Blar i Akershus Universitetssykehus HF på emneord "NAD+; metabolism; autophagy; neurodegenerative disorder; mitophagy; aging; stem cell; DNA repair; clinical application"

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    • NAD+ in aging: molecular mechanisms and translational implications 

      Fang, Evandro Fei; Lautrup, Sofie; Hou, Yujun; Demarest, Tyler G; Croteau, Deborah L; Mattson, Mark P; Bohr, Vilhelm A (Trends in Molecular Medicine;23/10, Journal article; Peer reviewed, 2017-10)
      AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of ...