Blar i ODA Open Digital Archive på forfatter "Karlsson, Robert"
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Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: a case–parent triad study in a Norwegian–Swedish population
Kristiansen, Wenche; Andreassen, Kristine Engen; Karlsson, Robert; Aschim, Elin Leirvoll; Bremnes, Roy M.; Dahl, Olav; Fosså, Sophie Dorothea; Klepp, Olbjørn; Langberg, Carl W.; Solberg, Arne; Tretli, Steinar; Adami, Hans-Olov; Wiklund, Fredrik; Grotmol, Tom; Haugen, Trine Berit (Human Reproduction;27 (5), Journal article; Peer reviewed, 2012-03-08)BACKGROUND Testicular germ cell tumour (TGCT) is the most common cancer in young men, and an imbalance between the estrogen and androgen levels in utero is hypothesized to influence TGCT risk. Thus, polymorphisms in genes ... -
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
Litchfield, Kevin; Levy, Max; Orlando, Giulia; Loveday, Chey; Law, Philip J.; Migliorini, Gabriele; Holroyd, Amy; Broderick, Peter; Karlsson, Robert; Haugen, Trine B.; Kristiansen, Wenche; Nsengimana, Jérémie; Fenwick, Kerry; Assiotis, Ioannis; Kote-Jarai, Zsofia; Dunning, Alison M.; Muir, Kenneth; Peto, Julian; Eeles, Rosalind; Easton, Douglas F.; Dudakia, Darshna; Orr, Nick; Pashayan, Nora; Bishop, D. Timothy; Reid, Alison; Huddart, Robert A.; Shipley, Janet; Grotmol, Tom; Wiklund, Fredrik; Houlston, Richard S.; Turnbull, Clare (Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)Genome-wide association studies (GWAS) have transformed our understanding of testicular germ cell tumour (TGCT) susceptibility but much of the heritability remains unexplained. Here we report a new GWAS, a meta-analysis ... -
Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor
Wang, Zhaoming; McGlynn, Katherine A.; Rajpert-De Meyts, Ewa; Bishop, D. Timothy; Chung, Charles C.; Dalgaard, Marlene D.; Greene, Mark H.; Gupta, Ramneek; Grotmol, Tom; Haugen, Trine B.; Karlsson, Robert; Litchfield, Kevin; Mitra, Nandita; Nielsen, Kasper; Pyle, Louise C.; Schwartz, Stephen M.; Thorsson, Vesteinn; Vardhanabhuti, Saran; Wiklund, Fredrik; Turnbull, Clare; Chanock, Stephen J.; Kanetsky, Peter A.; Nathanson, Katherine L. (Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)The international TEsticular CAncer Consortium (TECAC) combined five published genome-wide association studies of testicular germ cell tumors (TGCT; 3,558 cases and 13,970 controls) to identify novel susceptibility loci. ...