AHUS - Diagnostikk og teknologi
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Design of the CAPABLE Prototype: Preliminary Results of Citizen Expectations
(Linköping University Electronic Press, 2019-11)Having access to and opportunity to an overview of all personal health-related information is important to citizen health empowerment. Today, citizens can access subsets of their health information through dedicated, ... -
Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics
(Taylor & Francis, 2018-06-05)Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the potential clinical value of infiltrating lymphocytes at the tumor ... -
Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab
(Taylor & Francis, 2018-01-08)A high concentration of circulating vascular endothelial growth factor (VEGF) in cancer patients is associated with an aggressive tumor phenotype. Here, serum levels of 27 cytokines and blood cell counts were assessed in ... -
No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections
(Wiley, 2017-07-24)Staphylococcus aureus bloodstream infections (SABSI) are associated with high morbidity and mortality. The Toll‐like receptor 2 (TLR2) and Toll‐interacting protein (TOLLIP) are important in recognition and regulation of ... -
The copeptin response after physical activity is not associated with cardiac biomarkers or asymptomatic coronary artery disease: The North Sea Race Endurance Exercise Study (NEEDED) 2013
(Elsevier, 2017-10-26)Background:Copeptin concentrations increase both during acute coronary syndrome and following physicalexercise. The relationship between copeptin increase following physical exercise and coronary artery disease(CAD) is ... -
Initial Phase NT-proBNP, but Not Copeptin and High-Sensitivity Cardiac Troponin-T Yielded Diagnostic and Prognostic Information in Addition to Clinical Assessment of Out-of-Hospital Cardiac Arrest Patients With Documented Ventricular Fibrillation
(Frontiers Media, 2018-06-07)Aim: Sudden cardiac arrest (SCA) secondary to ventricular fibrillation (VF) may be due to different cardiac conditions. We investigated whether copeptin, hs-cTnT and NT-proBNP in addition to clinical assessment may help ... -
Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer
(Springer, 2018-08-21)Purpose We have compared the mutational profiles of human breast cancer tumor samples belonging to all major subgroups with special emphasis on triple-negative breast cancer (TNBC). Our major goal was to identify specific ... -
The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium
(Elsevier, 2018-09-14)Background The VALidation of HPV GENoyping Tests (VALGENT) is an international initiative designed to validate HPV assays with genotyping capability. The VALGENT4 protocol differs from previous VALGENT installments as the ... -
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
(BMC Springer, 2018-11-29)Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its ... -
Betydningen av ulike kanaler i verving av blodgivere
(NITO Bioingeniørfaglig institutt, 2018-02-21)Formål: Studiens mål var å fremskaffe kunnskap om ulike måter blodgivere blir rekruttert til blodbanken. Det ble undersøkt om rekrutteringsmåtene blir påvirket av demografiske variabler og om andelene i rekrutteringsmåter ... -
Interval breast cancer rates and histopathologic tumor characteristics after false-positive findings at mammography in a populationbased screening program
(RSNA Radiological Society, 2017-12-14)Purpose To compare rates and tumor characteristics of interval breast cancers (IBCs) detected after a negative versus false-positive screening among women participating in the Norwegian Breast Cancer Screening ... -
Bioingeniøren som diagnostisk samarbeidspartner i helsevesenet
(NITO Bioingeniørfaglig institutt, 2018-04-27)Bakgrunn. Målet med denne studien var å undersøke om en bioingeniør kan inngå som en diagnostisk samarbeidspartner (DSP) og derved oppleves som en naturlig del av et tverrprofesjonelt team i helsevesenet. Metode. Det ... -
Helseatferd blant blodgivere
(NITO Bioingeniørfaglig institutt, 2018-10-02)Formål: Formålet med denne studien var å kartlegge helseatferd (tobakks- og alkoholbruk og fysisk aktivitet) i et utvalg av blodgivere, og undersøke i hvilken grad resultatene fra studien gjenspeiler helseatferd i den ... -
Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer
(2017-11)Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion and show strong expression of CD163 in breast cancer. We here investigated the association between CD163-positive macrophages and vascular ... -
Norwegian patients and retail chicken meat share cephalosporin-resistant Escherichia coli and IncK/blaCMY-2 resistance plasmids
(Elsevier, 2017-06)Objectives In 2012 and 2014 the Norwegian monitoring programme for antimicrobial resistance in the veterinary and food production sectors (NORM-VET) showed that 124 of a total of 406 samples (31%) of Norwegian retail ... -
Peripheral arthritis in patients with long-term inflammatory bowel disease. Results from 20 years of follow-up in the IBSEN study
(Taylor & Francis, 2018-10-24)Objectives: Peripheral arthritis and related musculoskeletal manifestations, often classified as peripheral spondyloarthritis, are frequently seen in patients with inflammatory bowel disease (IBD). Few long-term studies ... -
Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer
(PLOS, 2017-02-15)Presence of lymph node (LN) metastasis is a strong prognostic factor in breast cancer, whereas the importance of extra-nodal extension and other nodal tumor features have not yet been fully recognized. Here, we examined ... -
Ankylosing Spondylitis and Axial Spondyloarthritis in Patients With Long-term Inflammatory Bowel Disease: Results From 20 Years of Follow-up in the IBSEN Study
(Elsevier, 2017-09-13)Background Patients with inflammatory bowel disease [IBD] often suffer from rheumatic manifestations, including inflammatory back disorders. The prevalence of these disorders late in the course of IBD is poorly investigated. ... -
Genotypic characterization of gentamicin and cephalosporin 1 resistant Escherichia coli 2 isolates from blood cultures in a Norwegian university hospital 2011-2015
(BMC Springer, 2017-11-29)Background: Cephalosporin resistance in clinical E. coli isolates is increasing internationally. The increase has been caused by virulent and often multidrug-resistant clones, especially the extended spectrum beta-lactamase ... -
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
(BMC Springer, 2017-09-05)Background Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants ...