Browsing ODA Open Digital Archive by Author "Leder, Lena"
Now showing items 1-5 of 5
-
Beneficial effect on serum cholesterol levels, but not glycaemic regulation, after replacing SFA with PUFA for three days: a randomised crossover trial
Gaundal, Line; Myhrstad, Mari; Leder, Lena; Byfuglien, Marte Gjeitung; Gjøvaag, Terje; Rud, Ida; Retterstøl, Kjetil; Holven, Kirsten Bjørklund; Ulven, Stine Marie; Telle-Hansen, Vibeke (British Journal of Nutrition;, Journal article; Peer reviewed, 2020-09-02)Replacing intake of SFA with PUFA reduces serum cholesterol levels and CVD risk. The effect on glycaemic regulation is, however, less clear. The main objective of the present study was to investigate the short-term effect ... -
Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: A SYSDIET sub-study
Leder, Lena; Kolehmainen, Marjukka; Narverud, Ingunn; Dahlman, Ingrid; Myhrstad, Mari; De Mello, Vanessa D.; Paananen, Jussi; Carlberg, Carsten; Schwab, Ursula; Herzig, Karl-Heinz; Cloetens, Lieselotte; Storm, Matilda Ulmius; Hukkanen, Janne; Savolainen, Markku J.; Rosqvist, Fredrik; Hermansen, Kjeld; Dragsted, Lars O.; Gunnarsdóttir, Ingibjörg; Thórsdóttir, Inga; Risérus, Ulf; Åkesson, Björn; Thoresen, Magne; Arner, Peter; Poutanen, Kaisa S.; Uusitupa, Matti; Holven, Kirsten Bjørklund; Ulven, Stine Marie (Journal article; Peer reviewed, 2016)Background: Diet has a great impact on the risk of developing features of metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). We evaluated whether a long-term healthy Nordic ... -
Exchanging a few commercial, regularly consumed food items with improved fat quality reduces total cholesterol and LDL-cholesterol: A double-blind, randomised controlled trial
Ulven, Stine Marie; Leder, Lena; Elind, Elisabeth; Ottestad, Inger; Christensen, Jacob J.; Telle-Hansen, Vibeke; Skjetne, Anne Juul; Raael, Ellen; Sheikh, Navida Akhter; Holck, Marianne; Torvik, Kristin; Lamglait, Amandine; Thyholt, Kari; Byfuglien, Marte Gjeitung; Granlund, Linda; Andersen, Lene Frost; Holven, Kirsten Bjørklund (Journal article; Peer reviewed, 2016)The healthy Nordic diet has been previously shown to have health bene fi cial effects among subjects at risk of CVD. However, the extent of food changes needed to achieve these effects is less explored. The aim of the ... -
An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome—A SYSDIET Sub-Study
Ulven, Stine Marie; Holven, Kirsten Bjørklund; Rundblad, Amanda; Myhrstad, Mari; Leder, Lena; Dahlman, Ingrid; De Mello, Vanessa D.; Schwab, Ursula; Carlberg, Carsten; Pihlajamaki, Jussi; Hermansen, Kjeld; Dragested, Lars; Gunnarsdottir, Ingibjørg; Cloetens, Lieselotte; Åkesson, Bjørn; Rosqvist, Fredrik; Hukkanen, Janne; Herzig, Karl-Heinz; Savolainen, Markku J.; Risérus, Ulf; Thorsdottir, Inga; Poutanen, Kaisa S.; Arner, Peter; Uusitupa, Matti; Kolehmainen, Marjukka (Nutrients;Volume 11, Issue 12, Journal article; Peer reviewed, 2019-12-03)A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the ... -
Replacing saturated fat with polyunsaturated fat modulates peripheral blood mononuclear cell gene expression and pathways related to cardiovascular disease risk using a whole transcriptome approach
Larsen, Sunniva Veen; Holven, Kirsten B.; Christensen, Jacob J.; Flatberg, Arnar; Rundblad, Amanda; Leder, Lena; Blomhoff, Rune; Telle-Hansen, Vibeke; Kolehmainen, Marjukka; Carlberg, Carsten; Myhrstad, Mari C.; Thoresen, Magne; Ulven, Stine M. (Peer reviewed; Journal article, 2021)Scope The aim of this study is to explore the molecular mechanisms underlying the effect of replacing dietary saturated fat (SFA) with polyunsaturated fat (PUFA) on cardiovascular disease (CVD) risk using a whole transcriptome ...