• Paracrine Activity from Adipose-Derived Stem Cells on in Vitro Wound Healing in Human Tympanic Membrane Keratinocytes 

      Ong, Huan Ting; Redmond, Sharon L.; Marano, Robert J.; Atlas, Marcus D.; Unge, Magnus Von; Aabel, Peder; Dilley, Rodney J. (Stem Cells and Development ISSN 1547-3287 e-ISSN 1557-8534 NVI-nivå 1;26(6), Journal article; Peer reviewed, 2017)
      Stem cell therapies for tympanic membrane repair have shown initial experimental success using mesenchymal stem cells in rat models to promote healing; however, the mechanisms providing this benefit are not known. We ...
    • Rat model of chronic tympanic membrane perforation: A longitudinal histological evaluation of underlying mechanisms 

      Wang, Allen Y; Liew, Lawrence J; Shen, Yi; Wang, Jeffrey T; Unge, Magnus Von; Atlas, Marcus D; Dilley, Rodney J (International Journal of Pediatric Otorhinolaryngology;93, Journal article; Peer reviewed, 2017-02)
      Objective To evaluate histologically the progressive development and underlying mechanisms of chronic tympanic membrane perforation (TMP) in a rat model using a two-weeks ventilation tube (VT) treatment combined with ...
    • Tailored treatment of colorectal cancer: Surgical, molecular, and genetic considerations 

      Augestad, Knut Magne; Merok, Marianne Aarstad; Ignjatovic, Dejan (Clinical Medicine Insights: Oncology;11, Journal article; Peer reviewed, 2017-02-16)
      Colorectal cancer (CRC) is a complex cancer disease, and approximately 40% of the surgically cured patients will experience cancer recurrence within 5 years. During recent years, research has shown that CRC treatment should ...
    • Factors associated with life-sustaining treatment restriction in a general intensive care unit 

      Skjaker, Stein Arve; Hoel, Henrik; Dahl, Vegard; Stavem, Knut (PloS one;12(7), Journal article; Peer reviewed, 2017-07-18)
      Abstract Purpose Few previous studies have investigated associations between clinical variables available after 24 hours in the intensive care unit (ICU), including the Charlson Comorbidity Index (CCI), and decisions to ...
    • Improved Survival after Implementation of Multidisciplinary Team Meetings, Perioperative Chemotherapy, Extended Lymphnode Dissection and Laparoscopic Surgery in the Treatment of Advances Gastric Cancer 

      Gaupset, Robin; Eftang, Lars Lohne; Langbach, Odd; Fridrich, Katrin; Borthne, Arne Sigmund; Geitung, Jonn Terje; Suntharalingam, Sutharsan; Ignjatovic, Dejan; Røkke, Ola (Journal of Cancer Therapy;9(2), Journal article; Peer reviewed, 2018-02)
      Aims: The treatment of gastric cancer has changed in the western countries during the last decade. This includes multidisciplinary team (MDT) meetings, perioperative chemotherapy, extended lymph node dissection, and ...
    • Safe surgery checklist, patient safety, teamwork and responsibility - coequal demands? A Focus Group study 

      Willassen, Elin Thove; Jacobsen, Inger Lise Smith; Tveiten, Sidsel (Global qualitative nursing research;5, Journal article; Peer reviewed, 2018-03-28)
      The use of World Health Organization’s (WHO’s) Safe Surgery checklist is an established practice worldwide and contributes toward ensuring patient safety and collaborative teamwork. The aim of this study was to elucidate ...
    • Balloon eustachian tuboplasty: Systematic review of long-term outcomes and proposed indications 

      Luukkainen, Veera; Kivekäs, Ilkka; Silvola, Juha Tapio; Jero, Jussi; Sinkkonen, Saku T. (The journal of international advanced otology;14(1), Journal article; Peer reviewed, 2018-04)
      Balloon Eustachian tuboplasty (BET) aims to improve the function of the Eustachian tube (ET). The objective of this study was to review the longterm outcome of BET and present the process and results of outlining indications ...
    • Respiratory pump maintains cardiac stroke volume during hypovolemia in young, healthy volunteers 

      Skytioti, Maria; Søvik, Signe; Elstad, Maja (Journal of Applied Physiology;124(5), Journal article; Peer reviewed, 2018-05-24)
      Abstract Spontaneous breathing has beneficial effects on the circulation, since negative intrathoracic pressure enhances venous return and increases cardiac stroke volume. We quantified the contribution of the respiratory ...
    • Introducing anatomically correct CT-guided laparoscopic right colectomy with D3 anterior posterior extended mesenterectomy: Initial experience and technical pitfalls 

      Gaupset, Robin; Næsgaard, Jens Marius; Kazaryan, Airazat; Stimec, Bojan V.; Edwin, Bjørn; Ignjatovic, Dejan (Journal of Laparoendoscopic & Advanced Surgical Techniques;28(10), Journal article; Peer reviewed, 2018-10-10)
      Background: Laparoscopic D3 anterior posterior extended mesenterectomy (D3APEM) in right colectomy has received increased attention. The aim of this study is to prove feasibility, systemize technical accomplishment, and ...
    • Pantoprazole in patients at risk for gastrointestinal bleeding in the ICU 

      Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt; Schefold, Jörg Christian; Keus, Frederik; Guttormsen, Anne Berit; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Rasmussen, Bodil S.; Siegemund, Martin; Bundegaard, Helle; Elkmann, Thomas; Jensen, Jacob V.; Nielsen, Rune D.; Liboriussen, Lisbeth; Bestle, Morten Heiberg; Elkjær, Jeanie M.; Palmqvist, Dorte F.; Bäcklund, Minna; Laake, Jon Henrik; Bådstøløkken, Per Martin; Grönlund, Juha; Breum, Olena; Walli, Akil; Winding, Robert; Iversen, Susanne; Jarnvig, Inger-Lise; White, Jonathan O.; Brand, Björn; Madsen, Martin Bruun; Quist, Lars; Thornberg, Klaus J.; Møller, Anders; Wiis, Jørgen; Granholm, Anders; Anthon, Carl Thomas; Meyhoff, Tine Sylvest; Hjortrup, Peter B.; Aagard, Søren R.; Andreassen, Jo B.; Sørensen, Christina Ankjær; Haure, Pernille; Hauge, Jacob; Hollinger, Alexa; Scheuzger, Jonas; Tuchscherer, Daniel; Vuilliomenet, Thierry; Takala, Jukka; Jacob, Stephan M.; Vang, Marianne L.; Pælestik, Kim B.; Andersen, Karen L. D.; van der Horst, Ivan C. C.; Dieperink, Willem; Fjølner, Jesper; Kjer, Cilia Klara Winther; Sølling, Christoffer G.; Karttunen, Johanna; Morgan, Matt P. G.; Sjøbø, Brit Ågot; Engstrøm, Janus; Agerholm-Larsen, Birgit; Møller, Morten H. (New England Journal of Medicine;379(23), Journal article; Peer reviewed, 2018-12-06)
      BACKGROUND Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. METHODS In this European, multicenter, parallel-group, ...
    • Acute uncomplicated diverticulitis managed without antibiotics – difficult to introduce a new treatment protocol but few complications 

      Azhar, Najia; Kulstad, Hanna; Pålsson, Birger; Schultz, Johannes Kurt; Lydrup, Marie-Louise; Buchwald, Pamela (Scandinavian journal of gastroenterology;54(1), Journal article; Peer reviewed, 2019-01-16)
      Objective: Routine antibiotic treatment of acute uncomplicated diverticulitis (AUD) has been shown ineffective. In this study, the adherence to a new treatment protocol for uncomplicated diverticulitis was evaluated and ...