Browsing ODA Open Digital Archive by Author "Storheim, Kjersti"
Now showing items 21-40 of 65
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Decompression alone versusdecompression with instrumental fusionthe NORDSTEN degenerativespondylolisthesis trial (NORDSTEN-DS);study protocol for a randomized controlledtrial
Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Lønne, Greger; Indrekvam, Kari; Aaen, Jørn; Grundnes, Oliver; Hellum, Christian (BMC Musculoskeletal Disorders;20:07, Journal article; Peer reviewed, 2018-12-18)Background Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting ... -
Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis
Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten Wang; Storheim, Kjersti; Brox, Jens Ivar; Solberg, Tore; Rekeland, Frode; Franssen, Eric; Weber, Clemens; Brisby, Helena; Grundnes, Oliver; Algaard, Knut; Bøker, Tordis; Banitalebi, Hasan; Indrekvam, Kari; Hellum, Christian (New England Journal of Medicine;Vol. 385, No. 6, Peer reviewed; Journal article, 2021-08-05)Background: In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion. Methods: We conducted ... -
Differential response to prolonged amoxicillin treatment: long-term resilience of the microbiome versus long-lasting perturbations in the gut resistome
Dhariwal, Achal; Bråten, Lars Christian Haugli; Sturød, Kjersti; Salvadori Da Silva, Gabriela; Bargheet, Ahmed; Åmdal, Heidi Aarø; Junges, Roger; Berild, Dag; Zwart, John Anker Henrik; Storheim, Kjersti; Petersen, Fernanda Cristina (Peer reviewed; Journal article, 2023)The collateral impact of antibiotics on the microbiome has attained increasing attention. However, the ecological consequences of long-term antibiotic exposure on the gut microbiome, including anti- biotic resistance, ... -
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
Gjefsen, Elisabeth; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Wigemyr, Monica; Bolstad, Nils; Valberg, Morten; Schistad, Ellina Iordanova; Marchand, Gunn Hege; Granviken, Fredrik; Selmer, Kaja Kristine; Johanessen, Anne Froholdt; Haugen, Anne Julsrud; Dagestad, Magnhild Hammersland; Vetti, Nils; Bakland, Gunnstein; Lie, Benedicte Alexandra; Haavardsholm, Espen A.; Nilsen, Aksel Thuv; Holmgard, Thor Einar; Kadar, Thomas; Kvien, Tore Kristian; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Espeland, Ansgar; Storheim, Kjersti; Zwart, John-Anker (BMC Musculoskeletal Disorders;21, Article number: 698 (2020), Journal article; Peer reviewed, 2020-10-21)Background: Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized ... -
Effectiveness of adding motivational interviewing or a stratified vocational advice intervention to usual case management on return to work for people with musculoskeletal disorders: The MI-NAV randomised controlled trial
Aanesen, Fiona; Grotle, Margreth; Rysstad, Tarjei Langseth; Tveter, Anne Therese; Tingulstad, Alexander; Løchting, Ida; Småstuen, Milada Cvancarova; van Tulder, Maurits W.; Berg, Rigmor; Foster, Nadine E.; Wynne-Jones, Gwenllian; Sowden, Gail; Fors, Egil Andreas; Bagøien, Gunnhild Irene; Hagen, Roger; Storheim, Kjersti; Øiestad, Britt Elin (Occupational and Environmental Medicine;Volume 80, Issue 1, Peer reviewed; Journal article, 2022-11-25)Objectives: To evaluate if adding motivational interviewing (MI) or a stratified vocational advice intervention (SVAI) to usual case management (UC), reduced sickness absence over 6 months for workers on sick leave due to ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Espeland, Ansgar; Wigemyr, Monica; Assmus, Jörg; Froholdt, Anne; Haugen, Anne Julsrud; Marchand, Gunn Hege; Kristoffersen, Per M; Lutro, Olav; Randen, Sigrun; Wilhelmsen, Maja; Winsvold, Bendik K S; Kadar, Thomas; Holmgard, Thor Einar; Vigeland, Maria Dehli; Vetti, Nils; Nygaard, Øystein Petter; Lie, Benedicte Alexandra; Hellum, Christian; Anke, Audny; Grotle, Margreth; Schistad, Ellina Iordanova; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (BMJ; 2019;367:l5654, Journal article; Peer reviewed, 2019-08-29)Objective: To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). Design: ... -
Evaluation of the EQ-5D-3L and 5L versions in low back pain patients
Garratt, Andrew; Furunes, Håvard; Hellum, Christian; Solberg, Tore; Brox, Jens Ivar; Storheim, Kjersti; Johnsen, Lars Gunnar (Health and Quality of Life Outcomes;19:155, Peer reviewed; Journal article, 2021-05-28)Background: The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. ... -
Exposure to traumatic events and use of over-the-counter analgesics in adolescents: cross-sectional findings from the Young-HUNT study
Baumann-Larsen, Monica; Dyb, Grete Anita; Wentzel-Larsen, Tore; Zwart, John Anker Henrik; Storheim, Kjersti; Stensland, Synne Øien Blixt (Peer reviewed; Journal article, 2023)Objective Frequent and increasing use of over-the- counter analgesics (OTCA) among adolescents is a public health concern. Prior research indicates that adolescents exposed to traumatic events may be at increased risk of ... -
Follow-up score, change score or percentage change score for determining clinical important outcome following surgery? An observational study from the Norwegian registry for Spine surgery evaluating patient reported outcome measures in lumbar spinal stenosis and lumbar degenerative spondylolisthesis
Austevoll, Ivar Magne; Gjestad, Rolf; Grotle, Margreth; Solberg, Tore; Brox, Jens Ivar; Hermansen, Erland; Rekeland, Frode; Indrekvam, Kari; Storheim, Kjersti; Hellum, Christian (BMC Musculoskeletal Disorders;20(31), Journal article; Peer reviewed, 2019)Assessment of outcomes for spinal surgeries is challenging, and an ideal measurement that reflects all aspects of importance for the patients does not exist. Oswestry Disability Index (ODI), EuroQol (EQ-5D) and Numeric ... -
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions
Khoury, Samar; Parisien, Marc; Thompson, Scott J.; Vachon-Presseau, Etienne; Roy, Mathieu; Mitchell, Amy; Winsvold, Bendik K S; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Fors, Egil Andreas; Heuch, Ingrid; Nielsen, Jonas Bille; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Kania, Artur; Mogil, Jeffrey S.; Diatchenko, Luda (Brain;Volume 145, Issue 3, Peer reviewed; Journal article, 2021-11-11)Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is ... -
Implementing a Stratified Vocational Advice Intervention for People on Sick Leave with Musculoskeletal Disorders: A Multimethod Process Evaluation
Aanesen, Fiona; Øiestad, Britt Elin; Grotle, Margreth; Løchting, Ida; Solli, Rune; Sowden, Gail; Wynne-Jones, Gwenllian; Storheim, Kjersti; Eik, Hedda (Journal of occupational rehabilitation;, Peer reviewed; Journal article, 2021-10-04)Purpose: To perform a process evaluation of a stratified vocational advice intervention (SVAI), delivered by physiotherapists in primary care, for people on sick leave with musculoskeletal disorders participating in a ... -
Implementing a Stratified Vocational Advice Intervention for People on Sick Leave with Musculoskeletal Disorders: A Multimethod Process Evaluation
Øiestad, Britt Elin; Grotle, Margreth; Løchting, Ida; Solli, Rune; Sowden, Gail; Wynne-Jones, Gwenllian; Storheim, Kjersti; Eik, Hedda (Journal of occupational rehabilitation;, Peer reviewed; Journal article, 2021-10-04)Purpose: To perform a process evaluation of a stratified vocational advice intervention (SVAI), delivered by physiotherapists in primary care, for people on sick leave with musculoskeletal disorders participating in a ... -
Individualized quality of life in patients with low back pain: reliability and validity of the Patient Generated Index
Løchting, Ida; Grotle, Margreth; Storheim, Kjersti; Werner, Erik L.; Garratt, Andrew M. (Journal of Rehabilitation Medicine;46(8), Journal article; Peer reviewed, 2014)Objective: To evaluate the reliability and validity of the improved version of the Patient Generated Index (PGI) in patients with low back pain. Methods: The PGI was administered to 90 patients attending care in 1 of ... -
Kan Start Back Screening Tool predikere funksjonsbegrensinger hos eldre som oppsøker primærhelsetjenesten for behandling av sine ryggsmerter? - En prospektiv kohortstudie med 3 måneders oppfølging
Flugstad, Solveig (MAFYS;2020, Master thesis, 2020)Bakgrunn: Psykososiale faktorer er identifisert som spesielt viktige i utviklingen fra akutte til langvarige ryggsmerter. Start Back Screening Tool (SBT) er et screeninginstrument som har til hensikt å klassifisere personer ... -
Killing pain? A prospective population-based study on trauma exposure in childhood as predictor for frequent use of over-the-counter analgesics in young adulthood. The HUNT study
Baumann-Larsen, Monica; Zwart, John Anker Henrik; Dyb, Grete Anita; Wentzel-Larsen, Tore; Stangeland, Helle; Storheim, Kjersti; Stensland, Synne Øien Blixt (Peer reviewed; Journal article, 2023)Frequent and increasing use of over-the-counter analgesics (OTCA) is a public health concern. Pain conditions and psychological distress are related to frequent OTCA use, and as exposure to potentially traumatic events (PTE) ... -
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Zucknick, Manuela; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Selmer, Kaja Kristine; Lie, Benedicte Alexandra; Gervin, Kristina (Peer reviewed; Journal article, 2023)Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We con- ducted longitudinal transcriptome ... -
Longitudinal changes of serum cytokines in patients with chronic low back pain and Modic changes
Gjefsen, Elisabeth; Gervin, Kristina; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Aass, Hans Christian; Schistad, Elina Iordanova; Wigemyr, Monica; Pedersen, Linda Margareth; Skouen, Jan Sture; Vigeland, Maria Dehli; Selmer, Kaja Kristine; Storheim, Kjersti; Zwart, John Anker Henrik (Peer reviewed; Journal article, 2023)Objectives: To explore serum cytokine levels over time in patients with chronic low back pain (cLBP) and Modic changes (MCs), difference in change between treatment groups in the Antibiotics in Modic Changes (AIM) study ... -
Longitudinal Relationship Between Reduced Modic Change Edema and Disability and Pain in Patients With Chronic Low Back Pain
Espeland, Ansgar; Kristoffersen, Per Martin; Bråten, Lars Christian Haugli; Grøvle, Lars; Grotle, Margreth; Haugen, Anne Julsrud; Rolfsen, Mads Peder; Hellum, Christian; Zwart, John Anker Henrik; Storheim, Kjersti; Assmus, Jörg; Vetti, Nils (Peer reviewed; Journal article, 2023)Study Design. Secondary analyses of a randomized trial [Antibiotics In Modic changes (MCs) study]. Objective. To assess whether or not reduced MC edema over time is related to reduced disability and pain in patients ... -
Low social acceptance among peers increases the risk of persistent musculoskeletal pain in adolescents: Prospective data from the Fit Futures Study
Jahre, Henriette; Grotle, Margreth; Smedbråten, Kaja; Richardsen, Kåre Rønn; Côté, Pierre; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Storheim, Kjersti; Småstuen, Milada Cvancarova; Stensland, Synne; Øiestad, Britt Elin (Peer reviewed; Journal article, 2022)Musculoskeletal pain has a high prevalence in adolescence and causes huge consequences for the individuals and the society. Little knowledge exists on social risk factors for musculoskeletal pain in adolescents. This study ... -
Lumbar spine surgery across 15 years: Trends, complications and reoperations in a longitudinal observational study from Norway
Grotle, Margreth; Småstuen, Milada Cvancarova; Fjeld, Olaf Randall; Grøvle, Lars; Helgeland, Jon; Storheim, Kjersti; Solberg, Tore; Zwart, John-Anker (BMJ Open;Volume 9, Issue 8, Journal article; Journal article; Peer reviewed, 2019-06-25)Background: Studies from different Western countries have reported a rapid increase in spinal surgery rates, an increase that exceeds by far the growing incidence rates of spinal disorders in the general population. There ...