Blar i ODA Open Digital Archive på forfatter "Woldemariam, Nardos Tesfaye"
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Characterization of miRNAs in cultured atlantic salmon head kidney monocyte-like and macrophage-like cells
Smith, Nicole; Woldemariam, Nardos Tesfaye; Rise, Matthew L.; Andreassen, Rune (International Journal of Molecular Sciences;Volume 21 / Issue 11, Journal article; Peer reviewed, 2020-06-02)Macrophages are among the first cells to respond to infection and disease. While microRNAs (miRNAs) are involved in the process of monocyte-to-macrophage differentiation in mammals, less is known in teleost fish. Here, ... -
Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
Chakraborty, Setu; Woldemariam, Nardos Tesfaye; Visnovska, Tina; Rise, Matthew L.; Santander, Javier; Andreassen, Rune (Biology;Volume 11 / Issue 1, Peer reviewed; Journal article, 2022-01-13)MicroRNAs (miRNAs) are endogenous small RNA molecules involved in the post-transcriptional regulation of protein expression by binding to the mRNA of target genes. They are key regulators in teleost development, maintenance ... -
Dietary Immunostimulant CpG Modulates MicroRNA Biomarkers Associated with Immune Responses in Atlantic Salmon (Salmo salar)
Xue, Xi; Woldemariam, Nardos Tesfaye; Rise, Matthew L.; Andreassen, Rune (Cells;Volume 8, Issue 12, Journal article; Peer reviewed, 2019-12-05)MicroRNAs (miRNAs) are key regulators in fish immune responses. However, no study has previously characterized the impact of polyriboinosinic polyribocytidylic acid (pIC) and formalin-killed typical Aeromonas salmonicida ... -
Expanding the miRNA Repertoire in Atlantic Salmon; Discovery of IsomiRs and miRNAs Highly Expressed in Different Tissues and Developmental Stages
Woldemariam, Nardos Tesfaye; Høyheim, Bjørn; Andreassen, Rune (Cells;Volume 8, Issue 1, Journal article; Peer reviewed, 2019-01-11)MicroRNAs (miRNAs) are important post-transcriptional gene expression regulators. Here, 448 different miRNA genes, including 17 novel miRNAs, encoding for 589 mature Atlantic salmon miRNAs were identified after sequencing ... -
miRNAs Predicted to Regulate Host Anti-viral Gene Pathways in IPNV-Challenged Atlantic Salmon Fry Are Affected by Viral Load, and Associated With the Major IPN Resistance QTL Genotypes in Late Infection
Woldemariam, Nardos Tesfaye; Agafonov, Aleksander; Sindre, Hilde; Høyheim, Bjørn; Andreassen, Rune (Frontiers in Immunology;September 2020 | Volume 11 | Article 2113, Journal article; Peer reviewed, 2020-09-11)Infectious pancreatic necrosis virus (IPNV) infection has been a major problem in salmonid aquaculture. Marker-assisted selection of individuals with resistant genotype at the major IPN quantitative trait locus (IPN-QTL) ... -
Modulation of hepatic miRNA expression in Atlantic salmon (Salmo salar) by family background and dietary fatty acid composition
Østbye, Tone-Kari K; Woldemariam, Nardos Tesfaye; Lundberg, Camilla S.; Berge, Gerd Marit; Ruyter, Bente; Andreassen, Rune (Journal of Fish Biology;, Journal article; Peer reviewed, 2020-12-17)This study finds significant differences in hepatic fatty acid composition between four groups of Atlantic salmon (Salmo salar) consisting of offspring from families selected for high and low capacities to express the delta ... -
Transcriptome Profiling of Atlantic Salmon Adherent Head Kidney Leukocytes Reveals That Macrophages Are Selectively Enriched During Culture
Smith, Nicole; Umasuthan, Navaneethaiyer; Kumar, Surendra; Woldemariam, Nardos Tesfaye; Andreassen, Rune; Christian, Sherri; Rise, Matthew L. (Frontiers in Immunology;August 2021 | Volume 12 | Article 709910, Peer reviewed; Journal article, 2021-08-16)The Atlantic salmon (Salmo salar) is an economically important fish, both in aquaculture and in the wild. In vertebrates, macrophages are some of the first cell types to respond to pathogen infection and disease. While ...