• Body Mass Index Is Associated with Impaired Semen Characteristics and Reduced Levels of Anti-Müllerian Hormone across a Wide Weight Range 

      Andersen, Jorunn Marie; Herning, Hilde; Aschim, Elin L.; Hjelmesæth, Jøran; Mala, Tom; Hanevik, Hans Ivar; Bungum, Mona; Haugen, Trine B.; Witczak, Oliwia (PloS one;10(6), Journal article; Peer reviewed, 2015-06-12)
      There is still controversy as to how body mass index (BMI) affects male reproduction. We investigated how BMI is associated with semen quality and reproductive hormones in 166 men, including 38 severely obese men. Standard ...
    • Bone Turnover Markers After Standard and Distal Roux-en-Y Gastric Bypass: Results from a Randomized Controlled Trial 

      Svanevik, Marius; Risstad, Hilde; Hofsø, Dag; Høgestøl, Ingvild Kristine; Kristinsson, Jon Adalsteinn; Sandbu, Rune; Småstuen, Milada Cvancarova; Thorsby, Per Medbøe; Mala, Tom; Hjelmesæth, Jøran (Obesity Surgery;29, pages 2886–2895 (2019), Journal article; Peer reviewed, 2019-05-08)
      Background: Roux-en-Y gastric bypass is associated with increased risk of bone fractures. Malabsorptive procedures may be associated with secondary hyperparathyroidism and detrimental effects on bone health. We aimed to ...
    • Camp-based family treatment of childhood obesity: randomised controlled trial 

      Benestad, Beate; Lekhal, Samira; Småstuen, Milada C; Hertel, Jens Kristoffer; Halsteinli, Vidar; Ødegård, Rønnaug Astri; Hjelmesæth, Jøran (Archives of Disease in Childhood;volume 102, issue 4, Peer reviewed; Journal article, 2017-03-20)
      Objective To compare the effectiveness of a 2-year camp-based family treatment programme and an outpatient programme on obesity in two generations. Design Pragmatic randomised controlled trial. Setting Rehabilitation ...
    • Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes 

      Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria; Hjelmesæth, Jøran; Sandbu, Rune; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Jansson-Löfmark, Rasmus; Karlsson, Cecilia; Andersson, Shalini; Åsberg, Anders; Andersson, Tommy B.; Christensen, Hege Staaland (Journal of Pharmaceutical Sciences;Volume 110, Issue 1, Journal article; Peer reviewed, 2020-10-18)
      Obesity is associated with comorbidities of which pharmacological treatment is needed. Physiological changes associated with obesity may influence the pharmacokinetics of drugs, but the effect of body weight on drug ...
    • Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial 

      Hofsø, Dag; Fatima, Farhat; Borgeraas, Heidi; Birkeland, Kåre I.; Gulseth, Hanne Løvdal; Hertel, Jens Kristoffer; Johnson, Line Kristin; Lindberg, Morten; Nordstrand, Njord; Småstuen, Milada Cvancarova; Stefanovski, Darko; Svanevik, Marius; Valderhaug, Tone Gretland; Sandbu, Rune; Hjelmesæth, Jøran (The Lancet Diabetes and Endocrinology;Volume 7, ISSUE 12, Journal article; Peer reviewed, 2019-10-30)
      Background: The comparative effectiveness of various bariatric procedures on remission of type 2 diabetes remains debated. We aimed to compare the two most commonly used procedures, hypothesising higher remission rates ...
    • Myotubes from Severely Obese Type 2 Diabetic Subjects Accumulate Less Lipids and Show Higher Lipolytic Rate than Myotubes from Severely Obese Non-Diabetic Subjects 

      Bakke, Siril Skaret; Feng, Yuan Zeng; Nikolic, Natasa; Kase, Eili Tranheim; Moro, Cedric; Stensrud, Camilla; Damlien, Lisbeth; Ludahl, Marianne Odnakk; Sandbu, Rune; Solheim, Brita Marie; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (Journal article; Peer reviewed, 2015-03-19)
      About 80% of patients with type 2 diabetes are classified as overweight. However, only about 1/3 of severely obese subjects have type 2 diabetes. This indicates that several se- verely obese individuals may possess certain ...