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    • Competence for Natural Transformation Is Common among Clinical Strains of Resistant Acinetobacter spp 

      Domingues, Sara; Rosario, N; Candido, A; Neto, Daniela; Nielsen, Kaare Magne; Da Silva, Gabriela Jorge (Microorganisms;Volume 7, Issue 2, Journal article; Peer reviewed, 2019-01-24)
      Horizontal gene transfer events provide the basis for extensive dissemination of antimicrobial resistance traits between bacterial populations. Conjugation is considered to be the most frequent mechanism behind new resistance ...

    • Competence in Sports Pharmacy among Pharmacy Students in Norway 

      Dabrowska, Natalia; Malmberg, Lone; Hadis, Nejati; Bach Volle, Cecilie; Røssing Witzø, Maren; Yaman, Hatice; Gazerani, Parisa (Peer reviewed; Journal article, 2024)
      Pharmacists are competent to promote the proper use of medicines. According to the International Pharmaceutical Federation, pharmacists must develop competence in sports pharmacy and the contents of the World Anti-Doping ...

    • Complexity of drug substitutions caused by drug tenders: A mixed-methods study in Denmark 

      Klitgaard Larsen, Lina; Middelbo Outzen, Emilie; Gazerani, Parisa; Plet, Hanne (Peer reviewed; Journal article, 2021)
      Objective: The objective of this study was to investigate factors influencing the complexity of drug substitutions caused by drug tenders in a Danish hospital setting. Methods: A sequential explanatory mixed-methods approach ...

    • Complications, reoperations, readmissions, and length of hospital stay in 34 639 surgical cases of lumbar disc herniation 

      Fjeld, Olaf Randall; Grøvle, Lars; Helgeland, Jon; Småstuen, Milada Cvancarova; Solberg, Tore; Zwart, John-Anker; Grotle, Margreth (The Bone & Joint Journal;Volume 101-B, Issue 4 / April 2019, Journal article; Peer reviewed, 2019-03-31)
      Aims The aims of this study were to determine the rates of surgical complications, reoperations, and readmissions following herniated lumbar disc surgery, and to investigate the impact of sociodemographic factors and ...

    • Compression forces used in the Norwegian Breast Cancer Screening Program 

      Wåde, Gunvor Gipling; Moshina, Nataliia; Sebuødegård, Sofie; Hogg, Peter; Hofvind, Solveig (Journal article; Peer reviewed, 2017)
      Objective: Compression is used in mammography to reduce breast thickness, which is claimed to improve image quality and reduce radiation dose. In the Norwegian Breast Cancer Screening Program (NBCSP), the recommended ...

    • Conformational complexity of morphine and morphinum in the gas phase and in water. A DFT and MP2 study 

      Møllendal, Harald; Balcells, David; Eisenstein, Odile; Syversen, Linda; Suissa, Michal Rachel (RSC Advances;4(47), Journal article; Peer reviewed, 2014-05-23)
      The structural and conformational properties of morphine and protonated morphine (morphinum) in the gas phase and in water solution have been explored with quantum calculations. Fully optimized calculations using the cc-pVTZ ...

    • Construction and validation of a low cost paediatric pelvis phantom 

      Johansen, Safora; Hogg, Peter; Mohammad Ali, Ali; England, Andrew (European Journal of Radiology;Volume 108, November 2018, Journal article; Peer reviewed, 2018-09-14)
      PURPOSE: Imaging phantoms can be cost prohibitive, therefore a need exists to produce low cost alternatives which are fit for purpose. This paper describes the development and validation of a low cost paediatric pelvis ...

    • Contrast medium protocols in routine chest CT:a survey study 

      Henning, Mette Karen; Aaløkken, Trond M; Johansen, Safora (Peer reviewed; Journal article, 2021)
      Background Administration of contrast medium (CM) is an important image quality factor in computed tomography (CT) of the chest. There is no clear evidence or guidelines on CM strategies for chest CT, thus a consensus ...

    • Contribution of Central and Peripheral Glial Cells in the Development and Persistence of Itch: Therapeutic Implication of Glial Modulation 

      Gazerani, Parisa (Neuroglia;, Peer reviewed; Journal article, 2023)
      Chronic itch (CI) is an unpleasant skin sensation accompanied by an intense scratching desire that lasts 6 weeks or longer. Despite the high prevalence and negative impact on affected individuals and a huge healthcare ...

    • Contribution of Small Extracellular Vesicles from Schwann Cells and Satellite Glial Cells to Pain Processing 

      Gazerani, Parisa (Peer reviewed; Journal article, 2024)
      Extracellular vesicles (EVs), including exosomes and microvesicles, are membrane-bound particles released by cells into extracellular space. These vesicles carry various molecules, such as proteins and lipids, and can ...

    • Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes 

      Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria; Hjelmesæth, Jøran; Sandbu, Rune; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Jansson-Löfmark, Rasmus; Karlsson, Cecilia; Andersson, Shalini; Åsberg, Anders; Andersson, Tommy B.; Christensen, Hege Staaland (Journal of Pharmaceutical Sciences;Volume 110, Issue 1, Journal article; Peer reviewed, 2020-10-18)
      Obesity is associated with comorbidities of which pharmacological treatment is needed. Physiological changes associated with obesity may influence the pharmacokinetics of drugs, but the effect of body weight on drug ...

    • Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range 

      Kvitne, Kine Eide; Hole, Kristine; Krogstad, Veronica; Wollmann, Birgit Malene Tovik; Wegler, Christine; Johnson, Line Kristin; Hertel, Jens Kristoffer; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Sandbu, Rune; Hjelmesæth, Jøran Sture; Skovlund, Eva; Christensen, Hege; Jansson-Löfmark, Rasmus; Åsberg, Anders; Molden, Espen; Robertsen, Ida (European Journal of Clinical Pharmacology;Volume 78, issue 8, Peer reviewed; Journal article, 2022-06-01)
      Purpose Variability in cytochrome P450 3A4 (CYP3A4) metabolism is mainly caused by non-genetic factors, hence providing a need for accurate phenotype biomarkers. Although 4β-hydroxycholesterol (4βOHC) is a promising ...

    • Correlations between 68Ga]Ga-DOTA-TOC Uptake and Absorbed Dose from [177Lu]Lu-DOTA-TATE 

      Bruvoll, Ragnar Bjørn Watte; Blakkisrud, Johan; Mikalsen, Lars Tore Gyland; Connelly, James Pattrick; Stokke, Caroline (Journal article; Peer reviewed, 2023)
      Purpose: The aim of this paper was to investigate correlations between pre- therapeutic [68Ga]Ga-DOTA-TOC uptake and absorbed dose to tumours from therapy with [177Lu]Lu-DOTA- TATE. Methods: This retrospective study included ...

    • Cost differences between digital tomosynthesis and standard digital mammography in a breast cancer screening programme: results from the To-Be trial in Norway 

      Moger, Tron Anders; Swanson, Jayson O.; Holen, åsne Sørlien; Hanestad, Berit; Hofvind, Solveig (European Journal of Health Economics;Volume 20, pages 1261–1269 (2019), Journal article; Peer reviewed, 2019-07-31)
      Background: Several studies in Europe and the US have shown promising results favouring digital breast tomosynthesis compared to standard digital mammography (DM). However, the costs of implementing the technology in ...

    • The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants 

      Kværner, Ane Sørlie; Birkeland, Einar Elvbakken; Bucher-Johannessen, Cecilie; Vinberg, Elina; Nordby, Jan Inge; Kangas, Harri; Bemanian, Vahid; Ellonen, Pekka; Botteri, Edoardo; Natvig, Erik; Rognes, Torbjørn; Hovig, Eivind; Lyle, Robert; Ambur, Ole Herman; de Vos, Willem M.; Bultman, Scott J; Hjartåker, Anette; Landberg, Rikard; Song, Mingyang; Blix, Hege Salvesen; Ursin, Giske; Randel, Kristin Ranheim; de Lange, Thomas; Hoff, Geir; Holme, Øyvind; Berstad, Paula; Rounge, Trine Ballestad (BMC Cancer;21, Article number: 930 (2021), Peer reviewed; Journal article, 2021-08-18)
      Background: Colorectal cancer (CRC) screening reduces CRC incidence and mortality. However, current screening methods are either hampered by invasiveness or suboptimal performance, limiting their effectiveness as primary ...

    • Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance 

      Larsson, J; Andremont, A; Bengtsson-Palme, Johan; Koefoed Brandt, K; de Roda Husman, AM; Fagerstedt, P.; Flick, J; Flack, CF; Gaze, William H.; Kuroda, Masako; Kvint, K; Laxminarayan, R; Manaia, M; Nielsen, Kaare Magne; Plant, L; Ploy, MC; Segovia, P; Simonet, Pascal; Smalla, Kornelia; Snape, J; Topp, Edward; Van Hengel, AW; Verner-Jeffreys, DW; Virta, MPJ; Wellington, EM; Wernersson, AS (Environment International;Volume 117, Journal article; Peer reviewed, 2018-05-07)
      There is growing understanding that the environment plays an important role both in the transmission of antibiotic resistant pathogens and in their evolution. Accordingly, researchers and stakeholders world-wide seek to ...

    • Cross-national comparison of screening mammography accuracy measures in U.S., Norway, and Spain 

      Domingo, Laia; Hofvind, Solveig; Hubbard, Rebecca A.; Roman, Martha; Benkeser, David; Sala, Maria; Castells, Xavier (European radiology;, Journal article; Peer reviewed, 2015-11-11)
      Objective To compare accuracy measures for mammographic screening in Norway, Spain, and the US. Methods Information from women aged 50–69 years who underwent mammographic screening 1996–2009 in the US (898,418 ...

    • CT Density in Lung Cancer Patients After Radiotherapy Sensitized by Metoclopramide : A Subgroup Analysis of a Randomized Trial 

      Dale, Einar; Hårsaker, Vanja; Kristoffersen, Doris T.; Bruland, Øyvind; Olsen, Dag Rune (Strahlentherapie und Onkologie;186 (3), Journal article; Peer reviewed, 2010-02-22)
      Purpose: To investigate the lung tissue response measured with computed tomography (CT) after radiotherapy (RT) combined with metoclopramide. Patients and Methods: Patients with non-small cell lung cancer (tumor stage ...

    • Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients 

      Naqvi, Maria; Fineide, Fredrik; Utheim, Tor Paaske; Charnock, Colin (Peer reviewed; Journal article, 2024)
      Purpose: The purpose of this study was to investigate the ocular microbiome in individuals with dry eye disease and to identify features of their ocular microbiome of possible health and diagnostic significance. Methods: ...

    • A de novo Full-Length mRNA Transcriptome Generated From Hybrid-Corrected PacBio Long-Reads Improves the Transcript Annotation and Identifies Thousands of Novel Splice Variants in Atlantic Salmon 

      Ramberg, Sigmund; Bjørn, Høyheim; tone-kari, knutsdatter østbye; Andreassen, Rune (Frontiers in Genetics;April 2021 | Volume 12 | Article 656334, Peer reviewed; Journal article, 2021-04-27)
      Atlantic salmon (Salmo salar) is a major species produced in world aquaculture and an important vertebrate model organism for studying the process of rediploidization following whole genome duplication events (Ss4R, 80 ...