Blar i ODA Open Digital Archive på forfatter "Bemanian, Vahid"
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The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
Kværner, Ane Sørlie; Birkeland, Einar Elvbakken; Bucher-Johannessen, Cecilie; Vinberg, Elina; Nordby, Jan Inge; Kangas, Harri; Bemanian, Vahid; Ellonen, Pekka; Botteri, Edoardo; Natvig, Erik; Rognes, Torbjørn; Hovig, Eivind; Lyle, Robert; Ambur, Ole Herman; de Vos, Willem M.; Bultman, Scott J; Hjartåker, Anette; Landberg, Rikard; Song, Mingyang; Blix, Hege Salvesen; Ursin, Giske; Randel, Kristin Ranheim; de Lange, Thomas; Hoff, Geir; Holme, Øyvind; Berstad, Paula; Rounge, Trine Ballestad (BMC Cancer;21, Article number: 930 (2021), Peer reviewed; Journal article, 2021-08-18)Background: Colorectal cancer (CRC) screening reduces CRC incidence and mortality. However, current screening methods are either hampered by invasiveness or suboptimal performance, limiting their effectiveness as primary ... -
Cytokinprofil i kolorektale tumorer - med og uten Fusobacterium nucleatum
Alte, Annette Knapskog (Master thesis, 2021)Bakgrunn og formål: Den vanlige oppfatningen er at inflammasjon i kolorektal kreft (CRC) er et resultat av den neoplastiske celleveksten. Det er vist at epitelbarrieren mot tarmlumen kan være svekket i kolorektale tumorer, ... -
Decoding immune-related gene-signatures in colorectal neoplasia
Omran, Thura Akrem; Tunsjø, Hege; Jahanlu, David; Brackmann, Stephan Andreas; Bemanian, Vahid; Sæther, Per Christian (Peer reviewed; Journal article, 2024)Background: Colorectal cancer (CRC) is a significant health issue, with notable incidence rates in Norway. The immune response plays a dual role in CRC, offering both protective effects and promoting tumor growth. This ... -
Detection of colorectal-cancer-associated bacterial taxa in fecal samples using next-generation sequencing and 19 newly established qPCR assays
Senthakumaran, Thulasika; Tannæs, Tone Møller; Moen, Aina Elisabeth Fossum; Brackmann, Stephan Andreas; Jahanlu, David; Rounge, Trine Ballestad; Bemanian, Vahid; Tunsjø, Hege (Peer reviewed; Journal article, 2024)We have previously identified increased levels of distinct bacterial taxa within mucosal biopsies from colorectal cancer (CRC) patients. Following prior research, the aim of this study was to investigate the detection of ... -
Detection of somatic mutations in tumor biopsies and circulating tumor DNA during neoadjuvant endocrine therapy in breast cancer patients
Ranestad, Sofie Flovik (Master thesis, 2024)Background and aim: Breast cancer is one of the most prevalent forms of cancer in the world. About 70% of breast cancer patients have hormone-dependent tumors, determined by estrogen receptor positivity. Endocrine therapy ... -
DNA-ekstraksjon: Mengde er ikke synonymt med mangfold
Tunsjø, Hege; Bemanian, Vahid; Noone, John Christopher (Journal article; Peer reviewed, 2017)For å oppnå gode og representative resultater i molekylærgenetiske analyser, er det viktig at nukleinsyrene som benyttes er av tilstrekkelig kvalitet. Som en del av en større studie om kolerektal kreft, var målet å ... -
Microbial dynamics with CRC progression: a study of the mucosal microbiota at multiple sites in cancers, adenomatous polyps, and healthy controls
Senthakumaran, Thulasika; Moen, Aina Elisabeth Fossum; Tannæs, Tone Møller; Endres, Alexander; Brackmann, Stephan Andreas; Rounge, Trine Ballestad; Bemanian, Vahid; Tunsjø, Hege (Peer reviewed; Journal article, 2023)Accumulating evidence has related the gut microbiota to colorectal cancer (CRC). Fusobacterium nucleatum has repeatedly been linked to colorectal tumorigenesis. The aim of this study was to investigate microbial composition ... -
Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer
Bemanian, Vahid; Noone, John Cristopher; Sauer, Torill; Touma, Joel Joul; Vetvik, Katja K.; Söderberg-Naucler, Cecilia; Lindstrøm, Jonas Christoffer; Bukholm, Ida Rashida Khan; Kristensen, Vessela N.; Geisler, Jürgen (Breast cancer research and treatment;172(2), Journal article; Peer reviewed, 2018-08-21)Purpose We have compared the mutational profiles of human breast cancer tumor samples belonging to all major subgroups with special emphasis on triple-negative breast cancer (TNBC). Our major goal was to identify specific ... -
Species-level verification of Phascolarctobacterium association with colorectal cancer
Bucher-Johannessen, Cecilie; Senthakumaran, Thulasika; Avershina, Ekaterina; Birkeland, Einar Elvbakken; Hoff, Geir Svein; Bemanian, Vahid; Tunsjø, Hege; Rounge, Trine Ballestad (Peer reviewed; Journal article, 2024)We have previously demonstrated an association between increased abundance of Phascolarctobacterium and colorectal cancer (CRC) and adenomas in two independent Norwegian cohorts. Here we seek to verify our previous findings ...