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dc.contributor.authorJenum, Anne Karen
dc.contributor.authorMørkrid, Kjersti
dc.contributor.authorSletner, Line
dc.contributor.authorVangen, Siri
dc.contributor.authorTorper, Johan
dc.contributor.authorNakstad, Britt
dc.contributor.authorVoldner, Nanna
dc.contributor.authorRognerud-jensen, Odd H,
dc.contributor.authorStølevik, Sveinung Berntsen
dc.contributor.authorMosdøl, Annhild
dc.contributor.authorSkrivarhaug, Torild
dc.contributor.authorVårdal, Mari H.
dc.contributor.authorHolme, Ingar Morten K.
dc.contributor.authorYajnik, Chittaranjan S.
dc.contributor.authorBirkeland, Kåre I.
dc.date.accessioned2012-02-08T12:17:16Z
dc.date.available2012-02-08T12:17:16Z
dc.date.issued2011
dc.identifier.citationJenum, A.K., Mørkrid, K., Sletner, L., Vangen, S., Torper, J., Nakstad, B., Birkeland, K. (2011). Gestational diabetes with the WHO and modified International Association of Diabetes and Pregnancy Study Groups criteria: Impact of ethnicity. A population-based cohort study. European Journal of Endocrinology,en_US
dc.identifier.issn0804-4643
dc.identifier.otherFRIDAID 863843
dc.identifier.urihttps://hdl.handle.net/10642/1119
dc.description.abstractObjective The International Association of Diabetes and Pregnancy Study Groups (IADPSG) recently proposed new criteria for diagnosing gestational diabetes mellitus (GDM). We compared prevalence rates, risk factors, and the effect of ethnicity using the World Health Organization (WHO) and modified IADPSG criteria. Methods This was a population-based cohort study of 823 (74% of eligible) healthy pregnant women, of whom 59% were from ethnic minorities. Universal screening was performed at 28±2 weeks of gestation with the 75 g oral glucose tolerance test (OGTT). Venous plasma glucose (PG) was measured on site. GDM was diagnosed as per the definition of WHO criteria as fasting PG (FPG) ≥7.0 or 2-h PG ≥7.8 mmol/l; and as per the modified IADPSG criteria as FPG ≥5.1 or 2-h PG ≥8.5 mmol/l. Results OGTT was performed in 759 women. Crude GDM prevalence was 13.0% with WHO (Western Europeans 11%, ethnic minorities 15%, P=0.14) and 31.5% with modified IADPSG criteria (Western Europeans 24%, ethnic minorities 37%, P< 0.001). Using the WHO criteria, ethnic minority origin was an independent predictor (South Asians, odds ratio (OR) 2.24 (95% confidence interval (CI) 1.26–3.97); Middle Easterners, OR 2.13 (1.12–4.08)) after adjustments for age, parity, and prepregnant body mass index (BMI). This increased OR was unapparent after further adjustments for body height (proxy for early life socioeconomic status), education and family history of diabetes. Using the modified IADPSG criteria, prepregnant BMI (1.09 (1.05–1.13)) and ethnic minority origin (South Asians, 2.54 (1.56–4.13)) were independent predictors, while education, body height and family history had little impact. Conclusion GDM prevalence was overall 2.4-times higher with the modified IADPSG criteria compared with the WHO criteria. The new criteria identified many subjects with a relatively mild increase in FPG, strongly associated with South Asian origin and prepregnant overweighten_US
dc.language.isoengen_US
dc.publisherEuropean Society of Endocrinologyen_US
dc.relation.ispartofseriesEuropean Journal of Endocrinology;2011
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Gynekologi og obstetrikk: 756en_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Endokrinologi: 774en_US
dc.subjectDiabetesen_US
dc.subjectEtnisiteten_US
dc.subjectSvangerskapen_US
dc.titleImpact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a population-based cohort studyen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.version© 2012 European Society of Endocrinology This is an Open Access article distributed under the terms of the European Journal of Endocrinology's Re-use Licence which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.identifier.doihttp://dx.doi.org/10.1530/EJE-11-0866


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