Trajectories of Depression in Late Life: A 1-Year Follow-Up Study
dc.contributor.author | Borza, Tom | |
dc.contributor.author | Engedal, Knut Arne | |
dc.contributor.author | Bergh, Sverre | |
dc.contributor.author | Saltyte-Benth, Jurate | |
dc.contributor.author | Selbæk, Geir | |
dc.date.accessioned | 2019-08-02T06:38:08Z | |
dc.date.available | 2019-08-02T06:38:08Z | |
dc.date.issued | 2017-04 | |
dc.identifier.citation | Borza, T., Engedal, K., Bergh, S., Benth, J. Š., & Selbæk, G. (2017). Trajectories of Depression in Late Life: A 1-Year Follow-Up Study. Dementia and geriatric cognitive disorders, 43(3-4), 180-192. | en |
dc.identifier.issn | 1420-8008 | |
dc.identifier.uri | https://hdl.handle.net/10642/7383 | |
dc.description.abstract | Aims: To investigate the prognosis of depression in late life (DLL) in terms of the course of depression over 1 year and assess clinical factors related to the prognosis. Methods: We performed an observational, multicenter, longitudinal study of 160 patients aged ≥60 years who were admitted to inward treatment of DLL. The patients were followed with 3 assessments: at inclusion (T0), at discharge from the hospital (T1), and after 1 year (T2). Growth mixture modeling was applied to identify patient classes following distinct trajectories of the Montgomery-Åsberg Depression Rating Scale (MADRS) score. Two regression models were estimated to assess clinical factors for the trajectories and for a clinical assessment of the depression course between T1 and T2. Results: Two trajectory classes were identified: one with higher and one with lower MADRS scores. Not being in remission at T1 and a longer hospital stay were associated with higher odds of being in the trajectory class with more severe depression. Early-onset depression (EOD) was associated with higher odds of being in a group with a poorer clinical course between T1 and T2. Conclusion: EOD and not being in remission at discharge were important negative prognostic factors for DLL. | en |
dc.language.iso | en | en |
dc.publisher | Karger | en |
dc.relation.ispartofseries | Dementia and geriatric cognitive disorders;43(3-4) | |
dc.rights | This is the peer-reviewed but unedited manuscript version of the following article: Borza, T., Engedal, K., Bergh, S., Benth, J. Š., & Selbæk, G. (2017). Trajectories of Depression in Late Life: A 1-Year Follow-Up Study. Dementia and geriatric cognitive disorders, 43(3-4), 180-192. (DOI: 10.1159/000458148). The final, published version is available at https://www.karger.com/?doi=10.1159/000458148 | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.subject | Artikkel | en |
dc.subject | VDP::Medisinske Fag: 700 | en |
dc.title | Trajectories of Depression in Late Life: A 1-Year Follow-Up Study | en |
dc.type | Journal article | en |
dc.type | Peer reviewed | en |
dc.description.version | acceptedVersion | en |
dc.identifier.doi | https://doi.org/10.1159/000458148 | |
dc.identifier.cristin | 1456285 |
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Med mindre annet er angitt, så er denne innførselen lisensiert som This is the peer-reviewed but unedited manuscript version of the following article: Borza, T., Engedal, K., Bergh, S., Benth, J. Š., & Selbæk, G. (2017). Trajectories of Depression in Late Life: A 1-Year Follow-Up Study. Dementia and geriatric cognitive disorders, 43(3-4), 180-192. (DOI: 10.1159/000458148). The final, published version is available at https://www.karger.com/?doi=10.1159/000458148