• Maternal human chorionic gonadotrophin concentrations in very early pregnancy and risk of hyperemesis gravidarum: A retrospective cohort study of 4372 pregnancies after in vitro fertilization 

      Dypvik, Johanne; Lid, Andrea Johanne; Tanbo, Tom Gunnar; Eskild, Anne (European Journal of Obstetrics, Gynecology, and Reproductive Biology;221, Journal article; Peer reviewed, 2018-02)
      Objective We investigated the association of human chorionic gonadotrophin (hCG) concentrations on a fixed day in very early pregnancy with development of hyperemesis gravidarum. Study design This retrospective cohort ...
    • Måleegenskaper ved den norske versjonen av Children’s Global Assessment Scale (CGAS) 

      Jozefiak, Thomas; Hanssen-Bauer, Ketil; Bjelland, Ingvar (PsykTestBarn;1(3), Journal article; Peer reviewed, 2018-10-23)
      Children’s Global Assessment Scale (CGAS) ble laget av David Shaffer og medarbeidere i 1983. Den skåres av kliniker og er et mål på barns psykososiale funksjonsnivå i den siste måneden før vurderingstidspunktet på en skala ...
    • Morbidity outcomes after surgical aortic valve replacement 

      Auensen, Andreas; Hussain, Amjad Iqbal; Bendz, Bjørn; Aaberge, Lars; Falk, Ragnhild Sørum; Hansen, Marte; Bye, Eva; Andreassen, Johanna; Beitnes, Jan Otto; Rein, Kjell Arne; Pettersen, Kjell I; Gullestad, Lars (Open Heart;4(1), Journal article; Peer reviewed, 2017-04-13)
      Objective In patients with mild to moderate operative risk, surgical aortic valve replacement (SAVR) is still the preferred treatment for patients with severe symptomatic aortic stenosis (AS). Aiming to broaden the knowledge ...
    • NAD+ in aging: molecular mechanisms and translational implications 

      Fang, Evandro Fei; Lautrup, Sofie; Hou, Yujun; Demarest, Tyler G; Croteau, Deborah L; Mattson, Mark P; Bohr, Vilhelm A (Trends in Molecular Medicine;23/10, Journal article; Peer reviewed, 2017-10)
      AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of ...
    • A national, prospective observational study of first recurrence after primary treatment for gynecological cancer in Norway 

      Vistad, Ingvild; Bjørge, Line; Popova, Olesya; Fiane, Bent; Sachse, Kurt; Tjugum, Ivar Jostein; Skrøppa, Siri; Bentzen, Anne Gry; Stokstad, Trine; Iversen, Grete Alræk; Salvesen, Helga Birgitte; Kristensen, Gunnar S Balle; Dørum, Anne (Acta Obstetricia et Gynecologica Scandinavica;96(10), Journal article; Peer reviewed, 2017-08-10)
      INTRODUCTION: Gynecological cancer patients are routinely followed up for five years after primary treatment. However, the value of such follow up has been debated, as retrospective studies indicate that first recurrence ...
    • No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections 

      Smeland, Tor Eirik; Müller, Fredrik; Blomfeldt, Anita; Stavem, Knut; Aamot, Hege Vangstein (Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS);125(10), Journal article; Peer reviewed, 2017-07-24)
      Staphylococcus aureus bloodstream infections (SABSI) are associated with high morbidity and mortality. The Toll‐like receptor 2 (TLR2) and Toll‐interacting protein (TOLLIP) are important in recognition and regulation of ...
    • Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics 

      Jabeen, Shakila; Espinoza, Jaime; Torland, Lilly Anne; Zucknick, Manuela; Kumar, Surendra; Haakensen, Vilde Drageset; Luders, Torben; Engebraaten, Olav; Børresen-Dale, Anne-Lise; Kyte, Jon A.; Gromov, Pavel; Naume, Bjørn; Kristensen, Vessela N.; Gromova, Irina; Tekpli, Xavier (Oncoimmunology;8(2), Journal article; Peer reviewed, 2018-06-05)
      Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the potential clinical value of infiltrating lymphocytes at the tumor ...
    • A Norwegian 15D value algorithm: proposing a new procedure to estimate 15D value algorithms 

      Michel, Yvonne Anne; Augestad, Liv Ariane; Barra, Georg Mathias Honore; Rand, Kim (Quality of Life Research;28(5), Journal article; Peer reviewed, 2018-11-30)
      Purpose So far there is no Norwegian value algorithm to inform healthcare decision making. The 15D health state values estimated with the original 15D valuation procedure tend to be higher than the values of other generic ...
    • Norwegian patients and retail chicken meat share cephalosporin-resistant Escherichia coli and IncK/blaCMY-2 resistance plasmids 

      Berg, Einar Sverre; Wester, Astrid Lousie; Ahrenfeldt, J; Mo, Solveig Sølverød; Slettemeås, Jannice Schau; Steinbakk, Martin; Samuelsen, Ørjan; Grude, Nils; Simonsen, Gunnar Skov; Löhr, Iren Høyland; Jørgensen, Silje; Tofteland, Ståle; Lund, O; Dahle, Ulf R; Sunde, Marianne (Clinical microbiology and infection;23(6), Journal article; Peer reviewed, 2017-06)
      Objectives In 2012 and 2014 the Norwegian monitoring programme for antimicrobial resistance in the veterinary and food production sectors (NORM-VET) showed that 124 of a total of 406 samples (31%) of Norwegian retail ...
    • Novel biomarkers of cardiovascular disease: Applications in clinical practice 

      Lyngbakken, Magnus; Myhre, Peder Langeland; Røsjø, Helge; Omland, Torbjørn (Critical reviews in clinical laboratory sciences;56(1), Journal article; Peer reviewed, 2018-11-20)
      Measurement of biomarkers has revolutionized the work-up of patients with suspected cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are the natriuretic peptides in the diagnosis and ...
    • Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis 

      Vesterhus, Mette; Holm, Anders; Hov, Johannes Espolin Roksund; Nygård, Ståle; Schrumpf, Erik; Melum, Espen; Thorbjørnsen, Liv Wenche; Paulsen, Vemund; Lundin, Knut Erik Aslaksen; Dale, Inge; Gilja, Odd Helge; Zweers, Serge J.; Vatn, Morten H.; Schaap, Frank G.; Jansen, Peter L. M.; Ueland, Thor; Røsjø, Helge; Moum, Bjørn; Ponsioen, Cyriel Y.; Boberg, Kirsten Muri; Färkkilä, Martti; Karlsen, Tom Hemming; Lund-Johansen, Fridtjof (Journal of hepatology;66(6), Journal article; Peer reviewed, 2017-02-02)
      Background & Aims Prognostic biomarkers are lacking in primary sclerosing cholangitis, hampering patient care and the development of therapy. We aimed to identify novel protein biomarkers of disease severity and prognosis ...
    • Obesity and osteoarthritis in knee, hip and/or hand: An epidemiological study in the general population with 10 years follow-up 

      Grotle, Margreth; Hage, Kåre Birger; Natvig, Bård; Dahl, Fredrik Andreas; Kvien, Tore Kristian (BMC Musculoskeletal Disorders;9(1), Journal article; Peer reviewed, 2008-10-02)
      Background: Obesity is one of the most important risk factors for osteoarthritis (OA) in knee(s). However, the relationship between obesity and OA in hand(s) and hip(s) remains controversial and needs further investigation. ...
    • "Open Dialogue behind locked doors" - exploring the experiences of patients ,family members, and professionals With network meeetings in a locked psychiatric hospital unit: A qualitative study 

      Ritva, Jacobsen; Sørgård, Jorunn; Karlsson, Bengt Eirik; Seikkula, Jaakko; Kim, Hesook Suzie (Scandinavian Psychologist;5, Journal article; Peer reviewed, 2018-08-10)
      This paper explores and describes the experiences of patients, family members, and professionals with the Open Dialogue approach to network meetings at a locked psychiatric hospital unit in Norway. Previous research on ...
    • Optimal chest compression rate and compression to ventilation ratio in delivery room resuscitation: Evidence from newborn piglets and neonatal manikins 

      Solevåg, Anne Lee; Schmölzer, Georg M (Frontiers in Pediatrics;5, Journal article; Peer reviewed, 2017-01-23)
      Cardiopulmonary resuscitation (CPR) duration until return of spontaneous circulation (ROSC) influences survival and neurologic outcomes after delivery room (DR) CPR. High quality chest compressions (CC) improve cerebral ...
    • Optimal conventional mechanical ventilation in full-term newborns: A systematic review 

      Solberg, Marianne Trygg; Solevåg, Anne Lee; Clarke, Sara (Advances in Neonatal Care;18(6), Journal article; Peer reviewed, 2018-12)
      Background: Most studies examining the best mechanical ventilation strategies in newborn infants have been performed in premature infants with respiratory distress syndrome. Purpose: To identify and synthesize the ...
    • Optimizing home hospital health service delivery in norway using a combined geographical information system, agent based, discrete event simulation model 

      Viana, Joe; Ziener, Vigids Margrethe; Ponton, Irene Gynnild; Holhjem, Marita Sommer; Thørgersen, Lisa Johanne; Simonsen, Tone Breines (Proceedings of the 2017 Winter Simulation Conference;pp. 128, Conference object, 2018-01-08)
      Home hospital services; provide some hospital level services at the patient's residence. The services include for example: palliative care, administering chemotherapy drugs, changing dressings and care for newborns. The ...
    • Overall Survival in Renal Cell Carcinoma after Introduction of Targeted Therapies: A Norwegian Population-Based Study 

      Beisland, Christian; Johannesen, Tom Bjørge; Klepp, Olbjørn; Axcrona, Ulrika; Torgersen, Knut Martin; Kowalski, Jan; Solli, Oddvar; Sandin, Rickard; Oldenburg, Jan (OncoTargets and therapy;10, Journal article; Peer reviewed, 2017-01-16)
      Background: This population-wide retrospective, non-interventional registry study assessed changes in overall survival (OS) and factors influencing OS in Norwegian patients with renal cell carcinoma (RCC). Methods: Two ...
    • Pantoprazole in patients at risk for gastrointestinal bleeding in the ICU 

      Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt; Schefold, Jörg Christian; Keus, Frederik; Guttormsen, Anne Berit; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Rasmussen, Bodil S.; Siegemund, Martin; Bundegaard, Helle; Elkmann, Thomas; Jensen, Jacob V.; Nielsen, Rune D.; Liboriussen, Lisbeth; Bestle, Morten Heiberg; Elkjær, Jeanie M.; Palmqvist, Dorte F.; Bäcklund, Minna; Laake, Jon Henrik; Bådstøløkken, Per Martin; Grönlund, Juha; Breum, Olena; Walli, Akil; Winding, Robert; Iversen, Susanne; Jarnvig, Inger-Lise; White, Jonathan O.; Brand, Björn; Madsen, Martin Bruun; Quist, Lars; Thornberg, Klaus J.; Møller, Anders; Wiis, Jørgen; Granholm, Anders; Anthon, Carl Thomas; Meyhoff, Tine Sylvest; Hjortrup, Peter B.; Aagard, Søren R.; Andreassen, Jo B.; Sørensen, Christina Ankjær; Haure, Pernille; Hauge, Jacob; Hollinger, Alexa; Scheuzger, Jonas; Tuchscherer, Daniel; Vuilliomenet, Thierry; Takala, Jukka; Jacob, Stephan M.; Vang, Marianne L.; Pælestik, Kim B.; Andersen, Karen L. D.; van der Horst, Ivan C. C.; Dieperink, Willem; Fjølner, Jesper; Kjer, Cilia Klara Winther; Sølling, Christoffer G.; Karttunen, Johanna; Morgan, Matt P. G.; Sjøbø, Brit Ågot; Engstrøm, Janus; Agerholm-Larsen, Birgit; Møller, Morten H. (New England Journal of Medicine;379(23), Journal article; Peer reviewed, 2018-12-06)
      BACKGROUND Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. METHODS In this European, multicenter, parallel-group, ...
    • Paracrine Activity from Adipose-Derived Stem Cells on in Vitro Wound Healing in Human Tympanic Membrane Keratinocytes 

      Ong, Huan Ting; Redmond, Sharon L.; Marano, Robert J.; Atlas, Marcus D.; Unge, Magnus Von; Aabel, Peder; Dilley, Rodney J. (Stem Cells and Development ISSN 1547-3287 e-ISSN 1557-8534 NVI-nivå 1;26(6), Journal article; Peer reviewed, 2017)
      Stem cell therapies for tympanic membrane repair have shown initial experimental success using mesenchymal stem cells in rat models to promote healing; however, the mechanisms providing this benefit are not known. We ...
    • Patient knowledge on stroke risk factors, symptoms and treatment options 

      Faiz, Kashif Waqar; Sundseth, Antje; Thommessen, Bente; Rønning, Ole M. (Vascular health and risk management;14, Journal article; Peer reviewed, 2018-02-07)
      Background: Public campaigns focus primarily on stroke symptom and risk factor knowledge, but patients who correctly recognize stroke symptoms do not necessarily know the reason for urgent hospitalization. The aim of this ...