Browsing AHUS - Medisinsk divisjon by Issue Date

Now showing items 21-40 of 46

    • Bone turnover markers are associated with bone density, but not with fracture in end stage kidney disease: a cross-sectional study 

      Jørgensen, Hanne Skou; Winther, Simon; Bøttcher, Morten; Hauge, Ellen Margrethe; Rejnmark, Lars; Svensson, My Hanna Sofie; Ivarsen, Per (BMC Nephrology;18(1), Journal article; Peer reviewed, 2017-09-06)
      Background Fracture risk is increased in chronic kidney disease (CKD), but assessment of bone fragility remains controversial in these patients. This study investigated the associations between bone turnover markers, bone ...

    • An update on cladribine for relapsing-remitting multiple sclerosis 

      Holmøy, Trygve; Torkildsen, Øivind Fredvik; Myhr, Kjell-Morten (Expert Opinion on Pharmacotherapy;18(15), Journal article; Peer reviewed, 2017-09-11)
      INTRODUCTION: Despite recent progress, currently available therapies for relapsing remitting multiple sclerosis (MS) are only partly effective, and their use is limited by tolerability and safety issues, as well as high ...

    • Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification 

      Rutkovskiy, Arkady; Malashicheva, Anna; Sullivan, Gareth; Bogdanova, Mariia; Kostareva, Anna; Stensløkken, Kåre-Olav; Fiane, Arnt E; Vaage, Ingvar Jarle (Journal of The American Heart Association;6(9), Journal article; Peer reviewed, 2017-09-22)
      Aortic valve stenosis due to calcification of the valve leaflets is the most common valve disease in the developed world. It is the third leading cause of cardiovascular disease.1 Risk factors include male gender, smoking, ...

    • NAD+ in aging: molecular mechanisms and translational implications 

      Fang, Evandro Fei; Lautrup, Sofie; Hou, Yujun; Demarest, Tyler G; Croteau, Deborah L; Mattson, Mark P; Bohr, Vilhelm A (Trends in Molecular Medicine;23/10, Journal article; Peer reviewed, 2017-10)
      AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of ...

    • Clues for early detection of autoimmune Addison's disease - myths and realities 

      Sævik, Åse Bjorvatn; Akerman, A.-K.; Grønning, Kaja; Nermoen, Ingrid; Valland, Susanna Fonneland; Finnes, Trine Elisabeth; Isaksson, M; Dahlqvist, P; Bergthorsdottir, R; Ekwall, O; Skov, J; Nedrebø, Bjørn Gunnar; Hulting, A.-L.; Wahlberg, J; Svartberg, Johan; Höybye, C; Bleskestad, Inger Hjørdis; Jørgensen, Anders Palmstrøm; Kämpe, Olle; Øksnes, Marianne; Bensing, S; Husebye, Eystein Sverre (Journal of Internal Medicine;283(2), Journal article; Peer reviewed, 2017-11-03)
      BACKGROUND: Early detection of autoimmune Addison's disease (AAD) is important as delay in diagnosis may result in a life-threatening adrenal crisis and death. The classical clinical picture of untreated AAD is well-described, ...

    • Finasteride treatment and male breast cancer: a register-based cohort study in four Nordic countries 

      Meijer, Mathias; Thygesen, Lau Caspar; Green, Anders; Emneus, Martha; Brasso, Klaus; Iversen, Peter; Pukkalo, Eero; Bolin, Kristian; Stavem, Knut; Ersbøll, Annette Kjær (Cancer medicine;7(1), Journal article; Peer reviewed, 2017-12-13)
      A potential link has been suggested between dispensed finasteride and increased risk of male breast cancer (MBC). Due to the rare occurrence of MBC, it remains to be established if such a relationship exists. The purpose ...

    • Policy responses to hepatitis C in the Nordic countries: Gaps and discrepant reporting in the Hep-Nordic study 

      Safreed-Harmon, Kelly; Hetherington, Kristina L.; Aleman, Soo; Alho, Hannu; Dalgard, Olav; Frisch, Tove; Gottfredsson, Magnus; Weis, Nina; Lazarus, Jeffrey V. (PloS ONE;13(1), Journal article; Peer reviewed, 2018-01-30)
      Background and aims In the Nordic countries (Denmark, Finland, Iceland, Norway, Sweden), the prevalence of chronic hepatitis C virus (HCV) infection is relatively low in the general population, but is much higher among ...

    • Patient knowledge on stroke risk factors, symptoms and treatment options 

      Faiz, Kashif Waqar; Sundseth, Antje; Thommessen, Bente; Rønning, Ole M. (Vascular health and risk management;14, Journal article; Peer reviewed, 2018-02-07)
      Background: Public campaigns focus primarily on stroke symptom and risk factor knowledge, but patients who correctly recognize stroke symptoms do not necessarily know the reason for urgent hospitalization. The aim of this ...

    • Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial 

      Grebely, Jason; Dalgard, Olav; Conway, Brian; Cunningham, Evan B.; Bruggmann, Philip; Hajarizadeh, Behzad; Amin, Janaki; Bruneau, Julie; Hellard, Margaret; Litwin, Alain H.; Marks, Phillippa; Quiene, Sophie; Siriragavan, Sharmila; Applegate, Tanya L.; Swan, Tracy; Byrne, Jude; Lacalamita, Melanie; Dunlop, Adrian; Matthews, Gail V.; Powis, Jeff; Shaw, David; Thurnheer, Maria Christine; Weltmann, Martin; Kronborg, Ian; Cooper, Curtis; Feld, Jordan J.; Fraser, Chris; Dillon, John F.; Read, Phillip; Gane, Edward; Dore, Gregory J. (The lancet Gastroenterology & hepatology;3(3), Journal article; Peer reviewed, 2018-03)
      Background Despite revised guidelines that no longer exclude people who inject drugs (PWID) from treatment for hepatitis C virus (HCV) infection, many clinicians are reluctant to treat recent PWID. This study aimed to ...

    • Vertebral Bone Mineral Density Measured by Quantitative Computed Tomography With and Without a Calibration Phantom: A Comparison Between 2 Different Software Solutions 

      Therkildsen, Josephine; Thygesen, Jesper; Winther, Simon; Svensson, My Hanna Sofie; Hauge, Ellen-Margrethe; Bøttcher, Morten; Ivarsen, Per; Jørgensen, Hanne Skou (Journal of Clinical Densitometry;21(3), Journal article; Peer reviewed, 2018-03-27)
      Quantitative computed tomography (CT) can be used to quantify bone mineral density (BMD) in the spine from clinical CT scans. We aimed to determine agreement and precision of BMD measurements by 2 different methods: ...

    • Health status in subjects with suspected obstructive sleep apnea and comparison with a general population 

      Beiske, Kornelia Katalin; Stavem, Knut (Scientific reports;8(1), Journal article; Peer reviewed, 2018-04-03)
      The purpose of this study was to assess health status (HS) in patients with clinical suspicion of obstructive sleep apnea (OSA) in order to estimate the dose response relationship between HS and OSA severity, and to ...

    • Tested and reported executive problems in children and youth epilepsy 

      Hessen, Erik; Alfstad, Kristin Åshild; Torgersen, Halvor S.; Lossius, Morten (Brain and Behavior;8(5), Journal article; Peer reviewed, 2018-04-16)
      Objectives Executive problems in children and youth with epilepsy influence their ability to handle important aspects of daily life activities. The present study sought to explore factors associated with executive problems ...

    • Adherence to subcutaneous interferon beta-1a treatment using an electronic injection device: a prospective open-label scandinavian noninterventional study (The scansmart study) 

      Pedersen, Elena Didenko; Stenager, Egon; Vadgaard, J. L.; Jensen, Michael Broksgaard; Schmid, Roman; Meland, Nils; Magnussen, Gry Irene; Frederiksen, Jette Lautrup (Patient preference and adherence;12, Journal article; Peer reviewed, 2018-04-19)
      Background: Disease modifying drugs help control the course of relapsing remitting multiple sclerosis (RRMS); however, good adherence is needed for long-term outcomes. Objective: To evaluate patient adherence to treatment ...

    • Bioavailable Testosterone Is Positively Associated With Bone Mineral Density in Male Kidney Transplantation Candidates 

      Jørgensen, Hanne Skou; Winther, Simon; Bøttcher, Morten; Hauge, Ellen-Margrethe; Rejnmark, Lars; Svensson, My Hanna Sofie; Ivarsen, Per (Kidney international reports;3(3), Journal article; Peer reviewed, 2018-05)
      Introduction Low levels of sex hormones are common in patients with chronic kidney disease (CKD) and may be a contributing factor to bone fragility. We investigated associations between levels of sex hormones and bone ...

    • Prevalence of carotid plaque in a 63- to 65-Year-Old Norwegian cohort from the general population: The ACE (Akershus Cardiac Examination) 1950 study 

      Ihle-Hansen, Håkon; Vigen, Thea; Ihle-Hansen, Hege; Rønning, Ole M.; Berge, Trygve; Thommessen, Bente; Lyngbakken, Magnus; Orstad, Eivind Bjørkan; Enger, Steve; Nygård, Ståle; Røsjø, Helge; Tveit, Arnljot (Journal of the American Heart Association;7(10), Journal article; Peer reviewed, 2018-05-08)
      Background New data on extracranial carotid atherosclerosis are needed, as improved ultrasound techniques may detect more atherosclerosis, the definition of plaque has changed over the years, and better cardiovascular ...

    • Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: A case series 

      Schultz, Nina Haagenrud; Lundblad, Runar; Holme, Pål Andre (Journal of Medical Case Reports;12(1), Journal article; Peer reviewed, 2018-05-16)
      Background The lack of an antidote against factor Xa inhibitors in case of major bleeding or need for urgent surgery is a concern to clinicians. Guidelines on managing major bleeding in patients under anticoagulation with ...

    • Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: Educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB) 

      Saenger, Amy K; Jaffe, Allan S.; Body, Richard; Collinson, Paul O.; Kavsak, Peter A.; Lam, Carolyn S. P.; Lefèvre, Guillaume; Omland, Torbjørn; Ordóñez-Llanos, Jordi; Pulkki, Kari; Apple, Fred S. (Clinical Chemistry and Laboratory Medicine (CCLM);57(5), Journal article; Peer reviewed, 2018-06-10)
      Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers ...

    • Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients 

      Frigstad, Svein Oskar; Høivik, Marte Lie; Jahnsen, Jørgen; Småstuen, Milada Cvancarova; Grimstad, Tore; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Bernklev, Tomm; Moum, Bjørn; Jelsness-Jørgensen, Lars-Petter (World journal of gastroenterology;24(29), Journal article; Peer reviewed, 2018-08-07)
      AIM To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease (IBD). METHODS IBD patients were recruited from nine hospitals in the southeastern and western regions ...

    • B-cell composition in the blood and cerebrospinal fluid of multiple sclerosis patients treated with dimethyl fumarate 

      Høglund, Rune Alexander; Polak, Justyna; Vartdal, Frode; Holmøy, Trygve; Lossius, Andreas Lunde (Multiple sclerosis and related disorders;26, Journal article; Peer reviewed, 2018-08-30)
      Background:B cells may contribute to the immunopathogenesis of multiple sclerosis (MS). Dimethyl fumarate(DMF) has recently been shown to reduce the frequency of memory B cells in blood, but it is not known whetherthe drug ...

    • Effect of exogenous estrogens and progestogens on the course of migraine during reproductive age: A consensus statement by the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESCRH) 

      Sacco, Simona; Merki-Feld, Gabriele S.; Ægidius, Karen Lehrmann; Bitzer, Johannes; Canonico, Marianne; Gantenbein, Andreas R.; Kurth, Tobias; Lampl, Christian; Lidegaard, Øjvind; MacGregor, Elizabeth Anne; van den Brink, Antoinette Maassen; Mitsikostas, Dimos-Dimitrios; Nappi, Rossella Elena; Ntaios, George; Paemeleire, Koen; Sandset, Per Morten; Terwindt, Gisela Marie; Vetvik, Kjersti; Martelletti, Paolo (The journal of headache and pain;19(1), Journal article; Peer reviewed, 2018-08-31)
      We systematically reviewed data about the effect of exogenous estrogens and progestogens on the course of migraine during reproductive age. Thereafter a consensus procedure among international experts was undertaken to ...