Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
dc.contributor.author | Tashbayev, Behzod | |
dc.contributor.author | Garen, Torhild Oddveig | |
dc.contributor.author | Palm, Øyvind | |
dc.contributor.author | Chen, Xiangjun | |
dc.contributor.author | Herlofson, Bente Brokstad | |
dc.contributor.author | Young Vik, Alix Rosslyn | |
dc.contributor.author | Hove, Lene Hystad | |
dc.contributor.author | Rykke, Morten | |
dc.contributor.author | Singh, Preet Bano | |
dc.contributor.author | Aqrawi, Lara Adnan | |
dc.contributor.author | Utheim, Øygunn Aass | |
dc.contributor.author | Utheim, Tor Paaske | |
dc.contributor.author | Jensen, Janicke Cecilie Liaaen | |
dc.date.accessioned | 2020-05-15T20:25:40Z | |
dc.date.accessioned | 2020-05-18T08:48:10Z | |
dc.date.available | 2020-05-15T20:25:40Z | |
dc.date.available | 2020-05-18T08:48:10Z | |
dc.date.issued | 2020-02-07 | |
dc.identifier.citation | Tashbayev, B., Garen, T.O., Palm, Ø., Chen, X., Herlofson, B.B., Young, A.R.V. & Jensen, J.C.L. (2020). Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study. Scientific Reports, 10(2063). doi:10.1038/s41598-020-59078-0 | en |
dc.identifier.issn | 2045-2322 | |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | https://hdl.handle.net/10642/8611 | |
dc.description.abstract | Understanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral and ocular dryness were performed in age- and sex-matched patients with primary Sjögren’s syndrome (pSS group), non-Sjögren’s syndrome sicca (non-SS group) and healthy controls. General and oral health-related quality of life were investigated with the 36-Item Short Form Health Survey and the 14-Item Oral Health Impact Profle questionnaires, respectively. Subjective symptoms of xerostomia and ocular dryness were recorded using the Summated Xerostomia Inventory and Ocular Surface Disease Index, respectively. Clinical examinations included evaluation of clinical oral dryness scores, candida counts, unstimulated and stimulated saliva secretory rates, tear osmolarity, tear flm break-up time, Schirmer I test and ocular surface staining. Both patient groups had pronounced signs and symptoms of xerostomia and ocular dryness. Even though the non-SS patients had less severe clinical signs than the pSS patients, they demonstrated much poorer general and oral health-related quality of life. In conclusion, non-SS patients require more attention in order to improve their quality of life. | en |
dc.language.iso | en | en |
dc.publisher | Nature Research (part of Springer Nature) | en |
dc.relation.ispartofseries | Scientific Reports;10, Article number: 2063 (2020) | |
dc.rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2020 | en |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Oral health | en |
dc.subject | Life qualities | en |
dc.subject | Patient management | en |
dc.subject | Sjögrens syndrome | en |
dc.title | Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study | en |
dc.type | Journal article | en |
dc.type | Peer reviewed | en |
dc.date.updated | 2020-05-15T20:25:40Z | |
dc.description.version | publishedVersion | en |
dc.identifier.doi | 10.1038/s41598-020-59078-0 | |
dc.identifier.cristin | 1800324 | |
dc.source.journal | Scientific Reports |
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Med mindre annet er angitt, så er denne innførselen lisensiert som This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2020