• Bridging the polar and hydrophobicmMetabolome in single-run untargeted liquid chromatography-mass spectrometry dried blood spot metabolomics for clinical purposes 

      Skogvold, Hanne Bendiksen; Sandås, Elise Mørk; Østeby, Anja; Løkken, Camilla; Rootwelt, Helge; Rønning, Per Ola; Wilson, Steven Ray Haakon; Elgstøen, Katja Benedikte Prestø (Peer reviewed; Journal article, 2021)
      Dried blood spot (DBS) metabolite analysis is a central tool for the clinic, e.g., newborn screening. Instead of applying multiple analytical methods, a single liquid chromatography-mass spectrometry (LC–MS) method was ...
    • A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics 

      Skogvold, Hanne Bendiksen; Yazdani, Mazyar; Mørk Sandås, Elise; Østeby, Anja; Kristensen, Erle; Haarr, Dagfinn; Rootwelt, Helge; Elgstøen, Katja B. Prestø (Peer reviewed; Journal article, 2021)
      The neurotoxin 3-nitropropionic acid (3-NPA) is an inhibitor of succinate dehydrogenase, an enzyme participating both in the citric acid cycle and the mitochondrial respiratory chain. In human intoxications, it produces ...
    • Tear metabolomics in dry eye disease: A review 

      Yazdani, Mazyar; Elgstøen, Katja B. Prestø; Rootwelt, Helge; Shahdafar, Aboulghassem; Utheim, Øygunn Aass; Utheim, Tor Paaske (International Journal of Molecular Sciences;Volume 20, Issue 15, Journal article; Peer reviewed, 2019-08-01)
      Dry eye disease (DED) is a multifactorial syndrome that can be caused by alteration in the quality or quantity of the precorneal tear film. It is considered one of the most common ocular conditions leading patients to seek ...