Blar i ODA Open Digital Archive på forfatter "Stokke, Caroline"
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Amyloid-β PET—Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic
Müller, Ebba Gløersen; Edwin, Trine Holt; Stokke, Caroline; Navelsaker, Sigrid Stensby; Babovic, Almira; Bogdanovic, Nenad; Knapskog, Anne Brita; Revheim, Mona-Elisabeth (PLoS ONE;14(8): e0221365, Journal article; Peer reviewed, 2019-08-05)Background: Alzheimer’s disease (AD) remains a clinical diagnosis but biomarkers from cerebrospinal fluid (CSF) and more lately amyloid imaging with positron emission tomography (PET), are important to support a diagnosis ... -
Biodistribution and dosimetry results from a phase 1 trial of therapy with the antibody-Radionuclide conjugate 177Lu-Lilotomab satetraxetan
Blakkisrud, Johan; Holtedahl, Jon Erik; Løndalen, Ayca; Dahle, Jostein; Bach-Gansmo, Tore; Holte, Harald; Nygaard, Stine; Kolstad, Arne; Stokke, Caroline (Journal of Nuclear Medicine;April 1, 2018; Vol. 59, no. 4, Journal article; Peer reviewed, 2018-08-28)177Lu-lilotomab satetraxetan is a novel antibody radionuclide conjugate (ARC) currently in a phase 1/2a first-in-human dosage escalation trial for patients with relapsed CD37+ indolent non Hodgkin lymphoma (NHL). The ... -
Correlations between 68Ga]Ga-DOTA-TOC Uptake and Absorbed Dose from [177Lu]Lu-DOTA-TATE
Bruvoll, Ragnar Bjørn Watte; Blakkisrud, Johan; Mikalsen, Lars Tore Gyland; Connelly, James Pattrick; Stokke, Caroline (Journal article; Peer reviewed, 2023)Purpose: The aim of this paper was to investigate correlations between pre- therapeutic [68Ga]Ga-DOTA-TOC uptake and absorbed dose to tumours from therapy with [177Lu]Lu-DOTA- TATE. Methods: This retrospective study included ... -
The effect of new formulas for lean body mass on lean- body-mass-normalized SUV in oncologic 18F-FDG PET/CT
Halsne, Trygve; Müller, Ebba Gløersen; Spiten, Ann-Eli; Sherwani, Alexander Gul; Mikalsen, Lars Tore G; Rootwelt-Revheim, Mona-Elisabeth; Stokke, Caroline (Journal of Nuclear Medicine Technology;Vol. 46, No. 3, Journal article; Peer reviewed, 2018-03-28)Due to better precision and intercompatibility, the use of lean body mass (LBM) as mass estimate in the calculation of standardized uptake values (SUV) has become more common in research and clinical studies today. Thus, ... -
Myelosuppression in patients treated with 177Lutetium-lilotomab satetraxetan can be predicted with absorbed dose to the red marrow as the only variable
Blakkisrud, Johan; Løndalen, Ayca; Dahle, Jostein; Martinsen, Anne Catrine Trægde; Kolstad, Arne; Stokke, Caroline (Acta Oncologica;Volume 60, 2021 - Issue 11, Peer reviewed; Journal article, 2021-08-23)Background: The aim of this study was to investigate dosimetry data and clinical variables to predict hematological toxicity in non-Hodgkin lymphoma (NHL) patients treated with [177Lutetium]Lu-liloto-mab satetraxetan. Material ... -
New distinct compartments in the G2 phase of the cell cycle defined by the levels of γH2AX.
Rein, Idun Dale; Stokke, Caroline; Jalal, Marwa; Myklebust, June H.; Patzke, Sebastian; Stokke, Trond (Cell Cycle;14(20), Journal article; Peer reviewed, 2015-08-28)Induction of DNA double strand breaks leads to phosphorylation and focus-formation of H2AX. However, foci of phosphorylated H2AX (γH2AX) appear during DNA replication also in the absence of exogenously applied injury. We ... -
Optimalisering av FDG- PET/CT for pasienter med lymfekreft
Sadraddin, Nahla (Master thesis, 2021)Sammendrag Bakgrunn Positronemisjonstomografi (PET) med 18-F fluorodeoksyglukose (FDG), integrert med computertomografi (CT)- (18F- FDG- PET / CT) blir i økende grad brukt til klassifisering og i oppfølgingsvurderingen ... -
Optimalisering av FDG- PET/CT for pasienter med lymfom
Sadraddin, Nahla (Master thesis, 2021-05)Bakgrunn Positronemisjonstomografi (PET) med 18-F fluorodeoksyglukose (FDG), integrert med computertomografi (CT)- (18F- FDG- PET / CT) blir i økende grad brukt til klassifisering og i oppfølgingsvurderingen av behandlingsrespons ... -
Optimized SPECT Imaging of 224Ra α-Particle Therapy by 212Pb Photon Emissions
Mikalsen, Lars Tore Gyland; Kvassheim, Monika; Stokke, Caroline (Peer reviewed; Journal article, 2023)In preparation for an a-particle therapy trial using 1–7 MBq of 224Ra, the feasibility of tomographic SPECT/CT imaging was of interest. The nuclide decays in 6 steps to stable 208Pb, with 212Pb as the principle photon-emitting ... -
Pre-dosing with lilotomab prior to therapy with 177Lu-lilotomab satetraxetan significantly increases the ratio of tumor to red marrow absorbed dose in non-Hodgkin lymphoma patients
Stokke, Caroline; Blakkisrud, Johan; Løndalen, Ayca; Dahle, Jostein; Martinsen, Anne Catrine Trægde; Holte, Harald; Kolstad, Arne (European Journal of Nuclear Medicine and Molecular Imaging;July 2018, Volume 45, Issue 7, Journal article; Peer reviewed, 2018-02-22)Purpose: 177Lu-lilotomab satetraxetan is a novel anti-CD37 antibody radionuclide conjugate for the treatment of non-Hodgkin lymphoma (NHL). Four arms with different combinations of pre-dosing and pre-treatment have been ... -
Respiratory motion during 90Yttrium PET contributes to underestimation of tumor dose and overestimation of normal liver tissue dose.
Ausland, Line; Revheim, Mona-Elisabeth; Skretting, Arne; Stokke, Caroline (Journal article; Peer reviewed, 2017)Background Yttrium-90 dosimetry after radioembolization is reliant on accurate quantitative imaging of the microsphere deposition. Previous studies have focused on the correction of geometrical resolution effects. Pu ... -
Scar imaging in the dyssynchronous left ventricle: Accuracy of myocardial metabolism by positron emission tomography and function by echocardiographic strain
Larsen, Camilla Kjellstad; Galli, Elena; Duchenne, Jürgen; Aalen, John; Stokke, Caroline; Fjeld, Jan Gunnar; Degtiarova, Ganna; Claus, Piet; Gheysens, Olivier; Saberniak, Jørg; Sirnes, Per Anton; Lyseggen, Erik; Bogaert, Jan; Kongsgaard, Erik; Penicka, Martin; Voigt, Jens-Uwe; Donal, Erwan; Hopp, Einar; Smiseth, Otto Armin (Peer reviewed; Journal article, 2022)