Browsing ODA Open Digital Archive by Author "Ringstad, Geir"
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Brain-wide glymphatic enhancement and clearance in humans assessed with MRI
Ringstad, Geir; Valnes, Lars Magnus; Dale, Anders; Pripp, Are Hugo; Vatnehol, Svein Are Sirirud; Emblem, Kyrre Eeg; Mardal, Kent-Andre; Eide, Per Kristian (JCI Insight;Volume 3, Issue 13, Journal article; Peer reviewed, 2018-07-12)To what extent does the subarachnoid cerebrospinal fluid (CSF) compartment communicate directly with the extravascular compartment of human brain tissue? Interconnection between the subarachnoid CSF compartment and brain ... -
Impaired glymphatic function in idiopathic intracranial hypertension
Eide, Per Kristian; Pripp, Are Hugo; Ringstad, Geir; Valnes, Lars Magnus (Brain Communications;Volume 3, Issue 2, Peer reviewed; Journal article, 2021-03-21)Idiopathic intracranial hypertension is a brain disease incorporating cerebrospinal fluid disturbance, increased intracranial pressure and visual failure, but with unknown cause. This study examined a hypothesis that ... -
In vivo distribution of cerebrospinal fluid tracer in human upper spinal cord and brain stem
Melin, Erik; Pripp, Are Hugo; Eide, Per Kristian; Ringstad, Geir (Peer reviewed; Journal article, 2023)BACKGROUND. Intrathecal injection is an attractive route through which drugs can be administered and directed to the spinal cord, restricted by the blood-spinal cord barrier. However, in vivo data on the distribution of ... -
Physiological alterations of pineal recess crowding in symptomatic non-hydrocephalic pineal cysts
Eide, Per Kristian; Lindstrøm, Erika Kristina; Pripp, Are Hugo; Valnes, Lars Magnus; Ringstad, Geir (Peer reviewed; Journal article, 2023)Pineal cysts are prevalent in the population. Due to more widespread use of magnetic resonance imaging, an increasing number of symptomatic patients with non-hydrocephalic pineal cysts are referred to neurologists and ... -
Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders
Eide, Per Kristian; Lashkarivand, Aslan; Pripp, Are Hugo; Valnes, Lars Magnus; Hovd, Markus Herberg; Ringstad, Geir; Blennow, Kaj; Zetterberg, Henrik (Peer reviewed; Journal article, 2023)Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently emerged to be crucial, and plasma biomarkers of neurodegen- eration were newly introduced to predict neurological disease. This ... -
Prevalence of pineal cysts in healthy individuals: Emphasis on size, morphology and pineal recess crowding
Warsza, Bogna; Due-Tønnessen, Pernille; Due-Tønnessen, Paulina; Pripp, Are Hugo; Ringstad, Geir; Eide, Per Kristian (Peer reviewed; Journal article, 2023)The present study aimed to determine prevalence of non-hydrocephalic pineal cysts of different size and morphology in healthy individuals. In a cohort of healthy individuals who as part of research volunteered to undergo ... -
Prospective T1 mapping to assess gadolinium retention in brain after intrathecal gadobutrol
Ringstad, Geir; Valnes, Lars Magnus; Vatnehol, Svein Are Sirirud; Pripp, Are Hugo; Eide, Per Kristian (Peer reviewed; Journal article, 2023)Purpose A possible pathway behind gadolinium retention in brain is leakage of contrast agents from blood to cerebrospi- nal fluid and entry into brain along perivascular (glymphatic) pathways. The object of this study was ...