• Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor 

      Litchfield, Kevin; Levy, Max; Orlando, Giulia; Loveday, Chey; Law, Philip J.; Migliorini, Gabriele; Holroyd, Amy; Broderick, Peter; Karlsson, Robert; Haugen, Trine B.; Kristiansen, Wenche; Nsengimana, Jérémie; Fenwick, Kerry; Assiotis, Ioannis; Kote-Jarai, Zsofia; Dunning, Alison M.; Muir, Kenneth; Peto, Julian; Eeles, Rosalind; Easton, Douglas F.; Dudakia, Darshna; Orr, Nick; Pashayan, Nora; Bishop, D. Timothy; Reid, Alison; Huddart, Robert A.; Shipley, Janet; Grotmol, Tom; Wiklund, Fredrik; Houlston, Richard S.; Turnbull, Clare (Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)
      Genome-wide association studies (GWAS) have transformed our understanding of testicular germ cell tumour (TGCT) susceptibility but much of the heritability remains unexplained. Here we report a new GWAS, a meta-analysis ...
    • Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor 

      Wang, Zhaoming; McGlynn, Katherine A.; Rajpert-De Meyts, Ewa; Bishop, D. Timothy; Chung, Charles C.; Dalgaard, Marlene D.; Greene, Mark H.; Gupta, Ramneek; Grotmol, Tom; Haugen, Trine B.; Karlsson, Robert; Litchfield, Kevin; Mitra, Nandita; Nielsen, Kasper; Pyle, Louise C.; Schwartz, Stephen M.; Thorsson, Vesteinn; Vardhanabhuti, Saran; Wiklund, Fredrik; Turnbull, Clare; Chanock, Stephen J.; Kanetsky, Peter A.; Nathanson, Katherine L. (Nature Genetics;Volume 49, Issue 7, Journal article; Peer reviewed, 2017-06-12)
      The international TEsticular CAncer Consortium (TECAC) combined five published genome-wide association studies of testicular germ cell tumors (TGCT; 3,558 cases and 13,970 controls) to identify novel susceptibility loci. ...