Browsing ODA Open Digital Archive by Author "Kaasa, Stein"
Now showing items 1-12 of 12
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Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial
Solheim, Tora Skeidsvoll; Laird, Barry J. A.; Balstad, Trude Rakel; Bye, Asta; Stene, Guro Birgitte; Baracos, Vickie; Strasser, Florian; Griffiths, Gareth; Maddocks, Matthew; Fallon, Marie; Kaasa, Stein; Fearon, Kenneth (BMJ Supportive & Palliative Care;Volume 8, Issue 3, Journal article; Peer reviewed, 2018-02-09)Cancer cachexia is a multifactorial syndrome characterized by an on-going loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer ... -
Deterioration in Muscle Mass and Physical Function Differs According to Weight loss History in Cancer Cachexia
Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Cancers;Volume 11, Issue 12, Journal article; Peer reviewed, 2019-11-22)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ... -
Deterioration in muscle mass and physical function differs according to weight loss history in cancer cachexia
Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Cancers 2019;11(12), Journal article; Peer reviewed, 2019)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ... -
Dietary treatment of weight loss in patients with advanced cancer and cachexia: A systematic literature review
Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Strasser, Florian; Kaasa, Stein; Bye, Asta (Journal article; Peer reviewed, 2014-08)Purpose A systematical literature review evaluating the effect of dietary counseling in treating weight loss and improving energy intake in patients with advanced cancer with different stages of cachexia. Principal ... -
Food intake by Patient-Generated Subjective Global Assessment (PG-SGA) corresponds to energy and protein intake as well as weight change in patients with advanced cancer
Bye, Asta; Meli, Kari; Solheim, Tora Skeidsvoll; Laird, Barry J; Kaasa, Stein; Stene, Guro Birgitte; Balstad, Trude Rakel (Clinical Nutrition Experimental; Volume 25, June 2019, Journal article; Peer reviewed, 2019)Background & aims The aim of this study was to test how well the Patient-Generated Subjective Global Assessment (PG-SGA) question about food intake correlates with a well-established measurement of food intake. Furthermore, ... -
Norwegian reference values for the Short-Form Health Survey 36: development over time
Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2017)Purpose Reference values for patient-reported outcome measures are useful for interpretation of results from clinical trials. The study aims were to collect Norwegian SF-36 reference values and compare with data from ... -
Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
McDonald, James; Sayers, Judith; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Baracos, Vickie; Brown, Leo; Bye, Asta; Dajani, Olav; Dolan, Ross; Fallon, Marie T.; Fraser, Eilidh; Griel, Christine; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jamal-Hanjani, Mariam; Jakobsen, Gunnhild; Kaasa, Stein; McMillan, Donald; Maddocks, Matthew; Philips, Iain; Ottestad, Inger; Reid, Kieran F.; Sousa, Mariana S.; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Skipworth, Richard J. E.; Solheim, Tora S; Laird, Barry J (Peer reviewed; Journal article, 2023)In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, ... -
Physical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program
Sandmæl, Jon Arne; Bye, Asta; Solheim, Tora S; Balstad, Trude Rakel; Thorsen, Lene; Skovlund, Eva; Kaasa, Stein; Lund, Jo-Åsmund; Oldervoll, Line Merethe (Laryngoscope Investigative Otolaryngology;Volume 5, Issue 2, Journal article; Peer reviewed, 2020-03-17)Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality of life (HRQoL) in patients with head and neck cancer. The objective was to assess development in relevant ... -
Power comparisons and clinical meaning of outcome measures in assessing treatment effect in cancer cachexia: secondary analysis from a randomised pilot multimodal intervention trial
Balstad, Trude Rakel; Brunelli, Cinzia; Pettersen, Caroline Hild; Schønberg, Svanhild Margrethe Arentz; Skorpen, Frank; Fallon, Marie T.; Kaasa, Stein; Bye, Asta; Laird, Barry J. A.; Stene, Guro Birgitte; Solheim, Tora Skeidsvoll (Frontiers in Nutrition; January 2021 | Volume 7 | Article 602775, Journal article; Peer reviewed, 2020-01-14)Background: New clinical trials in cancer cachexia are essential, and outcome measures with high responsiveness to detect meaningful changes are crucial. This secondary analysis from a multimodal intervention trial estimates ... -
A randomized phase II feasibility trial of a multimodal intervention for the management of cachexia in lung and pancreatic cancer
Solheim, Tora Skeidsvoll; Laird, Barry J; Balstad, Trude Rakel; Stene, Guro Birgitte; Bye, Asta; Johns, Neil; Pettersen, Caroline Hild Hakvåg; Fallon, Marie; Fayers, Peter; Fearon, Kenneth; Kaasa, Stein (Journal article; Peer reviewed, 2017)Background Cancer cachexia is a syndrome of weight loss (including muscle and fat), anorexia, and decreased physical function. It has been suggested that the optimal treatment for cachexia should be a multimodal ... -
Ten-year survival after High-Dose-Rate Brachytherapy combined with External Beam Radiation Therapy in high-risk prostate cancer: A comparison with the Norwegian SPCG-7 cohort
Wedde, Trude Baastad; Småstuen, Milada Cvancarova; Brabrand, Sigmund; Fosså, Sophie Dorothea; Kaasa, Stein; Tafjord, Gunnar; Russnes, Kjell Magne; Hellebust, Taran Paulsen; Lilleby, Wolfgang (Radiotherapy and Oncology;Volume 132, March 2019, Journal article; Journal article; Peer reviewed, 2018-10-30)Background: The survival benefit of dose-escalation with High-Dose-Rate brachytherapy (HDR-BT) combined with External Beam Radiotherapy (EBRT) for the treatment of high-risk prostate cancer (PCa) remains debatable. We ... -
Validation of Doloplus-2 among nonverbal nursing home patients : an evaluation of Doloplus-2 in a clinical setting
Torvik, Karin; Kaasa, Stein; Kirkevold, Øyvind; Saltvedt, Ingvild; Hølen, Jacob Christian; Fayers, Peter; Rustøen, Tone (BMC Geriatrics;10 (9), Journal article; Peer reviewed, 2010-02-20)Background: Pain measurement in nonverbal older adults is best based on behavioural observation, e.g. using an observational measurement tool such as Doloplus-2. The purposes of this study were to examine the use ...