Browsing HV - Institutt for naturvitenskapelige helsefag by Title
Now showing items 106-125 of 444
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Discovery of miRNAs and Their Corresponding miRNA Genes in Atlantic Cod(Gadus morhua): Use of Stable miRNAs as Reference Genes Reveals Subgroups of miRNAs That Are Highly Expressed in Particular Organs
(Peer reviewed; Journal article; Journal article, 2016-04-29)Background Atlantic cod (Gadus morhua) is among the economically most important species in the northern Atlantic Ocean and a model species for studying development of the immune system in vertebrates. MicroRNAs (miRNAs) ... -
Disiplinfagenes plass i profesjonsutdanningene
(Peer reviewed; Chapter, 2011) -
A Dispositional Account of Causation: Implications for the Biological Sciences
(Chapter; Peer reviewed, 2024)Scientific approaches inspired by the Humean concept of causation has left an epistemic gap between the causal knowledge gained in the idealised context of the lab and the real-life contexts to which the results are applied. ... -
Dispositions and Causality Assessment in Pharmacovigilance: Proposing the Dx3 Approach for Assessing Causality with Small Data Sets
(Pharmaceutical Medicine;Volume 36, issue 3, Peer reviewed; Journal article, 2022)A new approach is proposed for assessing causality in pharmacovigilance. The Dx3 approach is designed to qualitatively evaluate three types of dispositions when assessing whether a particular medicine has or could have ... -
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation
(Frontiers in Physiology;, Peer reviewed; Journal article, 2023)Lifestyle disorders like obesity, type 2 diabetes (T2D), and cardiovascular diseases can be prevented and treated by regular physical activity. During exercise, skeletal muscles release signaling factors that communicate ... -
Diversion and phylogenetic relatedness of filterable bacteria from Norwegian tap and bottled waters
(Journal of Water & Health;Volume 17 Issue 2, Journal article; Peer reviewed, 2019-02-22)Numerous articles have documented the existence of filterable bacteria. Where filtration is the chosen method of sterilization for medicinal or media components, these bacteria will by definition render products non-sterile. ... -
A DNA profiling system for conservation management of Kamchatka brown bear (Ursus arctos piscator); population data and system performance from 16 autosomal STRs
(Forensic Science International: Animals and Environments;, Peer reviewed; Journal article, 2024)Despite the high density of brown bears (Ursus arctos piscator) on the Kamchatka peninsula their genetic variation has not been studied by STR analysis. Our aim was, therefore, to provide population data from the Kamchatka ... -
DNA-ekstraksjon: Mengde er ikke synonymt med mangfold
(Journal article; Peer reviewed, 2017)For å oppnå gode og representative resultater i molekylærgenetiske analyser, er det viktig at nukleinsyrene som benyttes er av tilstrekkelig kvalitet. Som en del av en større studie om kolerektal kreft, var målet å ... -
Does in vitro hemolysis affect measurements of plasma apixaban concentration by UPLC-MS and anti-Xa assay?
(Peer reviewed; Journal article, 2024)Introduction: Hemolytic interference may impact various laboratory tests, including coagulation analyses. Apixaban is the most commonly used direct oral anticoagulant in Norway, and there is lacking knowledge on how ... -
Does the line-to-line cementing technique of the femoral stem create an adequate cement mantle?
(HIP International;, Peer reviewed; Journal article, 2020-06-18)Background: The line-to-line cementing technique is proposed to create a press-fit in the femoral canal, which is contrary to modern cementing techniques. The term ‘French paradox’ has been used to describe the acceptable ... -
Dose Distribution in the Heart and Cardiac Chambers Following 4-field Radiation Therapy of Breast Cancer: a Retrospective Study
(Breast cancer: basic and clinical research;7, Journal article; Peer reviewed, 2013-03-20)Purpose: To evaluate cardiac doses in breast cancer patients with stage II/III treated with 4-field radiotherapy based on computed tomography (CT) dose planning. Methods and Materials: Based on archived CT images, whole ... -
Drug interactions involving the new second- and third-generation antiepileptic drugs
(Expert Review of Neurotherapeutics;10 (1), Academic article, 2010-01)During the period 1989-2009, 14 new antiepileptic drugs (AEDs) were licensed for clinical use and these can be subdivided into new second- and third-generation AEDs. The second-generation AEDs comprise felbamate, gabapentin, ... -
Effect and tolerability of perampanel in patients with drug-resistant epilepsy
(Epilepsy & Behavior;Volume 119, June 2021, 107965, Peer reviewed; Journal article, 2021-04-30)Objective: Perampanel is one of the most recently approved antiseizure medications. The aim of the present study was to assess clinical efficacy and tolerability, in combination with pharmacokinetic variability, of perampanel ... -
Effect of a one-year personalized intensive dietary intervention on body composition in colorectal cancer patients: Results from a randomized controlled trial
(Peer reviewed; Journal article, 2023)Background and aims Changes in body composition may affect colorectal cancer (CRC) patient's risk of cancer recurrence, secondary cancer, and other chronic diseases. The suggested interventions for changes in body composition ... -
The Effect of Cancer Patients’ and TheirFamily Caregivers’ Physical and EmotionalSymptoms on Caregiver Burden
(Journal article; Peer reviewed, 2017)BACKGROUND: Although there is significant evidence that the family caregivers (FCs) of cancer patients can experience significant caregiver burden and symptoms, less is known about the relationships between FCs and ... -
Effect of CYP2D6 genotype on duloxetine serum concentration
(Peer reviewed; Journal article, 2023)Duloxetine is metabolized by cytochrome P450 (CYP)1A2 and CYP2D6. The aim of this study was to investigate the effect of the CYP2D6 genotype on duloxetine serum concentration adjusting for age and sex. Patients were included ... -
Effect of exercise interventions in the early phase to improve physical function after hip fracture – A systematic review and meta-analysis
(Physiotherapy;Volume 108, Journal article; Peer reviewed, 2020-05-19)Background The efficacy of exercise interventions in the early recovery phase, i.e. started within the first three months after hip fracture, has been poorly studied compared to prolonged exercise interventions. Objective ... -
The effect of new formulas for lean body mass on lean- body-mass-normalized SUV in oncologic 18F-FDG PET/CT
(Journal of Nuclear Medicine Technology;Vol. 46, No. 3, Journal article; Peer reviewed, 2018-03-28)Due to better precision and intercompatibility, the use of lean body mass (LBM) as mass estimate in the calculation of standardized uptake values (SUV) has become more common in research and clinical studies today. Thus, ... -
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6-catalyzed metabolism of solanidine
(Peer reviewed; Journal article, 2024)Cytochrome P450 2D6 (CYP2D6) is important for metabolism of 20%–25% of all clinically used drugs. Many known genetic variants contribute to the large interindividual variability in CYP2D6 metabolism, but much is still ... -
The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells
(Scientific Reports;11, Article number: 24219 (2021), Peer reviewed; Journal article, 2021-12-20)Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of ...