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Anti-inflammatory MicroRNAs and their potential for inflammatory diseases treatment
(Frontiers Media S.A., 2018-06-25)
Inflammation is a complicated biological and pathophysiological cascade of responses to infections and injuries, and inflammatory mechanisms are closely related to many diseases. The magnitude, the complicated network of ...
Paracrine Activity from Adipose-Derived Stem Cells on in Vitro Wound Healing in Human Tympanic Membrane Keratinocytes
(Mary Ann Liebert, 2017)
Stem cell therapies for tympanic membrane repair have shown initial experimental success using mesenchymal stem cells in rat models to promote healing; however, the mechanisms providing this benefit are not known. We ...
A review of oxygen use during chest compressions in Newborns-A meta-analysis of animal data
(Frontiers Media S.A., 2018-12-18)
Background: International consensus statements for resuscitation of newborn infants recommend provision of 100% oxygen once chest compressions are required. However, 100% oxygen exacerbates reperfusion injury and reduces ...
The usage of fasting glucose and glycated hemoglobin for the identification of unknown type 2 diabetes in high risk patients with morbid obesity
(Taylor & Francis, 2017-07-17)
Background: In spite of increased vigilance of undiagnosed type 2 diabetes (DM2), the prevalence of unknown DM2 in subjects with morbid obesity is not known.
Aim: To assess the prevalence of undiagnosed DM2 and compare ...
General population norms for the EQ-5D-3 L in Norway: comparison of postal and web surveys
(BMC Springer, 2018-10-19)
Background
The EQ-5D-3 L instrument is a standardized questionnaire which was developed as a simple, generic measure of health for clinical and economic appraisal. To aid in the interpretation, scores are often compared ...
Genotypic characterization of gentamicin and cephalosporin 1 resistant Escherichia coli 2 isolates from blood cultures in a Norwegian university hospital 2011-2015
(BMC Springer, 2017-11-29)
Background: Cephalosporin resistance in clinical E. coli isolates is increasing internationally. The increase has been caused by virulent and often multidrug-resistant clones, especially the extended spectrum beta-lactamase ...
Early introduction of oral paricalcitol in renal transplant recipients. An open-label randomized study
(Wiley, 2017-04-24)
In stable renal transplant recipients with hyperparathyroidism, previous studies have indicated that vitamin D agonist treatment might have anti-proteinuric effects. Animal studies indicate possible anti-fibrotic and ...
Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: A case series
(BMC Springer, 2018-05-16)
Background
The lack of an antidote against factor Xa inhibitors in case of major bleeding or need for urgent surgery is a concern to clinicians. Guidelines on managing major bleeding in patients under anticoagulation with ...
Two novel connexin32 mutations cause early onset X-linked Charcot-Marie-Tooth disease
(BioMed Central, 2007-07-09)
Background
X-linked Charcot-Marie Tooth (CMT) is caused by mutations in the connexin32 gene that encodes a polypeptide which is arranged in hexameric array and form gap junctions.
Methods
We describe two novel ...
Physical distress is associated with cardiovascular events in a high
(BioMed Central, 2009-03-30)
Background: Self-reported health perceptions such as physical distress and quality of life are
suggested independent predictors of mortality and morbidity in patients with established
cardiovascular disease. This study ...