Browsing ODA Open Digital Archive by Author "Pedersen, Linda Margareth"

Now showing items 1-12 of 12

    • Assosiasjon mellom baselinekarakteristika og bensmerte 6 uker etter sykehusinnleggelse hos konservativt eller kirurgisk behandlede isjiaspasienter. 

      Fossholt, Ingunn (MAFYS;2020, Master thesis, 2020)
      Hensikt: Forskning på faktorer assosiert med bensmerte på kort sikt for isjiaspasienter er mangelfull. Hensikten var å kartlegge smerteutvikling og baselinefaktorer assosiert med bensmerter etter 6 uker for konservativt ...

    • COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study 

      Jacobsen, Kaya Kvarme; Børte, Sigrid; Laborie, Lene Bjerke; Kristiansen, Hege; Schäfer, Annette; Gundersen, Trude; Zayats, Tetyana; Winsvold, Bendik Kristoffer Slagsvold; Karen, Rosendahl; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Fors, Egil Andreas; Kristoffersen, Espen Saxhaug; Heuch, Ingrid; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Nielsen, Jonas B.; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars G; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Lie, Marie U.; Stensland, Synne; Zhou, Wei (Peer reviewed; Journal article, 2023)
      Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ...

    • Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement 

      Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Kristoffersen, Per Martin; Vetti, Nils; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Schistad, Ellina Iordanova; Haugen, Anne Julsrud; Johanessen, Anne Froholdt; Skouen, Jan Sture; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Lie, Benedicte Alexandra (Scientific Reports;12, Article number: 215 (2022), Peer reviewed; Journal article, 2022-01-07)
      Disability and distress caused by chronic low back pain (LBP) lacking clear pathoanatomical explanations cause huge problems both for patients and society. A subgroup of patients has Modic changes (MC), identifable by MRI ...

    • Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study) 

      Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Gervin, Kristina; Pripp, Are Hugo; Skouen, Jan Sture; Schistad, Elina Iordanova; Pedersen, Linda Margareth; Wigemyr, Monica; Selmer, Kaja Kristine; Dalsbotten Aass, Hans Christian; Goll, Guro Løvik; Brox, Jens Ivar; Espeland, Ansgar; Grøvle, Lars; Zwart, John Anker Henrik; Storheim, Kjersti (Peer reviewed; Journal article, 2023)
      Objective: Randomized trials testing the effect of antibiotics for chronic low back pain (LBP) with vertebral bone marrow changes on MRI (Modic changes) report inconsistent results. A proposed explanation is subgroups ...

    • Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity 

      Bakker, Mark K.; Kanning, Jos P.; Abraham, Gad; Martinsen, Amy; Winsvold, Bendik Kristoffer Slagsvold; Zwart, John Anker Henrik; Bourcier, Romain; Sawada, Tomonobu; Koido, Masaru; Kamatani, Yoichiro; Morel, Sandrine; Amouyel, Philippe; Debette, Stéphanie; Bijlenga, Philippe; Berrandou, Takiy; Ganesh, Santhi K.; Bouatia-Naji, Nabila; Jones, Gregory; Bown, Matthew; Rinkel, Gabriel J.E.; Veldink, Jan H.; Ruigrok, Ynte M.; Aamodt, Anne Hege; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Sandset, Else Charlotte; Kristoffersen, Espen Saxhaug; Ellekjær, Hanne; Heuch, Ingrid; Nielsen, Jonas Bille; Hagen, Knut; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Holmen, Oddgeir Lingaas; Børte, Sigrid; Schmidt, Helena; Stubhaug, Audun; Nielsen, Christopher Sivert; Johnsen, Marianne Bakke; Sandvei, Marie Søfteland (Peer reviewed; Journal article, 2023)
      BACKGROUND: Recently, common genetic risk factors for intracranial aneurysm (IA) and aneurysmal subarachnoid hemorrhage (ASAH) were found to explain a large amount of disease heritability and therefore have potential to ...

    • Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions 

      Khoury, Samar; Parisien, Marc; Thompson, Scott J.; Vachon-Presseau, Etienne; Roy, Mathieu; Mitchell, Amy; Winsvold, Bendik K S; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Fors, Egil Andreas; Heuch, Ingrid; Nielsen, Jonas Bille; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Kania, Artur; Mogil, Jeffrey S.; Diatchenko, Luda (Brain;Volume 145, Issue 3, Peer reviewed; Journal article, 2021-11-11)
      Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is ...

    • Hva eksisterer av kilder på Arbeidsdeltakelse hos sykmeldte med muskel- og skjelettlidelser under ordningen Raskere tilbake: en scoping review 

      Remøy, Paul (Master thesis, 2021)
      Bakgrunn: Det brukes milliarder av kroner på permanent og midlertidig uførhet i Norge og det er angitt at behovet for arbeidskraft vil overstige den tilgjengelige i fremtiden. Muskel- og skjelettlidelser er et stort nasjonalt ...

    • Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes 

      Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Zucknick, Manuela; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Selmer, Kaja Kristine; Lie, Benedicte Alexandra; Gervin, Kristina (Peer reviewed; Journal article, 2023)
      Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We con- ducted longitudinal transcriptome ...

    • Longitudinal changes of serum cytokines in patients with chronic low back pain and Modic changes 

      Gjefsen, Elisabeth; Gervin, Kristina; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Aass, Hans Christian; Schistad, Elina Iordanova; Wigemyr, Monica; Pedersen, Linda Margareth; Skouen, Jan Sture; Vigeland, Maria Dehli; Selmer, Kaja Kristine; Storheim, Kjersti; Zwart, John Anker Henrik (Peer reviewed; Journal article, 2023)
      Objectives: To explore serum cytokine levels over time in patients with chronic low back pain (cLBP) and Modic changes (MCs), difference in change between treatment groups in the Antibiotics in Modic Changes (AIM) study ...

    • Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC 

      Lie, Marie; Pedersen, Linda Margareth; Heuch, Ingrid; Winsvold, Bendik K S; Gjerstad, Johannes; Hasvik, Eivind Olay; Nygaard, Øystein Petter; Grotle, Margreth; Matre, Dagfinn; Zwart, John Anker Henrik; Nilsen, Kristian Bernhard (Frontiers in Genetics;January 2022 | Volume 12 | Article 757632, Peer reviewed; Journal article, 2022-01-24)
      In a recently published genome-wide association study (GWAS) chronic back pain was associated with three loci; SOX5, CCDC26/GSDMC and DCC. This GWAS was based on a heterogeneous sample of back pain disorders, and it is ...

    • Macrophage migration inhibitory factor: A potential biomarker for chronic low back pain in patients with Modic changes 

      Gjefsen, Elisabeth; Gervin, Kristina; Goll, Guro Løvik; Bråten, Lars Christian Haugli; Wigemyr, Monica; Aass, Hans Christian Dalsbotten; Vigeland, Maria Dehli; Schistad, Ellina Iordanova; Pedersen, Linda Margareth; Pripp, Are Hugo; Storheim, Kjersti; Selmer, Kaja Kristine; Zwart, John Anker (RMD Open;Volume 7, Issue 2, Peer reviewed; Journal article, 2021-08-03)
      Background: Low back pain (LBP) is a leading cause of disability worldwide, but the aetiology remains poorly understood. Finding relevant biomarkers may lead to better understanding of disease mechanisms. Patients with ...

    • Validation of the Norwegian pain sensitivity questionnaire 

      Valeberg, Berit Taraldsen; Pedersen, Linda Margareth; Girotto, Valentina; Christensen, Vivi Lycke; Stubhaug, Audun (Journal article; Peer reviewed, 2017)
      Background and purpose: There is a large variation in people’s reactions to painful stimuli. Although some conditions are more painful, the variation between people is larger than the reaction to pain across conditions. ...