• DNA-ekstraksjon: Mengde er ikke synonymt med mangfold 

      Tunsjø, Hege; Bemanian, Vahid; Noone, John Christopher (Journal article; Peer reviewed, 2017)
      For å oppnå gode og representative resultater i molekylærgenetiske analyser, er det viktig at nukleinsyrene som benyttes er av tilstrekkelig kvalitet. Som en del av en større studie om kolerektal kreft, var målet å ...
    • Does the line-to-line cementing technique of the femoral stem create an adequate cement mantle? 

      Sevaldsen, Kirsti; Husby, Otto Schnell; Lian, Øystein Bjerkestrand; Husby, Vigdis Schnell (HIP International;, Peer reviewed; Journal article, 2020-06-18)
      Background: The line-to-line cementing technique is proposed to create a press-fit in the femoral canal, which is contrary to modern cementing techniques. The term ‘French paradox’ has been used to describe the acceptable ...
    • Dose Distribution in the Heart and Cardiac Chambers Following 4-field Radiation Therapy of Breast Cancer: a Retrospective Study 

      Johansen, Sefora; Tjessem, Kristin Holm; Fosså, Kristian; Bosse, Gerhard; Danielsen, Turi; Malinen, Erik; Fosså, Sophie Dorothea (Breast cancer: basic and clinical research;7, Journal article; Peer reviewed, 2013-03-20)
      Purpose: To evaluate cardiac doses in breast cancer patients with stage II/III treated with 4-field radiotherapy based on computed tomography (CT) dose planning. Methods and Materials: Based on archived CT images, whole ...
    • Drug interactions involving the new second- and third-generation antiepileptic drugs 

      Landmark, Cecilie Johannessen; Patsalos, Philip N. (Expert Review of Neurotherapeutics;10 (1), Academic article, 2010-01)
      During the period 1989-2009, 14 new antiepileptic drugs (AEDs) were licensed for clinical use and these can be subdivided into new second- and third-generation AEDs. The second-generation AEDs comprise felbamate, gabapentin, ...
    • Effect and tolerability of perampanel in patients with drug-resistant epilepsy 

      Lossius, Ida Marie Bakke; Svendsen, Torleiv; Sødal, Hild Flatmark; Kjeldstadli, Kari Grandaunet; Lossius, Morten Ingvar; Nakken, Karl Otto; Landmark, Cecilie Johannessen (Epilepsy & Behavior;Volume 119, June 2021, 107965, Peer reviewed; Journal article, 2021-04-30)
      Objective: Perampanel is one of the most recently approved antiseizure medications. The aim of the present study was to assess clinical efficacy and tolerability, in combination with pharmacokinetic variability, of perampanel ...
    • Effect of a one-year personalized intensive dietary intervention on body composition in colorectal cancer patients: Results from a randomized controlled trial 

      Alavi, Dena Treider; Henriksen, Hege Berg; Lauritzen, Peter Mæhre; Zucknick, Manuela; Bøhn, Siv Kjølsrud; Henriksen, Christine; Paur, Ingvild; Smeland, Sigbjørn; Blomhoff, Rune (Peer reviewed; Journal article, 2023)
      Background and aims Changes in body composition may affect colorectal cancer (CRC) patient's risk of cancer recurrence, secondary cancer, and other chronic diseases. The suggested interventions for changes in body composition ...
    • The Effect of Cancer Patients’ and TheirFamily Caregivers’ Physical and EmotionalSymptoms on Caregiver Burden 

      Johansen, Safora; Småstuen, Milada C; Ruland, Cornelia (Journal article; Peer reviewed, 2017)
      BACKGROUND: Although there is significant evidence that the family caregivers (FCs) of cancer patients can experience significant caregiver burden and symptoms, less is known about the relationships between FCs and ...
    • Effect of CYP2D6 genotype on duloxetine serum concentration 

      Hole, Kristine; Gangsø, Sofie; Jensstuen, Åse Tonette; Ormøy, Hanne Holte; Paulsen, Maren; Molden, Espen; Haslemo, Tore (Peer reviewed; Journal article, 2023)
      Duloxetine is metabolized by cytochrome P450 (CYP)1A2 and CYP2D6. The aim of this study was to investigate the effect of the CYP2D6 genotype on duloxetine serum concentration adjusting for age and sex. Patients were included ...
    • Effect of exercise interventions in the early phase to improve physical function after hip fracture – A systematic review and meta-analysis 

      Beckmann, Monica; Bruun-Olsen, Vigdis; Pripp, Are Hugo; Bergland, Astrid; Smith, Toby; Heiberg, Kristi Elisabeth (Physiotherapy;Volume 108, Journal article; Peer reviewed, 2020-05-19)
      Background The efficacy of exercise interventions in the early recovery phase, i.e. started within the first three months after hip fracture, has been poorly studied compared to prolonged exercise interventions. Objective ...
    • The effect of new formulas for lean body mass on lean- body-mass-normalized SUV in oncologic 18F-FDG PET/CT 

      Halsne, Trygve; Müller, Ebba Gløersen; Spiten, Ann-Eli; Sherwani, Alexander Gul; Mikalsen, Lars Tore G; Rootwelt-Revheim, Mona-Elisabeth; Stokke, Caroline (Journal of Nuclear Medicine Technology;Vol. 46, No. 3, Journal article; Peer reviewed, 2018-03-28)
      Due to better precision and intercompatibility, the use of lean body mass (LBM) as mass estimate in the calculation of standardized uptake values (SUV) has become more common in research and clinical studies today. Thus, ...
    • The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells 

      Tingstad, Ragna Husby; Norheim, Frode Amador; Haugen, Fred; Feng, Yuan Zeng; Tunsjø, Hege; Thoresen, G. Hege; Rustan, Arild Christian; Charnock, Colin; Aas, Vigdis (Scientific Reports;11, Article number: 24219 (2021), Peer reviewed; Journal article, 2021-12-20)
      Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of ...
    • Effect of vestibular rehabilitation on change in health-related quality of life in patients with dizziness and balance problems after traumatic brain injury: A randomized controlled trial 

      Søberg, Helene Lundgaard; Hadzic-Andelic, Nada; Langhammer, Birgitta; Tamber, Anne-Lise; Bruusgaard, Kari A.; Kleffelgård, Ingerid (Peer reviewed; Journal article, 2021)
      This paper is the first to present results of a vestibular rehabilitation intervention study on changes in healthrelated quality of life in patients with dizziness and balance problems after mild-to-moderate traumatic brain ...
    • Effects of a Novel UGT2B Haplotype and UGT1A4*3 Allele Variants on Glucuronidation of Clozapine In vivo 

      Smith, Robert Løvsletten; Wollmann, Birgit Malene Tovik; Kausberg, Marianne; Mæland, Sondre; Tveito, Marit; O'Connell, Kevin Sean; Molden, Espen; Kringen, Marianne K. (Current drug metabolism;Volume 23, Issue 1, Peer reviewed; Journal article, 2022)
      Background: Glucuronidation is an important metabolic pathway of clozapine (CLZ), but the impact of various uridine 5'diphospho-glucuronosyltransferases (UGT) polymorphisms on the exposure and metabolism of CLZ in vivo is ...
    • The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up 

      Øiestad, Britt Elin; Årøen, Asbjørn; Røtterud, Jan H; Østerås, Nina; Jarstad, Even; Grotle, Margreth; Risberg, May Arna (Peer reviewed; Journal article, 2023)
      Objective: To evaluate the efficacy of strength exercise or aerobic exercise compared to usual care on knee-related quality of life (QoL) and knee function at 4 months and 1 year in individuals with knee osteoarthritis. ...
    • Electrical Pulse Stimulation of Cultured Human Skeletal Muscle Cells as an In Vitro Model of Exercise 

      Nikolić, Nataša; Bakke, Siril Skaret; Kase, Eili Tranheim; Rudberg, Ida; Halle, Ingeborg Flo; Rustan, Arild C.; Thoresen, G. Hege; Aas, Vigdis (PLoS ONE;7 (3), Peer reviewed; Journal article, 2012-03-22)
      Background and Aims Physical exercise leads to substantial adaptive responses in skeletal muscles and plays a central role in a healthy life style. Since exercise induces major systemic responses, underlying cellular ...
    • Electrical pulse stimulation of primary human skeletal muscle cells 

      Nikolic, Natasa; Aas, Vigdis (Methods in molecular biology;MIMB, volume 1889, Chapter; Journal article; Peer reviewed, 2018-10-27)
      Electrical pulse stimulation (EPS) is an in vitro method of inducing contractions in cultured skeletal muscle cells of human and animal origin. Motor neuron activation of muscle fibres can be replaced by applying EPS on ...
    • Epigenetics of Migraine 

      Gazerani, Parisa (Chapter; Peer reviewed, 2023)
      Genetics and the environment have both been demonstrated to take part in the pathogenesis of migraine. Studying the epigenetic mechanisms underlying migraine can facilitate the understanding of the disorder, its chronification, ...
    • Epilepsy and cannabidiol: a guide to treatment 

      Arizmanoglou, Alexis; Brandl, Ulrich; Cross, Helen; Gil-nagel, Antonio; Lagae, Lieven; Landmark, Cecilie Johannessen; Specchio, Nicola; Nabbout, Rima; Thiele, Elisabeth; Gubbay, Oliver (Epileptic Disorders;Volume 22, Issue 1, February 2020, Journal article; Peer reviewed, 2020-12-19)
      The growing interest in cannabidiol (CBD), specifically a pure form of CBD, as a treatment for epilepsy, among other conditions, is reflected in recent changes in legislation in some countries. Although there has been much ...
    • Er hygiene-protokollene i radiologiske avdelinger optimale for å hindre MRSA-smitte? 

      Boquist, Kajsa Pauline; Rudi, Nina Helen (Radiography Open;Vol 4 No 1 (2018), Journal article; Peer reviewed, 2018-06-21)
      Innledning: MRSA er en bakterie som er motstandsdyktig mot både penicillin og methicillin. Den er fryktet i norske helseinstitusjoner da den er vanskelig å behandle. Det er viktig å ha gode protokoller for generell hygiene, ...
    • The Evaluation of a Social Media Campaign to Increase COVID-19 Testing in Migrant Groups: Cluster Randomized Trial 

      Elgersma, Ingeborg Hess; Fretheim, Atle; Indseth, Thor; Munch, Anita Thorolvsen; Johannessen, Live Bøe; Hansen, Christine Engh (Journal of Medical Internet Research;Vol 24, No 3 (2022): March, Peer reviewed; Journal article, 2022-03-24)
      Background: A low test positivity rate is key to keeping the COVID-19 pandemic under control. Throughout the pandemic, several migrant groups in Norway have seen higher rates of confirmed COVID-19 and related hospitalizations, ...