• Bioingeniøren som diagnostisk samarbeidspartner i helsevesenet 

      Larsen, Marianne; Almås, Synnøve Hofseth (Bioingeniøren;2018(4), Journal article; Peer reviewed, 2018-04-27)
      Bakgrunn. Målet med denne studien var å undersøke om en bioingeniør kan inngå som en diagnostisk samarbeidspartner (DSP) og derved oppleves som en naturlig del av et tverrprofesjonelt team i helsevesenet. Metode. Det ...
    • Characterization of physicochemical and colloidal properties of hydrogel chitosan-coated iron-oxide nanoparticles for cancer therapy 

      Catalano, Enrico; Benedetto, Andrea Di (Journal of Physics: Conference Series;841, Journal article; Peer reviewed, 2017-05)
      Superparamagnetic iron oxide nanoparticles have recently been investigated for their potential to kill cancer cells with promising results, owing to their ability to be targeted and heated by magnetic fields. In this study, ...
    • The copeptin response after physical activity is not associated with cardiac biomarkers or asymptomatic coronary artery disease: The North Sea Race Endurance Exercise Study (NEEDED) 2013 

      Aakre, Kristin Moberg; Kleiven, Øyunn; Skadberg, Øyvind; Bjørkavoll-Bergseth, Magnus; Melberg, Tor Harald; Strand, Heidi; Hagve, Tor-Arne; Ørn, Stein (Clinical biochemistry;52, Journal article; Peer reviewed, 2017-10-26)
      Background:Copeptin concentrations increase both during acute coronary syndrome and following physicalexercise. The relationship between copeptin increase following physical exercise and coronary artery disease(CAD) is ...
    • Design of the CAPABLE Prototype: Preliminary Results of Citizen Expectations 

      Janson, Astri Letnes; Moen, Anne; Fuglerud, Kristin Skeide (Linköping Electronic Conference Proceedings;161, Conference object; Peer reviewed, 2019-11)
      Having access to and opportunity to an overview of all personal health-related information is important to citizen health empowerment. Today, citizens can access subsets of their health information through dedicated, ...
    • Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer 

      Kruger, Kristi; Wik, Elisabeth; Knutsvik, Gøril; Nalwoga, Hawa; Klingen, Tor Audun; Arnes, Jarle; Chen, Ying; Mannelqvist, Monica; Dimitrakopoulou, Konstantina; Stefansson, Ingunn; Birkeland, Even; Aas, Turid; Tobin, Nicholas P; Jonassen, Inge; Bergh, Jonas; Foulkes, William D; Akslen, Lars A (Scientific Reports;7(1), Journal article; Peer reviewed, 2017-04-24)
      We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent ...
    • Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer 

      Aziz, Sura Mohammed; Wik, Elisabeth; Knutsvik, Gøril; Klingen, Tor Audun; Chen, Ying; Davidsen, Benedicte; Aas, Hans; Aas, Turid; Akslen, Lars A (PloS one;12(2), Journal article; Peer reviewed, 2017-02-15)
      Presence of lymph node (LN) metastasis is a strong prognostic factor in breast cancer, whereas the importance of extra-nodal extension and other nodal tumor features have not yet been fully recognized. Here, we examined ...
    • Genotypic characterization of gentamicin and cephalosporin 1 resistant Escherichia coli 2 isolates from blood cultures in a Norwegian university hospital 2011-2015 

      Fladberg, Øyvind Andreas; Jørgensen, Silje; Aamot, Hege Vangstein (Antimicrobial Resistance & Infection Control;121(6), Journal article; Peer reviewed, 2017-11-29)
      Background: Cephalosporin resistance in clinical E. coli isolates is increasing internationally. The increase has been caused by virulent and often multidrug-resistant clones, especially the extended spectrum beta-lactamase ...
    • Helseatferd blant blodgivere 

      Nybruket, Monica Jenssen; Llohn, Abid Hussain; Knutsen, Teresa Risopatron; Karlsen, Bente Anita Grande; Skogheim, Ruby; Bråten, Sissel; Qvale, Ingerid; Luong, Vinh Hoang; Hermundstad, Brita; Mousavi, Seyed Ali (Journal article; Peer reviewed, 2018-10-02)
      Formål: Formålet med denne studien var å kartlegge helseatferd (tobakks- og alkoholbruk og fysisk aktivitet) i et utvalg av blodgivere, og undersøke i hvilken grad resultatene fra studien gjenspeiler helseatferd i den ...
    • In vitro biological validation and cytocompatibility evaluation of hydrogel iron-oxide nanoparticles 

      Catalano, Enrico (AIP Conference Proceedings;1873, Journal article; Peer reviewed, 2017-08-02)
      Superparamagnetic iron oxide nanoparticles (MNPs) have recently been investigated for their excellent biocompatibility as well as multi-purpose biomedical potential with promising results, owing to their ability to be ...
    • Initial Phase NT-proBNP, but Not Copeptin and High-Sensitivity Cardiac Troponin-T Yielded Diagnostic and Prognostic Information in Addition to Clinical Assessment of Out-of-Hospital Cardiac Arrest Patients With Documented Ventricular Fibrillation 

      Aarsetøy, Reidun; Aarsetøy, Hildegunn; Hagve, Tor-Arne; Strand, Heidi; Staines, Harry; Nilsen, Dennis W. T. (Frontiers in cardiovascular medicine;5, Journal article; Peer reviewed, 2018-06-07)
      Aim: Sudden cardiac arrest (SCA) secondary to ventricular fibrillation (VF) may be due to different cardiac conditions. We investigated whether copeptin, hs-cTnT and NT-proBNP in addition to clinical assessment may help ...
    • An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study 

      Zeller, Michelle P.; Barty, Rebecca; Aandahl, Astrid; Apelseth, Torunn Oveland; Callum, Jeannie; Dunbar, Nancy M.; Elahie, Allahna; Garritsen, Henk; Hancock, Helen; Kutner, José Mauro; Manukian, Belinda; Mizuta, Shuichi; Okuda, Makoto; Pagano, Monica B.; Pogłód, Ryszard; Rushford, Kylie; Selleng, Kathleen; Sørensen, Claess Henning; Sprogøe, Ulrik; Staves, Julie; Weiland, Thorsten; Wendel, Silvano; Wood, Erica M.; Watering, Leo van de; Wordragen-Vlaswinkel, Maria van; Ziman, Alyssa; Zwaginga, Jaap Jan; Murphy, Michael F.; Heddle, Nancy M.; Yazer, Mark H. (Transfusion;57(10), Journal article; Peer reviewed, 2017-08-25)
      BACKGROUND: Transfusion of group O blood to non-O recipients, or transfusion of D- blood to D+ recipients, can result in shortages of group O or D- blood, respectively. This study investigated RBC utilization patterns at ...
    • Interval breast cancer rates and histopathologic tumor characteristics after false-positive findings at mammography in a populationbased screening program 

      Hofvind, Solveig; Sagstad, Silje; Sebuødegård, Sofie; Chen, Ying; Roman, Martha; Lee, Christoph I. (Radiology;287(1), Journal article; Peer reviewed, 2017-12-14)
      Purpose To compare rates and tumor characteristics of interval breast cancers (IBCs) detected after a negative versus false-positive screening among women participating in the Norwegian Breast Cancer Screening ...
    • Long-term follow-up of a hospital-based, multi-intervention programme in type 2 diabetes mellitus: impact on cardiovascular events and death 

      Ofstad, Anne Pernille; Ulimoen, Geir Reinvik; Orvik, Elsa; Birkeland, Kåre I; Gullestad, Lars; Fagerland, Morten; Johansen, Odd Erik (Journal of International Medical Research;45(5), Journal article; Peer reviewed, 2017-06-19)
      Objective To report the long-term impact on cardiovascular (CV) outcomes and mortality of a 2-year hospital-based multi-interventional care programme as compared with general practitioner (GP)-provided standard ...
    • No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections 

      Smeland, Tor Eirik; Müller, Fredrik; Blomfeldt, Anita; Stavem, Knut; Aamot, Hege Vangstein (Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS);125(10), Journal article; Peer reviewed, 2017-07-24)
      Staphylococcus aureus bloodstream infections (SABSI) are associated with high morbidity and mortality. The Toll‐like receptor 2 (TLR2) and Toll‐interacting protein (TOLLIP) are important in recognition and regulation of ...
    • Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics 

      Jabeen, Shakila; Espinoza, Jaime; Torland, Lilly Anne; Zucknick, Manuela; Kumar, Surendra; Haakensen, Vilde Drageset; Luders, Torben; Engebraaten, Olav; Børresen-Dale, Anne-Lise; Kyte, Jon A.; Gromov, Pavel; Naume, Bjørn; Kristensen, Vessela N.; Gromova, Irina; Tekpli, Xavier (Oncoimmunology;8(2), Journal article; Peer reviewed, 2018-06-05)
      Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the potential clinical value of infiltrating lymphocytes at the tumor ...
    • Norwegian patients and retail chicken meat share cephalosporin-resistant Escherichia coli and IncK/blaCMY-2 resistance plasmids 

      Berg, Einar Sverre; Wester, Astrid Lousie; Ahrenfeldt, J; Mo, Solveig Sølverød; Slettemeås, Jannice Schau; Steinbakk, Martin; Samuelsen, Ørjan; Grude, Nils; Simonsen, Gunnar Skov; Löhr, Iren Høyland; Jørgensen, Silje; Tofteland, Ståle; Lund, O; Dahle, Ulf R; Sunde, Marianne (Clinical microbiology and infection;23(6), Journal article; Peer reviewed, 2017-06)
      Objectives In 2012 and 2014 the Norwegian monitoring programme for antimicrobial resistance in the veterinary and food production sectors (NORM-VET) showed that 124 of a total of 406 samples (31%) of Norwegian retail ...
    • Peripheral arthritis in patients with long-term inflammatory bowel disease. Results from 20 years of follow-up in the IBSEN study 

      Ossum, Alvilde Maria; Palm, Øyvind; Småstuen, Milada Cvancarova; Solberg, Inger Camilla; Vatn, Morten H; Moum, Bjørn; Høivik, Marte Lie (Scandinavian Journal of Gastroenterology;53(10-11), Journal article; Peer reviewed, 2018-10-24)
      Objectives: Peripheral arthritis and related musculoskeletal manifestations, often classified as peripheral spondyloarthritis, are frequently seen in patients with inflammatory bowel disease (IBD). Few long-term studies ...
    • Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab 

      Jabeen, Shakila; Zucknick, Karola Manuela; Nome, Marianne Eikhom; Dannenfelser, Ruth; Fleischer, Thomas; Kumar, Surendra; Luders, Torben; Gythfeldt, Hedda; Troyanskya, Olga; Kyte, Jon A.; Børresen-Dale, Anne-Lise; Naume, Bjørn; Tekpli, Xavier; Engebråten, Olav; Kristensen, Vessela N. (Oncoimmunology;7(11), Journal article; Peer reviewed, 2018-01-08)
      A high concentration of circulating vascular endothelial growth factor (VEGF) in cancer patients is associated with an aggressive tumor phenotype. Here, serum levels of 27 cytokines and blood cell counts were assessed in ...
    • Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer 

      Bemanian, Vahid; Noone, John Cristopher; Sauer, Torill; Touma, Joel Joul; Vetvik, Katja K.; Söderberg-Naucler, Cecilia; Lindstrøm, Jonas Christoffer; Bukholm, Ida Rashida Khan; Kristensen, Vessela N.; Geisler, Jürgen (Breast cancer research and treatment;172(2), Journal article; Peer reviewed, 2018-08-21)
      Purpose We have compared the mutational profiles of human breast cancer tumor samples belonging to all major subgroups with special emphasis on triple-negative breast cancer (TNBC). Our major goal was to identify specific ...
    • A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America 

      Rossi, Benedito Mauro; Palmero, Edenir Inêz; López-Kostner, Francisco; Sarroca, Carlos; Vaccaro, Carlos Alberto; Spirandelli, Florencia; Ashton-Prolla, Patricia; Rodriguez, Yenni; Galvão, Henrique de Campos Reis; Reis, Rui Manuel; dePaula, André Escremim; Romagnolo, Luis Gustavo Capochin; Alvarez, Karin; Valle, Adriana Della; Neffa, Florencia; Kalfayan, Pablo German; Spirandelli, Enrique; Chialina, Sergio; Angulo, Melva Gutiérrez; Castro-Mujica, Maria del Carmen; de Monte, Julio Sanchez; Quispe, Richard; de Silva, Sabrina Daniela; Rossi, Norma Teresa; Barletta-Carrillo, Claudia; Revollo, Susann; Taborga, Ximena; Morillas, L. Lena; Tubeuf, Hélène; Monteiro-Santos, Erika Maria; Piñero, Tamara Alejandra; Dominguez-Barrera, Constantino; Wernhoff, Patrik; Martins, Alexandra; Hovig, Eivind; Møller, Pål; Valentin, Mev Dominguez (BMC cancer;17(1), Journal article; Peer reviewed, 2017-09-05)
      Background Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants ...