Blar i ODA Open Digital Archive på forfatter "Hessvik, Nina Pettersen"

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    • Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations 

      Fraser, David; Hessvik, Nina Pettersen; Nikolic, Natasa; Aas, Vigdis; Hanssen, Kristian Folkvord; Bøhn, Siv Kjølsrud; Thoresen, G. Hege; Rustan, Arild (Genes & Nutrition;Online before print, Journal article; Peer reviewed, 2011-10-09)
      The aim of the present work was to study the effects of benfotiamine (S-benzoylthiamine O-monophosphate) on glucose and lipid metabolism and gene expression in differentiated human skeletal muscle cells (myotubes) incubated ...

    • Chronic hyperglycemia reduces substrate oxidation and impairs metabolic switching of human myotubes 

      Aas, Vigdis; Hessvik, Nina Pettersen; Wettergreen, Marianne; Hvammen, Andreas Wensaas; Hallén, Stefan; Thoresen, G. Hege; Rustan, Arild (Biochimica et Biophysica Acta - Molecular Basis of Disease;1812 (1), Journal article; Peer reviewed, 2011-01)
      Skeletal muscle of insulin resistant individuals is characterized by lower fasting lipid oxidation and reduced ability to switch between lipid and glucose oxidation. The purpose of the present study was to examine if chronic ...

    • Metabolic switching of human skeletal muscle cells in vitro 

      Thoresen, G. Hege; Hessvik, Nina Pettersen; Bakke, Siril Skaret; Aas, Vigdis; Rustan, Arild (Prostaglandins leukotrienes and essential fatty acids;85 (5), Journal article; Peer reviewed, 2011-05-05)
      In this review we will focus on external factors that may modify energy metabolism in human skeletal muscle cells (myotubes) and the ability of the myotubes to switch between lipid and glucose oxidation. We describe the ...

    • siRNA screening reveals that SNAP29 contributes to exosome release 

      Hessvik, Nina Pettersen; Sagini, Krizia; Romero, Silvana Angelica Troncoso; Ramirez, Manuel; Rodriguez, Marta; Tutturen, Astrid Elisabeth Voorham; Kvalvaag, Audun Sverre Myrset; Stang, Espen; Brech, Andreas; Sandvig, Kirsten; Llorente, Alicia (Peer reviewed; Journal article, 2023)
      Cells release extracellular vesicles (EVs) of different sizes. Small EVs (< 200 nm) can originate from the fusion of multive- sicular bodies with the plasma membrane, i.e. exosomes, and from budding of the plasma membrane, ...