine Ballestad; Christiansen, Irene Kraus; Eieland, Alexander Kirkeby; Worren, Merete Molton; Molden, Tor; Kommedal, Øyvind; Hovig, Eivind; Leegaard, Truls Michael; Ambur, Ole Herman (Journal article; Peer reviewed, 2017)
      Sensitive and specific genotyping of human papillomaviruses (HPVs) is important for population-based surveillance of carcinogenic HPV types and for monitoring vaccine effectiveness. Here we compare HPV genotyping by Next ...
    • HPV16 whole genome minority variants in persistent infections from young Dutch women 

      Lagström, Sonja; van der Weele, Pascal; Rounge, Trine Ballestad; Christiansen, Irene Kraus; King, Audrey; Ambur, Ole Herman (Journal of Clinical Virology;Volume 119, October 2019, Journal article; Peer reviewed, 2019-08-09)
      Background: Chronic infections by one of the oncogenic human papillomaviruses (HPVs) are responsible for near 5% of the global cancer burden and HPV16 is the type most often found in cancers. HPV genomes displayunexpected ...
    • Hva finnes på innsiden av kranarmaturer? 

      Charnock, Colin; Otterholt, Eli; Nordlie, Anne-Lise (Vann;, Journal article; Peer reviewed, 2012)
      Innsiden av vannkraner kommer i kontakt med både mikrober som er til stede i drikkevann og de som finnes på hender, matrester og i luften. En hypotese er at kranbiofilmer kan være tilholdssted for sykdomsfremkallende ...
    • Hvor robust er samsvaret mellom respondering på matching-to-sample tester og sorteringstester? 

      Bevolden, Kristiane Rustad; Arntzen, Erik (Norsk tidsskrift for atferdsanalyse;Nummer 2 (VINTER 2018), Journal article; Peer reviewed, 2018)
      Formålet med dette eksperimentet var å undersøke om samsvaret mellom resultatene på en matching-to-sample (MTS) test og sorteringstester også er gjeldende ved bruk en Many-to-One (MTO) treningsstruktur. Vi ønsket å gjøre ...
    • Hyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death. 

      Kloster, Martine Müller; Naderi, Elin Hallan; Carlsen, Harald; Blomhoff, Heidi Kiil; Naderi, Soheil (Molecular Cancer;10 (45), Journal article; Peer reviewed, 2011-04-21)
      With cAMP signaling having a profound inhibitory effect on DNA damage-induced apoptosis in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells, understanding how this signaling pathway affects the survival capacity ...
    • 'I try not to bother the residents too much' - the use of capillary blood glucose measurements in nursing homes 

      Andreassen, Lillan Mo; Granås, Anne Gerd; Sølvik, Una Ørvim; Kjome, Reidun Lisbet Skeide (Journal article; Peer reviewed, 2016)
      Background Capillary blood glucose measurements are regularly used for nursing home residents with diabetes. The usefulness of these measurements relies on clear indications for use, correct measurement techniques, ...
    • Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor 

      Litchfield, Kevin; Levy, Max; Orlando, Giulia; Loveday, Chey; Law, Philip J.; Migliorini, Gabriele; Holroyd, Amy; Broderick, Peter; Karlsson, Robert; Haugen, Trine B.; Kristiansen, Wenche; Nsengimana, Jérémie; Fenwick, Kerry; Assiotis, Ioannis; Kote-Jarai, Zsofia; Dunning, Alison M.; Muir, Kenneth; Peto, Julian; Eeles, Rosalind; Easton, Douglas F.; Dudakia, Darshna; Orr, Nick; Pashayan, Nora; Bishop, D. Timothy; Reid, Alison; Huddart, Robert A.; Shipley, Janet; Grotmol, Tom; Wiklund, Fredrik; Houlston, Richard S.; Turnbull, Clare (Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)
      Genome-wide association studies (GWAS) have transformed our understanding of testicular germ cell tumour (TGCT) susceptibility but much of the heritability remains unexplained. Here we report a new GWAS, a meta-analysis ...
    • Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits 

      O`Connell, Kevin; Smith, Robert Løvsletten; Athanasiu, Lavinia; Djurovic, Srdjan; Kringen, Marianne K.; Molden, Espen; Andreassen, Ole Andreas (Translational Psychiatry; 10, Article number: 198 (2020), Journal article; Peer reviewed, 2020-06-19)
      Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study (GWAS) of CLZ serum ...
    • Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection 

      Andreassen, Rune; Nardos, Woldemariam; Ine, Egeland; Oleg, Agafanov; Hilde, Sindre; Bjørn, Høyheim (Journal article; Peer reviewed, 2017)
      Background MicroRNAs (miRNAs) control multiple biological processes including the innate immune responses by negative post-transcriptional regulation of gene expression. As there were no studies on the role(s) of miRNAs ...
    • Imaging in Lyme neuroborreliosis 

      Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Paulsen, Else Quist; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Elsais, Ahmed; Nygaard, Gro Owren; Lorentzen, Åslaug Rudjord; Harbo, Hanne Flinstad; Beyer, Mona K. (Insight into Imaging;October 2018, Volume 9, Issue 5, Journal article; Peer reviewed, 2018-09-04)
      Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ...
    • Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance 

      Aalen, John; Donal, Erwan; Larsen, Camilla Kjellstad; Duchenne, Jürgen; Lederlin, Mathieu; Cvijic, Marta; Hubert, Arnaud; Voros, Gabor; Leclercq, Christophe; Bogaert, Jan; Hopp, Einar; Fjeld, Jan Gunnar; Penicka, Martin; Linde, Cecilia; Aalen, Odd O.; Kongsgård, Erik; Galli, Elena; Voigt, Jens-Uwe; Smiseth, Otto A. (European Heart Journal;Volume 41, Issue 39, Journal article; Peer reviewed, 2020-09-11)
      Aims: Left ventricular (LV) failure in left bundle branch block is caused by loss of septal function and compensatory hyperfunction of the LV lateral wall (LW) which stimulates adverse remodelling. This study investigates ...
    • Impact of iodine concentration and scan parameters on image quality, contrast enhancement and radiation dose in thoracic CT 

      Solbak, Marian S.; Henning, Mette Karen; England, Andrew; Martinsen, Anne Catrine Trægde; Aaløkken, Trond M; Johansen, Safora (European Radiology Experimental;4, Article number: 57 (2020), Journal article; Peer reviewed, 2020-09-11)
      Background: We investigated the impact of varying contrast medium (CM) densities and x-ray tube potentials on contrast enhancement (CE), image quality and radiation dose in thoracic computed tomography (CT) using two ...
    • The impact of operator training on the accuracy of DXA lumbar spine analysis 

      McDermott, Eilish; Dutruit, Y.; Jeanneret-Grosjean, C; Koen, K; McPhilomy, C; Snelders, F; Stensrud, Kristin; Tcacenco, A; Aandahl, Ingrid-Jannicke (OPTIMAX 2018 - a focus on education in radiology;, Chapter; Peer reviewed, 2019)
      Introduction: This study involving Dual-energy X-ray Absorptiometry (DXA) spine images investigated the effectiveness of an additional training session compared to basic instruction provided by the scanner manufacturer ...
    • The impact of pitch values on image quality and radiation dose in an abdominal adult phantom using CT 

      Lança, Luis; Barros, Pietro; Løvlien, Ine M.; Derech, Rodrigo D’Agostini; Higgins, Daniel; Kleiker, Marjolein; McNally, Kevin; Thevenaz, Manon; Hogg, Peter; Liardet, Sebastien (Chapter; Peer reviewed, 2017)
      Purpose: To identify the impact of different pitch values on image quality and effective radiation dose for axial and coronal plane in abdominal adult CT. Methods and materials: Three scans were conducted on an abdominal ...
    • Impact of the anode heel effect on image quality and effective dose for AP pelvis: a pilot study 

      Buissink, Carst; Bowdler, Matt; Abdullah, A; Al-Murshedi, S; Custódio, S; Huhn, Andrea; Jorge, Jose; Ali, Mohammed; Peters, Annastagia Lily; Robin, Rey Yohan; Urdahl, Therese Kristin; Hogg, Peter (Chapter; Peer reviewed, 2017)
      Purpose: Using phantoms, this pilot study aims to outline a method and generate initial data to determine whether the anode heel effect has an impact on image quality and the effective dose. Methods and Materials: A ...
    • Implications of stx loss for clinical diagnostics of Shiga toxin-producing Escherichia coli 

      Senthakumaran, Thulasika; Brandal, Lin Cathrine T.; Lindstedt, Bjørn-Arne; Jørgensen, Silje Bakken; Charnock, Colin; Tunsjø, Hege (European Journal of Clinical Microbiology and Infectious Diseases;Volume 37, Issue 12, Journal article; Journal article; Peer reviewed, 2018-09-28)
      The dynamics related to the loss of stx genes from Shiga toxin-producing Escherichia coli remain unclear. Current diagnostic procedures have shortcomings in the detection and identification of STEC. This is partly owing ...
    • Increased glycolysis and higher lactate production in hyperglycemic myotubes 

      Lund, Jenny; Ouwens, DM; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege; Aas, Vigdis (Cells;Volume 8, Issue 9, Journal article; Peer reviewed, 2019-09-18)
      Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial ...