Browsing ODA Open Digital Archive by Author "Lund, Jenny"

Now showing items 1-4 of 4

    • Blodglukosesenkende ­legemidler ved type 2-diabetes 

      Aas, Vigdis; Lund, Jenny; Kase, Eili T.; Feng, Yuan Z.; Rustan, Arild C.; Thoresen, Hege (Norsk Farmaceutisk Tidsskrift;5, Journal article; Peer reviewed, 2015)
      Hensikt Denne artikkelen gir en oversikt over tilgjengelige legemidler, foruten insulin, til behandling av hyperglykemi ved type 2-diabetes. De enkelte legemidlenes virkningsmekanisme, kliniske effekt og bruk, samt ...

    • Increased glycolysis and higher lactate production in hyperglycemic myotubes 

      Lund, Jenny; Ouwens, DM; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege; Aas, Vigdis (Cells;Volume 8, Issue 9, Journal article; Peer reviewed, 2019-09-18)
      Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial ...

    • Substrate oxidation in primary human skeletal muscle cells is influenced by donor age 

      Aas, Vigdis; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny (Cell and Tissue Research;382 (2020), Journal article; Peer reviewed, 2020-09-08)
      Primary human myotubes represent an alternative system to intact skeletal muscle for the study of human diseases related to changes in muscle energy metabolism. This work aimed to study if fatty acid and glucose metabolism ...

    • Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism 

      Lund, Jenny; Aas, Vigdis; Tingstad, Ragna Husby; Van Hees, Alfons; Nikolic, Natasa (Scientific Reports;8, Article number: 9814 (2018), Journal article; Peer reviewed, 2018-06-29)
      Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular ...