Now showing items 21-26 of 26

    • Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab 

      Jabeen, Shakila; Zucknick, Karola Manuela; Nome, Marianne Eikhom; Dannenfelser, Ruth; Fleischer, Thomas; Kumar, Surendra; Luders, Torben; Gythfeldt, Hedda; Troyanskya, Olga; Kyte, Jon A.; Børresen-Dale, Anne-Lise; Naume, Bjørn; Tekpli, Xavier; Engebråten, Olav; Kristensen, Vessela N. (Taylor & Francis, 2018-01-08)
      A high concentration of circulating vascular endothelial growth factor (VEGF) in cancer patients is associated with an aggressive tumor phenotype. Here, serum levels of 27 cytokines and blood cell counts were assessed in ...
    • Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer 

      Bemanian, Vahid; Noone, John Cristopher; Sauer, Torill; Touma, Joel Joul; Vetvik, Katja K.; Söderberg-Naucler, Cecilia; Lindstrøm, Jonas Christoffer; Bukholm, Ida Rashida Khan; Kristensen, Vessela N.; Geisler, Jürgen (Springer, 2018-08-21)
      Purpose We have compared the mutational profiles of human breast cancer tumor samples belonging to all major subgroups with special emphasis on triple-negative breast cancer (TNBC). Our major goal was to identify specific ...
    • A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America 

      Rossi, Benedito Mauro; Palmero, Edenir Inêz; López-Kostner, Francisco; Sarroca, Carlos; Vaccaro, Carlos Alberto; Spirandelli, Florencia; Ashton-Prolla, Patricia; Rodriguez, Yenni; Galvão, Henrique de Campos Reis; Reis, Rui Manuel; dePaula, André Escremim; Romagnolo, Luis Gustavo Capochin; Alvarez, Karin; Valle, Adriana Della; Neffa, Florencia; Kalfayan, Pablo German; Spirandelli, Enrique; Chialina, Sergio; Angulo, Melva Gutiérrez; Castro-Mujica, Maria del Carmen; de Monte, Julio Sanchez; Quispe, Richard; de Silva, Sabrina Daniela; Rossi, Norma Teresa; Barletta-Carrillo, Claudia; Revollo, Susann; Taborga, Ximena; Morillas, L. Lena; Tubeuf, Hélène; Monteiro-Santos, Erika Maria; Piñero, Tamara Alejandra; Dominguez-Barrera, Constantino; Wernhoff, Patrik; Martins, Alexandra; Hovig, Eivind; Møller, Pål; Valentin, Mev Dominguez (BMC Springer, 2017-09-05)
      Background Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants ...
    • Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations 

      Møller, Elen Kristine; Nord, Silje; Wedge, David C.; Lingjærde, Ole Christian; Silwal-Pandit, Laxmi; Gythfeldt, Hedda; Vollan, Hans Kristian Moen; Fleischer, Thomas; Krohn, Marit; Schlichting, Ellen; Borgen, Elin; Garred, Øystein; Holmen, Marit Muri; Wist, Erik; Naume, Bjørn; Van Loo, Peter; Børresen-Dale, Anne-Lise; Engebråten, Olav; Kristensen, Vessela N. (BMC Springer, 2018-11-29)
      Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its ...
    • Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer 

      Klingen, Tor Audun; Chen, Ying; Aas, Hans; Wik, Elisabeth; Akslen, Lars A (2017-11)
      Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion and show strong expression of CD163 in breast cancer. We here investigated the association between CD163-positive macrophages and vascular ...
    • The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium 

      Bonde, Jesper; Ejegod, Ditte Møller; Cuschieri, Kate; Dillner, Joakim; Heideman, Daniëlle A. M.; Quint, Wim; Ribas, Miguel Angel pavon; Padalko, Elizaveta; Christiansen, Irene Kraus; Xu, Lan; Arbyn, Marc (Elsevier, 2018-09-14)
      Background The VALidation of HPV GENoyping Tests (VALGENT) is an international initiative designed to validate HPV assays with genotyping capability. The VALGENT4 protocol differs from previous VALGENT installments as the ...