• Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19 

      Aamodt, Anne Hege; Høgestøl, Einar August; Popperud, Trine Haug; Holter, Jan Cato; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Stiksrud, Birgitte; Paulsen, Else Quist; Berge, Tone; Barratt-Due, Andreas; Aukrust, Pål; Heggelund, Lars; Blennow, Kaj; Zetterberg, Henrik; Harbo, Hanne Flinstad (Journal of Neurology;, Peer reviewed; Journal article, 2021-03-20)
      Objective To test the hypotheses that blood biomarkers for nervous system injury, serum concentrations of neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAp) can serve as biomarkers for disease ...
    • Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis 

      Brune-Ingebretsen, Synne; Høgestøl, Einar August; de Rosbo, Nicole Kerlero; Berg-Hansen, Pål; Brunborg, Cathrine; Blennow, Kaj; Zetterberg, Henrik; Paul, Friedemann; Uccelli, Antonio; Villoslada, Pablo; Harbo, Hanne-Cathrin Flinstad; Berge, Tone (Peer reviewed; Journal article, 2023)
      Changes is lymphocyte subpopulations in peripheral blood have been proposed as biomarkers for evaluation of disease activity in multiple sclerosis (MS). Serum neurofilament light chain (sNfL) is a biomarker reflecting ...
    • Impaired synaptic function is linked to cognition in Parkinson's disease 

      Selnes, Per; Stav, Ane Løvli; Johansen, Krisztina Kunszt; Bjørnerud, Atle; Coello, Sebastien Christopher; Auning, Eirik; Kalheim, Lisa Flem; Almdahl, Ina Selseth; Hessen, Erik; Zetterberg, Henrik; Blennow, Kaj; Årsland, Dag; Fladby, Tormod (Annals of Clinical and Translational Neurology;4(10), Journal article; Peer reviewed, 2017-08-31)
      Objective Cognitive impairment is frequent in Parkinson's disease, but the underlying mechanisms are insufficiently understood. Because cortical metabolism is reduced in Parkinson's disease and closely associated with ...
    • Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders 

      Eide, Per Kristian; Lashkarivand, Aslan; Pripp, Are Hugo; Valnes, Lars Magnus; Hovd, Markus Herberg; Ringstad, Geir; Blennow, Kaj; Zetterberg, Henrik (Peer reviewed; Journal article, 2023)
      Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently emerged to be crucial, and plasma biomarkers of neurodegen- eration were newly introduced to predict neurological disease. This ...